FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4381330789> ?p ?o ?g. }

• W4381330789 abstract "Abstract Background SARS-CoV-2 has been well studied in resource-rich areas but many questions remain about effects of infection in African populations, particularly in vulnerable groups such as pregnant women. Methods We describe SARS-CoV-2 immunoglobulin (Ig) G and IgM antibody responses and clinical outcomes in mother-infant dyads enrolled in malaria chemoprevention trials in Uganda. Results From December 2020 to February 2022, among 400 unvaccinated pregnant women, serologic assessments revealed that 128 (32%) were seronegative for anti-SARS-CoV-2 IgG and IgM at enrollment and delivery, 80 (20%) were infected either prior to or early in pregnancy, and 192 (48%) were infected or re-infected with SARS-CoV-2 during pregnancy. We observed preferential binding of plasma IgG to Wuhan-Hu-1-like antigens in individuals seroconverting up to early 2021, and to Delta variant antigens in a subset of individuals in mid-2021. Breadth of IgG binding to all variants improved over time. No participants experienced severe respiratory illness during the study. SARS-CoV-2 infection in early pregnancy was associated with lower median length-for-age Z-score at age 3 months compared with no infection or late pregnancy infection (- 1.54 versus −0.37 and −0.51, p=0.009). Conclusion Pregnant Ugandan women experienced high levels of SARS-CoV-2 infection without severe respiratory illness. Variant-specific serology testing demonstrated evidence of antibody affinity maturation at the population level. Early gestational SARS-CoV-2 infection was associated with shorter stature in early infancy. Funding This work was supported by: Stanford MCHRI/Stephen Bechtel Endowed Fellowship in Pediatric Translational Medicine (KJ), Swiss National Science Foundation PRIMA grant PR00P3_208580 (KR), the Bill and Melinda Gates Foundation, and NIAID (T32-AI052073, U01- AI141308, U01-AI155325)." @default.
• W4381330789 created "2023-06-21" @default.
• W4381330789 creator A5014396784 @default.
• W4381330789 creator A5019121073 @default.
• W4381330789 creator A5020750841 @default.
• W4381330789 creator A5020931494 @default.
• W4381330789 creator A5026667682 @default.
• W4381330789 creator A5029682053 @default.
• W4381330789 creator A5031846220 @default.
• W4381330789 creator A5032334189 @default.
• W4381330789 creator A5033897984 @default.
• W4381330789 creator A5036212755 @default.
• W4381330789 creator A5037723209 @default.
• W4381330789 creator A5040257843 @default.
• W4381330789 creator A5046059142 @default.
• W4381330789 creator A5048004017 @default.
• W4381330789 creator A5054207126 @default.
• W4381330789 creator A5059133928 @default.
• W4381330789 creator A5064302758 @default.
• W4381330789 creator A5064442163 @default.
• W4381330789 creator A5067026117 @default.
• W4381330789 creator A5073474746 @default.
• W4381330789 creator A5077631479 @default.
• W4381330789 creator A5078306983 @default.
• W4381330789 creator A5083823135 @default.
• W4381330789 creator A5084940314 @default.
• W4381330789 creator A5092212738 @default.
• W4381330789 date "2023-06-20" @default.
• W4381330789 modified "2023-10-18" @default.
• W4381330789 title "High rates of SARS-CoV-2 infection in pregnant Ugandan women and association with stunting in infancy" @default.
• W4381330789 cites W1951724000 @default.
• W4381330789 cites W1963525812 @default.
• W4381330789 cites W2310319955 @default.
• W4381330789 cites W2979575798 @default.
• W4381330789 cites W3024263301 @default.
• W4381330789 cites W3037173725 @default.
• W4381330789 cites W3111459703 @default.
• W4381330789 cites W3127013662 @default.
• W4381330789 cites W3129275326 @default.
• W4381330789 cites W3138907726 @default.
• W4381330789 cites W3140253808 @default.
• W4381330789 cites W3160530878 @default.
• W4381330789 cites W3163896268 @default.
• W4381330789 cites W3178967291 @default.
• W4381330789 cites W3201155118 @default.
• W4381330789 cites W4200199783 @default.
• W4381330789 cites W4205332694 @default.
• W4381330789 cites W4206605585 @default.
• W4381330789 cites W4207077800 @default.
• W4381330789 cites W4210943449 @default.
• W4381330789 cites W4220652343 @default.
• W4381330789 cites W4220967789 @default.
• W4381330789 cites W4224272725 @default.
• W4381330789 cites W4224539925 @default.
• W4381330789 cites W4225718889 @default.
• W4381330789 cites W4281641281 @default.
• W4381330789 cites W4292774342 @default.
• W4381330789 cites W4296703853 @default.
• W4381330789 cites W4311716645 @default.
• W4381330789 cites W4316928669 @default.
• W4381330789 cites W4320856906 @default.
• W4381330789 cites W4322741960 @default.
• W4381330789 cites W4361281151 @default.
• W4381330789 doi "https://doi.org/10.1101/2023.06.16.23291450" @default.
• W4381330789 hasPublicationYear "2023" @default.
• W4381330789 type Work @default.
• W4381330789 citedByCount "0" @default.
• W4381330789 crossrefType "posted-content" @default.
• W4381330789 hasAuthorship W4381330789A5014396784 @default.
• W4381330789 hasAuthorship W4381330789A5019121073 @default.
• W4381330789 hasAuthorship W4381330789A5020750841 @default.
• W4381330789 hasAuthorship W4381330789A5020931494 @default.
• W4381330789 hasAuthorship W4381330789A5026667682 @default.
• W4381330789 hasAuthorship W4381330789A5029682053 @default.
• W4381330789 hasAuthorship W4381330789A5031846220 @default.
• W4381330789 hasAuthorship W4381330789A5032334189 @default.
• W4381330789 hasAuthorship W4381330789A5033897984 @default.
• W4381330789 hasAuthorship W4381330789A5036212755 @default.
• W4381330789 hasAuthorship W4381330789A5037723209 @default.
• W4381330789 hasAuthorship W4381330789A5040257843 @default.
• W4381330789 hasAuthorship W4381330789A5046059142 @default.
• W4381330789 hasAuthorship W4381330789A5048004017 @default.
• W4381330789 hasAuthorship W4381330789A5054207126 @default.
• W4381330789 hasAuthorship W4381330789A5059133928 @default.
• W4381330789 hasAuthorship W4381330789A5064302758 @default.
• W4381330789 hasAuthorship W4381330789A5064442163 @default.
• W4381330789 hasAuthorship W4381330789A5067026117 @default.
• W4381330789 hasAuthorship W4381330789A5073474746 @default.
• W4381330789 hasAuthorship W4381330789A5077631479 @default.
• W4381330789 hasAuthorship W4381330789A5078306983 @default.
• W4381330789 hasAuthorship W4381330789A5083823135 @default.
• W4381330789 hasAuthorship W4381330789A5084940314 @default.
• W4381330789 hasAuthorship W4381330789A5092212738 @default.
• W4381330789 hasBestOaLocation W43813307891 @default.
• W4381330789 hasConcept C126322002 @default.
• W4381330789 hasConcept C147483822 @default.
• W4381330789 hasConcept C159654299 @default.
• W4381330789 hasConcept C187212893 @default.
• W4381330789 hasConcept C203014093 @default.
• W4381330789 hasConcept C2778376644 @default.

• next