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• W4381486680 abstract "Desde el inicio de la pandemia de la COVID-19 la población mayor ha presentado las tasas más elevadas de complicaciones y mortalidad. El objetivo de este estudio fue determinar la influencia de distintos factores de riesgo sobre los fallecimientos por la variante ómicron en Canarias. Estudio observacional retrospectivo de 16.998 casos de COVID-19 en mayores de 40 años confirmados en Canarias entre el 1 agosto de 2022 y el 31 enero de 2023. Se extrajeron datos sociodemográficos (edad y sexo), clínicos (fallecimiento, vacunación, ingreso hospitalario, enfermedades previas y tratamientos). Entre los fallecidos hubo mayor proporción de varones, con edad superior a los 70 años, diabetes, enfermedad cardiovascular, renal, respiratoria y sistémica, y de residentes en centros sociosanitarios. También se encontraron diferencias significativas en cuanto al número de dosis de la vacuna. En el modelo de regresión múltiple encontramos: varón (OR [IC 95%] = 1,92 [1,42-2,58]), edad (70-79 años, 9,11 [4,27-19,43]; 80-89 años 21,72 [10,40-45,36]; 90-99 años 66,24 [31,03-141,38]; 100 años o más 69,22[12,97-369,33]) y no vacunados (6,96 [4,01-12,08]) o cuya última dosis fue administrada al menos 12 meses antes del diagnóstico (2,38 [1,48-3,81]) mostraron una asociación significativa con la mortalidad. Existen múltiples posibles factores que pueden incrementar el riesgo de mortalidad por la COVID-19 en población mayor. En nuestro estudio se ha encontrado que solo 3 predictores pueden explicar prácticamente la misma variabilidad: una edad más avanzada, el sexo varón y no estar vacunado o que la última fecha de vacunación fuese anterior a un año. Since the beginning of the COVID-19 pandemic, the elderly population has had the highest rates of complications and mortality. This study aimed to determine the influence of different risk factors on deaths due to the Omicron variant in the Canary Islands. A retrospective observational study of 16,998 cases of COVID-19 over 40 years of age was conducted in the Canary Islands between August 1, 2022, and January 31, 2023. We extracted sociodemographic data (age and sex) and clinical data (death, vaccination history, hospital admission, previous diseases, and treatments). Among the deaths, there was a higher proportion of males aged over 70 years, with diabetes, cardiovascular, renal, respiratory, and systemic diseases, and nursing home residents. Significant differences were observed in the number of doses of the vaccine. The multiple regression model showed that male sex (OR [95% CI] = 1.92 [1.42–2.58]), age (70–79 years, 9.11 [4.27–19.43]; 80–89 years, 21.72 [10.40–45.36]; 90–99 years, 66.24 [31.03–141.38]; 100 years or older, 69.22 [12.97–369.33]), being unvaccinated (6.96, [4.01–12.08]), or having the last dose administered at least 12 months before the diagnosis (2.38, [1.48–3.81]) were significantly associated with mortality. Multiple factors may increase the risk of mortality due to COVID-19 in the elderly population. In our study, we found that only three predictors can effectively explain the variability: older age, male sex, and not being vaccinated or last vaccination date prior to one year." @default.
• W4381486680 created "2023-06-22" @default.
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• W4381486680 date "2023-07-01" @default.
• W4381486680 modified "2023-09-25" @default.
• W4381486680 title "Factores de riesgo asociados a fallecimiento por la variante ómicron de COVID-19: análisis retrospectivo con personas mayores de Canarias" @default.
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• W4381486680 doi "https://doi.org/10.1016/j.regg.2023.101381" @default.
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