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- W4381661377 abstract "Eight lignans (1-8) and two macrolides (9-10) were isolated from the CHCl₃-soluble fraction of Houttuynia cordata Thumb (Saururaceae). Structures of isolates were elucidated by extensive spectroscopic methods. Fatty acid-derived macrolides (9-10) have rarely been reported from nature. All the isolates were tested for their inhibitory activities against NO production in RAW 264.7 cells stimulated by LPS. It was found that compounds 3 and 9 remarkably down-regulated LPS-induced NO production with IC50 values, 5.4 and 40.3 μM, respectively, without cytotoxicity." @default.
- W4381661377 created "2023-06-23" @default.
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- W4381661377 date "2022-03-31" @default.
- W4381661377 modified "2023-10-16" @default.
- W4381661377 title "Lignans and Macrolides from the Leaves of Houttuynia cordata with Inhibitory Activity against NO Production in Murine Macrophage RAW 264.7 Cells" @default.
- W4381661377 doi "https://doi.org/10.20307/nps.2022.28.1.33" @default.
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