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- W4381489021 abstract "Catheter ablation of arrhythmias is now standard of care in invasive electrophysiology. Current ablation strategies are based on the use of thermal energy. With continuous efforts to optimize thermal energy delivery, effectiveness has greatly improved; however, safety concerns persist. This review focuses on a novel ablation technology, irreversible electroporation (IRE), also known as pulsed-field ablation which may be a safer alternative for arrhythmia management. Pulsed-field ablation is thought to be a nonthermal ablation that applies short-duration high-voltage electrical fields to ablate myocardial tissue with high selectivity and durability while sparing important neighboring structures such as the esophagus and phrenic nerves. There are multiple ongoing studies investigating the potential superior outcomes of IRE compared to radiofrequency ablation in treating patients with atrial and ventricular arrhythmias. In this review, we describe the current evidence of preclinical and clinical trials that have shown promising results of catheter-based IRE." @default.
- W4381489021 created "2023-06-22" @default.
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- W4381489021 date "2023-06-01" @default.
- W4381489021 modified "2023-10-03" @default.
- W4381489021 title "Catheter-Based Electroporation" @default.
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- W4381489021 doi "https://doi.org/10.1016/j.jacep.2023.03.014" @default.
- W4381489021 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37354168" @default.
- W4381489021 hasPublicationYear "2023" @default.
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