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Matches in SemOpenAlex for { <https://semopenalex.org/work/W4381597244> ?p ?o ?g. }

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• W4381597244 abstract "We developed a small MRI/NIR-II probe to target HER2 (tetanucleotide) breast cancer cells. The probe is composed of PLGA-b-PEG micelles encapsulated NIR-II, and Gd-DOTA is conjugated at the border of PLGA/PEG. Herceptin was then conjugated to carboxyl residues of PLGA-b-PEG chains. We examined the influence of carboxyl group ratios on the probe property stability and Herceptin concentration and the binding affinity to HER2(+) cells corresponding to the −COOH ratios. The binding assays demonstrated that the optimal surface ratio of −COOH is 5%, which is less affected by fluorescence reduction and which exhibited the highest antigen-capturing activity." @default.
• W4381597244 created "2023-06-23" @default.
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• W4381597244 date "2023-06-22" @default.
• W4381597244 modified "2023-09-25" @default.
• W4381597244 title "Influence of Carboxyl Group Ratios on the Design of Breast Cancer Targeting Bimodal MR/NIR-II Imaging Probe from PLGA@Gd-DOTA@PEG Micelles Conjugating Herceptin" @default.
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• W4381597244 doi "https://doi.org/10.1021/acsabm.3c00260" @default.
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