Matches in SemOpenAlex for { <https://semopenalex.org/work/W4381469319> ?p ?o ?g. }
- W4381469319 endingPage "300" @default.
- W4381469319 startingPage "291" @default.
- W4381469319 abstract "The aim of this study was to explore associations of aromatic amino acids (AAA) in early pregnancy with gestational diabetes mellitus (GDM), and whether high AAA and gut microbiota-related metabolites had interactive effects on GDM risk.We conducted a 1:1 case-control study (n = 486) nested in a prospective cohort of pregnant women from 2010 to 2012. According to the International Association of Diabetes and Pregnancy Study Group's criteria, 243 women were diagnosed with GDM. Binary conditional logistic regression was performed to examine associations of AAA with GDM risk. Interactions between AAA and gut microbiota-related metabolites for GDM were examined using additive interaction measures.High phenylalanine and tryptophan were associated with increased GDM risk (OR: 1.72, 95% CI: 1.07-2.78 and 1.66, 1.02-2.71). The presence of high trimethylamine (TMA) markedly increased the OR of high phenylalanine alone up to 7.95 (2.79-22.71), while the presence of low glycoursodeoxycholic acid (GUDCA) markedly increased the OR of high tryptophan alone up to 22.88 (5.28-99.26), both with significant additive interactions. Furthermore, high lysophosphatidylcholines (LPC18:0) mediated both interactive effects.High phenylalanine may have an additive interaction with high TMA, while high tryptophan may have an additive interaction with low GUDCA toward increased risk of GDM, both being mediated via LPC18:0." @default.
- W4381469319 created "2023-06-22" @default.
- W4381469319 creator A5003496336 @default.
- W4381469319 creator A5014606762 @default.
- W4381469319 creator A5027815446 @default.
- W4381469319 creator A5029170981 @default.
- W4381469319 creator A5040507070 @default.
- W4381469319 creator A5056670433 @default.
- W4381469319 creator A5057110014 @default.
- W4381469319 creator A5058771749 @default.
- W4381469319 creator A5061043888 @default.
- W4381469319 creator A5067492238 @default.
- W4381469319 creator A5087313479 @default.
- W4381469319 creator A5090366405 @default.
- W4381469319 date "2023-01-01" @default.
- W4381469319 modified "2023-10-15" @default.
- W4381469319 title "Aromatic Amino Acids and Their Interactions with Gut Microbiota-Related Metabolites for Risk of Gestational Diabetes: A Prospective Nested Case-Control Study in a Chinese Cohort" @default.
- W4381469319 cites W1583556399 @default.
- W4381469319 cites W1828812464 @default.
- W4381469319 cites W1971262359 @default.
- W4381469319 cites W1971383683 @default.
- W4381469319 cites W1980263659 @default.
- W4381469319 cites W1981023596 @default.
- W4381469319 cites W1995187187 @default.
- W4381469319 cites W2007598765 @default.
- W4381469319 cites W2017771330 @default.
- W4381469319 cites W2029313614 @default.
- W4381469319 cites W2037482553 @default.
- W4381469319 cites W2058117698 @default.
- W4381469319 cites W2060552707 @default.
- W4381469319 cites W2080228970 @default.
- W4381469319 cites W2081271380 @default.
- W4381469319 cites W2127459955 @default.
- W4381469319 cites W2141414207 @default.
- W4381469319 cites W2145665725 @default.
- W4381469319 cites W2147259528 @default.
- W4381469319 cites W2152028368 @default.
- W4381469319 cites W2332974872 @default.
- W4381469319 cites W2338627428 @default.
- W4381469319 cites W2404504991 @default.
- W4381469319 cites W2483234986 @default.
- W4381469319 cites W2556034984 @default.
- W4381469319 cites W2604949071 @default.
- W4381469319 cites W2616235706 @default.
- W4381469319 cites W2779487628 @default.
- W4381469319 cites W2797029476 @default.
- W4381469319 cites W2806227292 @default.
- W4381469319 cites W2885109150 @default.
- W4381469319 cites W2921935358 @default.
- W4381469319 cites W2966691578 @default.
- W4381469319 cites W2969960763 @default.
- W4381469319 cites W2997861401 @default.
- W4381469319 cites W3008842756 @default.
- W4381469319 cites W3015330164 @default.
- W4381469319 cites W3016572394 @default.
- W4381469319 cites W3047668443 @default.
- W4381469319 cites W3107083588 @default.
- W4381469319 cites W3121907268 @default.
- W4381469319 cites W3124560030 @default.
- W4381469319 cites W3194771178 @default.
- W4381469319 cites W4200161781 @default.
- W4381469319 cites W4220719481 @default.
- W4381469319 doi "https://doi.org/10.1159/000531481" @default.
- W4381469319 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37339616" @default.
- W4381469319 hasPublicationYear "2023" @default.
- W4381469319 type Work @default.
- W4381469319 citedByCount "0" @default.
- W4381469319 crossrefType "journal-article" @default.
- W4381469319 hasAuthorship W4381469319A5003496336 @default.
- W4381469319 hasAuthorship W4381469319A5014606762 @default.
- W4381469319 hasAuthorship W4381469319A5027815446 @default.
- W4381469319 hasAuthorship W4381469319A5029170981 @default.
- W4381469319 hasAuthorship W4381469319A5040507070 @default.
- W4381469319 hasAuthorship W4381469319A5056670433 @default.
- W4381469319 hasAuthorship W4381469319A5057110014 @default.
- W4381469319 hasAuthorship W4381469319A5058771749 @default.
- W4381469319 hasAuthorship W4381469319A5061043888 @default.
- W4381469319 hasAuthorship W4381469319A5067492238 @default.
- W4381469319 hasAuthorship W4381469319A5087313479 @default.
- W4381469319 hasAuthorship W4381469319A5090366405 @default.
- W4381469319 hasConcept C126322002 @default.
- W4381469319 hasConcept C134018914 @default.
- W4381469319 hasConcept C151956035 @default.
- W4381469319 hasConcept C165617652 @default.
- W4381469319 hasConcept C188816634 @default.
- W4381469319 hasConcept C201903717 @default.
- W4381469319 hasConcept C203014093 @default.
- W4381469319 hasConcept C2776706248 @default.
- W4381469319 hasConcept C2777431362 @default.
- W4381469319 hasConcept C2777992278 @default.
- W4381469319 hasConcept C2779234561 @default.
- W4381469319 hasConcept C2779434492 @default.
- W4381469319 hasConcept C42407357 @default.
- W4381469319 hasConcept C46973012 @default.
- W4381469319 hasConcept C515207424 @default.
- W4381469319 hasConcept C539455810 @default.
- W4381469319 hasConcept C54355233 @default.
- W4381469319 hasConcept C55493867 @default.