Matches in SemOpenAlex for { <https://semopenalex.org/work/W4381469718> ?p ?o ?g. }
Showing items 1 to 83 of
83
with 100 items per page.
- W4381469718 abstract "Patients with systemic lupus erythematosus (SLE) occasionally develop thrombotic thrombocytopenic purpura (TTP), which can be fatal. Here, we report a case of TTP developing 3 years after SLE remitted with rituximab (RTX) therapy. A 50-year-old woman was treated with RTX for marked immune thrombocytopenic purpura and autoimmune haemolytic anaemia due to SLE relapse. After induction of remission, she was treated with prednisolone alone without maintenance therapy with RTX. Approximately 3 years later, she was readmitted with marked thrombocytopenia and severe renal dysfunction. On admission, she was diagnosed with TTP for the first time based on severe reduction in a disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13 (ADAMTS13) activity and detection of ADAMTS13 inhibitors. CD19+ B cells in the patient's serum increased to 34%, suggesting that B cells had reactivated once the effect of RTX had subsided. The patient was successfully treated with plasmapheresis, glucocorticoid pulse therapy, and RTX. There are no previous reports of newly diagnosed TTP with ADAMTS13 inhibitor production after having achieved remission of SLE with RTX. Therefore, our report also discusses the potential mechanisms of production of new autoantibodies after B-cell depletion therapy." @default.
- W4381469718 created "2023-06-22" @default.
- W4381469718 creator A5006259653 @default.
- W4381469718 creator A5034521388 @default.
- W4381469718 creator A5038882714 @default.
- W4381469718 creator A5042811273 @default.
- W4381469718 creator A5043985483 @default.
- W4381469718 creator A5056797112 @default.
- W4381469718 creator A5067916577 @default.
- W4381469718 creator A5070737875 @default.
- W4381469718 creator A5086898372 @default.
- W4381469718 creator A5092222016 @default.
- W4381469718 date "2023-06-10" @default.
- W4381469718 modified "2023-09-25" @default.
- W4381469718 title "Thrombotic thrombocytopenic purpura that developed 3 years after systemic lupus erythematosus had remitted with rituximab therapy." @default.
- W4381469718 doi "https://doi.org/10.1093/mrcr/rxad032" @default.
- W4381469718 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37341710" @default.
- W4381469718 hasPublicationYear "2023" @default.
- W4381469718 type Work @default.
- W4381469718 citedByCount "0" @default.
- W4381469718 crossrefType "journal-article" @default.
- W4381469718 hasAuthorship W4381469718A5006259653 @default.
- W4381469718 hasAuthorship W4381469718A5034521388 @default.
- W4381469718 hasAuthorship W4381469718A5038882714 @default.
- W4381469718 hasAuthorship W4381469718A5042811273 @default.
- W4381469718 hasAuthorship W4381469718A5043985483 @default.
- W4381469718 hasAuthorship W4381469718A5056797112 @default.
- W4381469718 hasAuthorship W4381469718A5067916577 @default.
- W4381469718 hasAuthorship W4381469718A5070737875 @default.
- W4381469718 hasAuthorship W4381469718A5086898372 @default.
- W4381469718 hasAuthorship W4381469718A5092222016 @default.
- W4381469718 hasConcept C126322002 @default.
- W4381469718 hasConcept C159654299 @default.
- W4381469718 hasConcept C163764329 @default.
- W4381469718 hasConcept C170286685 @default.
- W4381469718 hasConcept C203014093 @default.
- W4381469718 hasConcept C2776912625 @default.
- W4381469718 hasConcept C2778453870 @default.
- W4381469718 hasConcept C2778585876 @default.
- W4381469718 hasConcept C2778842783 @default.
- W4381469718 hasConcept C2779134260 @default.
- W4381469718 hasConcept C2779771385 @default.
- W4381469718 hasConcept C2780653079 @default.
- W4381469718 hasConcept C2780921031 @default.
- W4381469718 hasConcept C2781205201 @default.
- W4381469718 hasConcept C71924100 @default.
- W4381469718 hasConcept C8891405 @default.
- W4381469718 hasConcept C89560881 @default.
- W4381469718 hasConcept C90924648 @default.
- W4381469718 hasConceptScore W4381469718C126322002 @default.
- W4381469718 hasConceptScore W4381469718C159654299 @default.
- W4381469718 hasConceptScore W4381469718C163764329 @default.
- W4381469718 hasConceptScore W4381469718C170286685 @default.
- W4381469718 hasConceptScore W4381469718C203014093 @default.
- W4381469718 hasConceptScore W4381469718C2776912625 @default.
- W4381469718 hasConceptScore W4381469718C2778453870 @default.
- W4381469718 hasConceptScore W4381469718C2778585876 @default.
- W4381469718 hasConceptScore W4381469718C2778842783 @default.
- W4381469718 hasConceptScore W4381469718C2779134260 @default.
- W4381469718 hasConceptScore W4381469718C2779771385 @default.
- W4381469718 hasConceptScore W4381469718C2780653079 @default.
- W4381469718 hasConceptScore W4381469718C2780921031 @default.
- W4381469718 hasConceptScore W4381469718C2781205201 @default.
- W4381469718 hasConceptScore W4381469718C71924100 @default.
- W4381469718 hasConceptScore W4381469718C8891405 @default.
- W4381469718 hasConceptScore W4381469718C89560881 @default.
- W4381469718 hasConceptScore W4381469718C90924648 @default.
- W4381469718 hasLocation W43814697181 @default.
- W4381469718 hasOpenAccess W4381469718 @default.
- W4381469718 hasPrimaryLocation W43814697181 @default.
- W4381469718 hasRelatedWork W1740651174 @default.
- W4381469718 hasRelatedWork W2017142468 @default.
- W4381469718 hasRelatedWork W2019648073 @default.
- W4381469718 hasRelatedWork W2059481007 @default.
- W4381469718 hasRelatedWork W2399648753 @default.
- W4381469718 hasRelatedWork W3027120993 @default.
- W4381469718 hasRelatedWork W3033753898 @default.
- W4381469718 hasRelatedWork W4220737934 @default.
- W4381469718 hasRelatedWork W4253342019 @default.
- W4381469718 hasRelatedWork W4290851418 @default.
- W4381469718 isParatext "false" @default.
- W4381469718 isRetracted "false" @default.
- W4381469718 workType "article" @default.