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- W4381416559 abstract "For this study, we investigated the minimum number of short tandem repeat (STR) and single nucleotide polymorphism (SNP) loci sufficient for personal identification in the Japanese population. A guidance for the data volume that should be treated as personal information was presented here. The uniqueness of individual genotypes was evaluated according to the Scientific Working Group on DNA Analysis Methods interpretation guideline, using the probability that another individual would have the same genotype by chance. In the Japanese population, the threshold of random match probability sufficient for personal identification was 8.15×10－11. In STR, it was considered that when 9 or more of the 21 autosomal STR loci of the GlobalFiler system were combined, they should correspond to personal information. For SNP, a total of 112 loci should be required for identification when cumulating the number of loci at the minor allele frequency interval of 0.01. However, based on the median of allele distribution, a total of 47 loci were necessary to reach below the threshold. Furthermore, we simulated the number of the required loci when the size of the population was variable. Since genome data is already widely used in society, we need to recognize that strict management of genome data are essential from the viewpoint of protecting personal information." @default.
- W4381416559 created "2023-06-21" @default.
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- W4381416559 date "2023-01-01" @default.
- W4381416559 modified "2023-09-29" @default.
- W4381416559 title "日本人集団において個人を識別するのに必要なSTRとSNPの最小座位数" @default.
- W4381416559 doi "https://doi.org/10.3408/jafst.856" @default.
- W4381416559 hasPublicationYear "2023" @default.
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