Matches in SemOpenAlex for { <https://semopenalex.org/work/W4381547350> ?p ?o ?g. }
- W4381547350 abstract "Bioprinting of living cells can cause major shape deformations, which may severely affect cell survival and functionality. While the shear stresses occurring during cell flow through the printer nozzle have been quantified to some extent, the extensional stresses occurring as cells leave the nozzle into the free printing strand have been mostly ignored. Here we use lattice Boltzmann simulations together with a finite-element based cell model to study cell deformation inside the nozzle and at its exit. Our simulation results are in good qualitative agreement with experimental microscopy images. We show that, for cells flowing in the center of the nozzle, extensional stresses can be significant while, for cells flowing off-center, their deformation is dominated by the shear flow inside the nozzle. From the results of these simulations, we develop two simple methods that only require the printing parameters (nozzle diameter, flow rate, bioink rheology) to (i) accurately predict the maximum cell stress occurring during the three-dimensional bioprinting process and (ii) approximately predict the cell strains caused by the elongational flow at the nozzle exit." @default.
- W4381547350 created "2023-06-22" @default.
- W4381547350 creator A5012141730 @default.
- W4381547350 creator A5038189928 @default.
- W4381547350 creator A5091177219 @default.
- W4381547350 date "2023-06-21" @default.
- W4381547350 modified "2023-09-27" @default.
- W4381547350 title "Predicting Cell Stress and Strain during Extrusion Bioprinting" @default.
- W4381547350 cites W1958673650 @default.
- W4381547350 cites W1983720999 @default.
- W4381547350 cites W1992474968 @default.
- W4381547350 cites W1994821830 @default.
- W4381547350 cites W2010165954 @default.
- W4381547350 cites W2011448168 @default.
- W4381547350 cites W2012220598 @default.
- W4381547350 cites W2016058943 @default.
- W4381547350 cites W2032325704 @default.
- W4381547350 cites W2032580187 @default.
- W4381547350 cites W2034722366 @default.
- W4381547350 cites W2039549079 @default.
- W4381547350 cites W2040278554 @default.
- W4381547350 cites W2057304403 @default.
- W4381547350 cites W2072260627 @default.
- W4381547350 cites W2084131634 @default.
- W4381547350 cites W2084196103 @default.
- W4381547350 cites W2090588873 @default.
- W4381547350 cites W2112311198 @default.
- W4381547350 cites W2145851836 @default.
- W4381547350 cites W2156311828 @default.
- W4381547350 cites W2163839106 @default.
- W4381547350 cites W2173240866 @default.
- W4381547350 cites W2182678773 @default.
- W4381547350 cites W2188090492 @default.
- W4381547350 cites W2201089622 @default.
- W4381547350 cites W2226257595 @default.
- W4381547350 cites W2513084228 @default.
- W4381547350 cites W2520718776 @default.
- W4381547350 cites W2574430960 @default.
- W4381547350 cites W2755965525 @default.
- W4381547350 cites W2789719672 @default.
- W4381547350 cites W2804416177 @default.
- W4381547350 cites W2806641818 @default.
- W4381547350 cites W2891869505 @default.
- W4381547350 cites W2893115477 @default.
- W4381547350 cites W2897597730 @default.
- W4381547350 cites W2898790114 @default.
- W4381547350 cites W2902402699 @default.
- W4381547350 cites W2905634779 @default.
- W4381547350 cites W2907485007 @default.
- W4381547350 cites W2912915283 @default.
- W4381547350 cites W2953593298 @default.
- W4381547350 cites W2956309634 @default.
- W4381547350 cites W3004843806 @default.
- W4381547350 cites W3006192259 @default.
- W4381547350 cites W3006231048 @default.
- W4381547350 cites W3025485419 @default.
- W4381547350 cites W3026721120 @default.
- W4381547350 cites W3032657203 @default.
- W4381547350 cites W3045462301 @default.
- W4381547350 cites W3047176319 @default.
- W4381547350 cites W3049691363 @default.
- W4381547350 cites W3082120244 @default.
- W4381547350 cites W3088047277 @default.
- W4381547350 cites W3088653478 @default.
- W4381547350 cites W3092810138 @default.
- W4381547350 cites W3094200587 @default.
- W4381547350 cites W3094514825 @default.
- W4381547350 cites W3102389026 @default.
- W4381547350 cites W3111647487 @default.
- W4381547350 cites W3160036498 @default.
- W4381547350 cites W3162774097 @default.
- W4381547350 cites W4239647010 @default.
- W4381547350 cites W4288035259 @default.
- W4381547350 cites W4288068477 @default.
- W4381547350 cites W4294287410 @default.
- W4381547350 cites W4297998324 @default.
- W4381547350 doi "https://doi.org/10.1103/physrevapplied.19.064061" @default.
- W4381547350 hasPublicationYear "2023" @default.
- W4381547350 type Work @default.
- W4381547350 citedByCount "0" @default.
- W4381547350 crossrefType "journal-article" @default.
- W4381547350 hasAuthorship W4381547350A5012141730 @default.
- W4381547350 hasAuthorship W4381547350A5038189928 @default.
- W4381547350 hasAuthorship W4381547350A5091177219 @default.
- W4381547350 hasBestOaLocation W43815473501 @default.
- W4381547350 hasConcept C121332964 @default.
- W4381547350 hasConcept C127313418 @default.
- W4381547350 hasConcept C127413603 @default.
- W4381547350 hasConcept C136137745 @default.
- W4381547350 hasConcept C151730666 @default.
- W4381547350 hasConcept C159985019 @default.
- W4381547350 hasConcept C192562407 @default.
- W4381547350 hasConcept C200990466 @default.
- W4381547350 hasConcept C204366326 @default.
- W4381547350 hasConcept C21141959 @default.
- W4381547350 hasConcept C21821499 @default.
- W4381547350 hasConcept C2778958987 @default.
- W4381547350 hasConcept C38349280 @default.
- W4381547350 hasConcept C56200935 @default.
- W4381547350 hasConcept C57879066 @default.