Matches in SemOpenAlex for { <https://semopenalex.org/work/W4381462630> ?p ?o ?g. }
Showing items 1 to 91 of
91
with 100 items per page.
- W4381462630 abstract "Objective The purpose of this study was to estimate the safety and efficacy of spray cryotherapy (SCT) in patients with chronic obstructive pulmonary disease (COPD). Methods We recruited patients aged 40–80 years with a confirmed diagnosis of COPD without serious complications (defined as two consecutive years of chronic cough and cough for at least 3 months with lung function forced expiratory volume in 1 s [FEV1]/forced vital capacity [FVC] < 70% after inhaled bronchodilators and Global Initiative for Chronic Obstructive Lung Disease [GOLD] grade II–IV). The safety of this study was assessed by incidence of adverse events, and the efficacy was evaluated by St. George's Respiratory Questionnaire (SGRQ), COPD assessment test (CAT), Leicester Cough Questionnaire (LCQ) and changes in exercise capacity, histomorphology and lung function. Results Eight patients eventually received three complete sessions of SCT, each lasting 41.10 ± 19.72 min. No adverse complications were recorded within 3 months after SCT. Clinically meaningful improvements in SGRQ, CAT, LCQ and exercise capacity were observed at 3 months after SCT: −15.75 ± 6.76 (95% confidence interval [CI] 10.10−21.40; p < .001), −6.88 ± 3.91 (95% CI 3.61−10.14; p = .002), −18.13 ± 13.81 (95% CI 6.58−29.67; p = .008) and 72.75 ± 33.11 (95% CI −100.43 to −45.07; p < .001), respectively. The density of airway epithelial goblet cells per unit area was significantly reduced (p < .05), and lung function parameters such as ∆FVC, ∆FEV1 and ∆ peak expiratory flow (∆PEF) were improved (p = .007, .021 and .012). Conclusions SCT is a safe and effective strategy to provide a better quality of life for COPD patients." @default.
- W4381462630 created "2023-06-21" @default.
- W4381462630 creator A5000828146 @default.
- W4381462630 creator A5055815135 @default.
- W4381462630 creator A5058956678 @default.
- W4381462630 creator A5062978915 @default.
- W4381462630 creator A5067669293 @default.
- W4381462630 creator A5077845197 @default.
- W4381462630 date "2023-05-09" @default.
- W4381462630 modified "2023-09-26" @default.
- W4381462630 title "A prospective study of spray cryotherapy in patients with COPD" @default.
- W4381462630 cites W2004228348 @default.
- W4381462630 cites W2053308987 @default.
- W4381462630 cites W2054931962 @default.
- W4381462630 cites W2062504205 @default.
- W4381462630 cites W2113558571 @default.
- W4381462630 cites W2118964405 @default.
- W4381462630 cites W2332115261 @default.
- W4381462630 cites W2408848005 @default.
- W4381462630 cites W2518119976 @default.
- W4381462630 cites W2587864816 @default.
- W4381462630 cites W2595062268 @default.
- W4381462630 cites W2599637497 @default.
- W4381462630 cites W2921892224 @default.
- W4381462630 cites W2997825069 @default.
- W4381462630 cites W3126201446 @default.
- W4381462630 cites W4224274811 @default.
- W4381462630 doi "https://doi.org/10.1002/ctd2.192" @default.
- W4381462630 hasPublicationYear "2023" @default.
- W4381462630 type Work @default.
- W4381462630 citedByCount "0" @default.
- W4381462630 crossrefType "journal-article" @default.
- W4381462630 hasAuthorship W4381462630A5000828146 @default.
- W4381462630 hasAuthorship W4381462630A5055815135 @default.
- W4381462630 hasAuthorship W4381462630A5058956678 @default.
- W4381462630 hasAuthorship W4381462630A5062978915 @default.
- W4381462630 hasAuthorship W4381462630A5067669293 @default.
- W4381462630 hasAuthorship W4381462630A5077845197 @default.
- W4381462630 hasBestOaLocation W43814626301 @default.
- W4381462630 hasConcept C120665830 @default.
- W4381462630 hasConcept C121332964 @default.
- W4381462630 hasConcept C126322002 @default.
- W4381462630 hasConcept C141071460 @default.
- W4381462630 hasConcept C165637977 @default.
- W4381462630 hasConcept C197934379 @default.
- W4381462630 hasConcept C2776042228 @default.
- W4381462630 hasConcept C2776780178 @default.
- W4381462630 hasConcept C2777707825 @default.
- W4381462630 hasConcept C2777714996 @default.
- W4381462630 hasConcept C2780149145 @default.
- W4381462630 hasConcept C3018587741 @default.
- W4381462630 hasConcept C44249647 @default.
- W4381462630 hasConcept C55520419 @default.
- W4381462630 hasConcept C61511704 @default.
- W4381462630 hasConcept C71924100 @default.
- W4381462630 hasConcept C75603125 @default.
- W4381462630 hasConceptScore W4381462630C120665830 @default.
- W4381462630 hasConceptScore W4381462630C121332964 @default.
- W4381462630 hasConceptScore W4381462630C126322002 @default.
- W4381462630 hasConceptScore W4381462630C141071460 @default.
- W4381462630 hasConceptScore W4381462630C165637977 @default.
- W4381462630 hasConceptScore W4381462630C197934379 @default.
- W4381462630 hasConceptScore W4381462630C2776042228 @default.
- W4381462630 hasConceptScore W4381462630C2776780178 @default.
- W4381462630 hasConceptScore W4381462630C2777707825 @default.
- W4381462630 hasConceptScore W4381462630C2777714996 @default.
- W4381462630 hasConceptScore W4381462630C2780149145 @default.
- W4381462630 hasConceptScore W4381462630C3018587741 @default.
- W4381462630 hasConceptScore W4381462630C44249647 @default.
- W4381462630 hasConceptScore W4381462630C55520419 @default.
- W4381462630 hasConceptScore W4381462630C61511704 @default.
- W4381462630 hasConceptScore W4381462630C71924100 @default.
- W4381462630 hasConceptScore W4381462630C75603125 @default.
- W4381462630 hasIssue "3" @default.
- W4381462630 hasLocation W43814626301 @default.
- W4381462630 hasOpenAccess W4381462630 @default.
- W4381462630 hasPrimaryLocation W43814626301 @default.
- W4381462630 hasRelatedWork W2354650335 @default.
- W4381462630 hasRelatedWork W2368903326 @default.
- W4381462630 hasRelatedWork W2375752930 @default.
- W4381462630 hasRelatedWork W2389259898 @default.
- W4381462630 hasRelatedWork W2926098451 @default.
- W4381462630 hasRelatedWork W3030903414 @default.
- W4381462630 hasRelatedWork W3106854829 @default.
- W4381462630 hasRelatedWork W3163049859 @default.
- W4381462630 hasRelatedWork W4210684207 @default.
- W4381462630 hasRelatedWork W4365483000 @default.
- W4381462630 hasVolume "3" @default.
- W4381462630 isParatext "false" @default.
- W4381462630 isRetracted "false" @default.
- W4381462630 workType "article" @default.