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- W4381569201 abstract "ABSTRACT A nuclear framework structure has been obtained from isolated interphase nuclei of Physarum polycephalum by extraction with 2·5 M NaCl and subsequent digestion with DNase. Wholemount electron micrographs showed a nuclear lamina containing residual pore structures associated with the fibrous internal matrix. The matrix was continuous with fibrillar remnants of the nucleolus. The structure was shown to consist of 2 major polypeptides of 23000 and 36 500 Daltons as well as 30 to 40 minor polypeptides of various molecular weight classes. The 2 major polypeptides were also prominent in preparations of the residual nucleolar material, suggesting that matrix proteins are common to both structures. The predominance of low-molecular-weight polypeptides in Physarum nuclear matrix suggests that there may be significant differences in composition of nuclear structural proteins between lower and higher eukaryotes." @default.
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- W4381569201 date "1979-10-01" @default.
- W4381569201 modified "2023-09-24" @default.
- W4381569201 title "Isolation of a residual protein structure from nuclei of the myxomycete <i>Physarum polycephalum</i>" @default.
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- W4381569201 doi "https://doi.org/10.1242/jcs.39.1.246" @default.
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