FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4381470403> ?p ?o ?g. }

• W4381470403 abstract "High-resolution imaging has revolutionized the study of single cells in their spatial context. However, summarizing the great diversity of complex cell shapes found in tissues and inferring associations with other single-cell data remains a challenge. Here, we present CAJAL, a general computational framework for the analysis and integration of single-cell morphological data. By building upon metric geometry, CAJAL infers cell morphology latent spaces where distances between points indicate the amount of physical deformation required to change the morphology of one cell into that of another. We show that cell morphology spaces facilitate the integration of single-cell morphological data across technologies and the inference of relations with other data, such as single-cell transcriptomic data. We demonstrate the utility of CAJAL with several morphological datasets of neurons and glia and identify genes associated with neuronal plasticity in C. elegans. Our approach provides an effective strategy for integrating cell morphology data into single-cell omics analyses." @default.
• W4381470403 created "2023-06-22" @default.
• W4381470403 creator A5012930614 @default.
• W4381470403 creator A5037372907 @default.
• W4381470403 creator A5042302298 @default.
• W4381470403 creator A5055994495 @default.
• W4381470403 creator A5069589641 @default.
• W4381470403 creator A5073102843 @default.
• W4381470403 creator A5078046697 @default.
• W4381470403 creator A5080555003 @default.
• W4381470403 creator A5092222138 @default.
• W4381470403 date "2023-06-21" @default.
• W4381470403 modified "2023-09-25" @default.
• W4381470403 title "CAJAL enables analysis and integration of single-cell morphological data using metric geometry" @default.
• W4381470403 cites W1985222241 @default.
• W4381470403 cites W2027816595 @default.
• W4381470403 cites W2027842533 @default.
• W4381470403 cites W2032868343 @default.
• W4381470403 cites W2034987376 @default.
• W4381470403 cites W2036559452 @default.
• W4381470403 cites W2048962185 @default.
• W4381470403 cites W2061186544 @default.
• W4381470403 cites W2074633779 @default.
• W4381470403 cites W2107554012 @default.
• W4381470403 cites W2118376687 @default.
• W4381470403 cites W2124954099 @default.
• W4381470403 cites W2131681506 @default.
• W4381470403 cites W2147916701 @default.
• W4381470403 cites W2167279371 @default.
• W4381470403 cites W2169456326 @default.
• W4381470403 cites W2178605380 @default.
• W4381470403 cites W2198136410 @default.
• W4381470403 cites W2203450678 @default.
• W4381470403 cites W2267554996 @default.
• W4381470403 cites W2268971953 @default.
• W4381470403 cites W2279313673 @default.
• W4381470403 cites W2287328140 @default.
• W4381470403 cites W2467628122 @default.
• W4381470403 cites W2474265885 @default.
• W4381470403 cites W2510476362 @default.
• W4381470403 cites W2528382567 @default.
• W4381470403 cites W2562237609 @default.
• W4381470403 cites W2586597606 @default.
• W4381470403 cites W2601243251 @default.
• W4381470403 cites W2761733590 @default.
• W4381470403 cites W2766437506 @default.
• W4381470403 cites W2783553962 @default.
• W4381470403 cites W2799543599 @default.
• W4381470403 cites W2811106513 @default.
• W4381470403 cites W2889326414 @default.
• W4381470403 cites W2902652978 @default.
• W4381470403 cites W2949311293 @default.
• W4381470403 cites W2950976066 @default.
• W4381470403 cites W2951976236 @default.
• W4381470403 cites W2963605751 @default.
• W4381470403 cites W2991174006 @default.
• W4381470403 cites W2999309192 @default.
• W4381470403 cites W3016246634 @default.
• W4381470403 cites W3021920958 @default.
• W4381470403 cites W3033415403 @default.
• W4381470403 cites W3038192644 @default.
• W4381470403 cites W3047141442 @default.
• W4381470403 cites W3099878876 @default.
• W4381470403 cites W3101846945 @default.
• W4381470403 cites W3106117005 @default.
• W4381470403 cites W3106188259 @default.
• W4381470403 cites W3120010443 @default.
• W4381470403 cites W3148916402 @default.
• W4381470403 cites W318091530 @default.
• W4381470403 cites W3186956811 @default.
• W4381470403 cites W3202204105 @default.
• W4381470403 cites W3202358235 @default.
• W4381470403 cites W4220765701 @default.
• W4381470403 cites W3149760511 @default.
• W4381470403 doi "https://doi.org/10.1038/s41467-023-39424-2" @default.
• W4381470403 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37339989" @default.
• W4381470403 hasPublicationYear "2023" @default.
• W4381470403 type Work @default.
• W4381470403 citedByCount "0" @default.
• W4381470403 crossrefType "journal-article" @default.
• W4381470403 hasAuthorship W4381470403A5012930614 @default.
• W4381470403 hasAuthorship W4381470403A5037372907 @default.
• W4381470403 hasAuthorship W4381470403A5042302298 @default.
• W4381470403 hasAuthorship W4381470403A5055994495 @default.
• W4381470403 hasAuthorship W4381470403A5069589641 @default.
• W4381470403 hasAuthorship W4381470403A5073102843 @default.
• W4381470403 hasAuthorship W4381470403A5078046697 @default.
• W4381470403 hasAuthorship W4381470403A5080555003 @default.
• W4381470403 hasAuthorship W4381470403A5092222138 @default.
• W4381470403 hasBestOaLocation W43814704031 @default.
• W4381470403 hasConcept C104317684 @default.
• W4381470403 hasConcept C11922738 @default.
• W4381470403 hasConcept C151730666 @default.
• W4381470403 hasConcept C162324750 @default.
• W4381470403 hasConcept C176217482 @default.
• W4381470403 hasConcept C201539569 @default.
• W4381470403 hasConcept C203014093 @default.
• W4381470403 hasConcept C204232928 @default.
• W4381470403 hasConcept C21547014 @default.
• W4381470403 hasConcept C2779343474 @default.

• next