FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4381661837> ?p ?o ?g. }

• W4381661837 abstract "Background Physical activity is a modifiable lifestyle factor that has been previously associated with reduced vascular burden and reduced risk of dementia. Objectives This study tested whether physical activity (i.e., being inactive vs. active) contributed to preservation of white matter microstructure in healthy aging controls and patients in prodromal to mild Alzheimer’s disease with low/high vascular burden. Materials A total of 213 participants were recruited from memory clinics. They were classified as being either physically active ( n = 113) or inactive ( n = 100) based on the Cardiovascular Risk Factors, Aging and Dementia (CAIDE) questionnaire. Diffusion-weighted images were acquired for all participants and pre-processed based on a standard protocol. Methods A factorial design using voxel-wise tract-based spatial statistics (TBSS) was adopted, with 5,000 permutations and threshold-free cluster enhancement (TFCE), to identify significant clusters for fractional anisotropy (FA), axial diffusivity (AxD), mean diffusivity (MD), and radial diffusivity (RD). Results Clusters of higher FA and lower AxD, MD, and RD values were found for physically active compared with inactive participants that were widespread covering mainly association and projection tracts but also some commissural tracts. A three-way Group × Physical Activity × Vascular Burden interaction effect was found for FA mostly in a variety of projection tracts with a right predominance, and some commissural and association tracts. Post hoc analyses revealed higher FA in patients with high vascular burden who were physically active compared with those patients with high vascular burden who were inactive mainly in projection and association/limbic tracts with a right predominance. Additionally, higher FA was observed in physically active patients with high vascular burden as compared with physically inactive controls with high vascular burden, mainly in bilateral projection fibers and cerebellar regions. Conclusion Voxel-wise TBSS analysis revealed better preservation of white matter microstructure that was prominent in the high-risk group such as the patients with high vascular burden, specifically those who were physically active. The beneficial effects of physical activity on white matter microstructure were not observed in the controls." @default.
• W4381661837 created "2023-06-23" @default.
• W4381661837 creator A5046521053 @default.
• W4381661837 creator A5075445831 @default.
• W4381661837 creator A5079862221 @default.
• W4381661837 creator A5089820600 @default.
• W4381661837 creator A5091517356 @default.
• W4381661837 date "2023-06-21" @default.
• W4381661837 modified "2023-10-18" @default.
• W4381661837 title "The effect of physical activity on white matter integrity in aging and prodromal to mild Alzheimer’s disease with vascular comorbidity" @default.
• W4381661837 cites W1095226386 @default.
• W4381661837 cites W1880579033 @default.
• W4381661837 cites W1964997677 @default.
• W4381661837 cites W1994972002 @default.
• W4381661837 cites W2004006028 @default.
• W4381661837 cites W2004757203 @default.
• W4381661837 cites W2006096283 @default.
• W4381661837 cites W2009869050 @default.
• W4381661837 cites W2028748733 @default.
• W4381661837 cites W2034897558 @default.
• W4381661837 cites W2036289317 @default.
• W4381661837 cites W2045407457 @default.
• W4381661837 cites W2046557060 @default.
• W4381661837 cites W2071881327 @default.
• W4381661837 cites W2074572113 @default.
• W4381661837 cites W2081237186 @default.
• W4381661837 cites W2086335976 @default.
• W4381661837 cites W2094941678 @default.
• W4381661837 cites W2095965187 @default.
• W4381661837 cites W2096645624 @default.
• W4381661837 cites W2098706789 @default.
• W4381661837 cites W2103351609 @default.
• W4381661837 cites W2105024128 @default.
• W4381661837 cites W2106159603 @default.
• W4381661837 cites W2115017507 @default.
• W4381661837 cites W2122522567 @default.
• W4381661837 cites W2125657871 @default.
• W4381661837 cites W2126693856 @default.
• W4381661837 cites W2147243367 @default.
• W4381661837 cites W2148092884 @default.
• W4381661837 cites W2148828979 @default.
• W4381661837 cites W2150667092 @default.
• W4381661837 cites W2164037272 @default.
• W4381661837 cites W2169366712 @default.
• W4381661837 cites W2358666620 @default.
• W4381661837 cites W2468595961 @default.
• W4381661837 cites W2582524520 @default.
• W4381661837 cites W2774321631 @default.
• W4381661837 cites W2793043361 @default.
• W4381661837 cites W2907477685 @default.
• W4381661837 cites W2910571127 @default.
• W4381661837 cites W2937543516 @default.
• W4381661837 cites W2994328771 @default.
• W4381661837 cites W3046275966 @default.
• W4381661837 cites W3084734848 @default.
• W4381661837 cites W3095442182 @default.
• W4381661837 cites W3096357247 @default.
• W4381661837 cites W3116565824 @default.
• W4381661837 cites W3159290276 @default.
• W4381661837 cites W3161301064 @default.
• W4381661837 cites W3216484816 @default.
• W4381661837 cites W4221122151 @default.
• W4381661837 cites W4224003362 @default.
• W4381661837 cites W4226303291 @default.
• W4381661837 doi "https://doi.org/10.3389/fnagi.2023.1096798" @default.
• W4381661837 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37520122" @default.
• W4381661837 hasPublicationYear "2023" @default.
• W4381661837 type Work @default.
• W4381661837 citedByCount "0" @default.
• W4381661837 crossrefType "journal-article" @default.
• W4381661837 hasAuthorship W4381661837A5046521053 @default.
• W4381661837 hasAuthorship W4381661837A5075445831 @default.
• W4381661837 hasAuthorship W4381661837A5079862221 @default.
• W4381661837 hasAuthorship W4381661837A5089820600 @default.
• W4381661837 hasAuthorship W4381661837A5091517356 @default.
• W4381661837 hasBestOaLocation W43816618371 @default.
• W4381661837 hasConcept C126322002 @default.
• W4381661837 hasConcept C126838900 @default.
• W4381661837 hasConcept C127413603 @default.
• W4381661837 hasConcept C143409427 @default.
• W4381661837 hasConcept C149550507 @default.
• W4381661837 hasConcept C15744967 @default.
• W4381661837 hasConcept C164705383 @default.
• W4381661837 hasConcept C2777952318 @default.
• W4381661837 hasConcept C2779134260 @default.
• W4381661837 hasConcept C2779159551 @default.
• W4381661837 hasConcept C2779483572 @default.
• W4381661837 hasConcept C2780645631 @default.
• W4381661837 hasConcept C2781192897 @default.
• W4381661837 hasConcept C71924100 @default.
• W4381661837 hasConcept C78519656 @default.
• W4381661837 hasConcept C89916169 @default.
• W4381661837 hasConceptScore W4381661837C126322002 @default.
• W4381661837 hasConceptScore W4381661837C126838900 @default.
• W4381661837 hasConceptScore W4381661837C127413603 @default.
• W4381661837 hasConceptScore W4381661837C143409427 @default.
• W4381661837 hasConceptScore W4381661837C149550507 @default.
• W4381661837 hasConceptScore W4381661837C15744967 @default.
• W4381661837 hasConceptScore W4381661837C164705383 @default.
• W4381661837 hasConceptScore W4381661837C2777952318 @default.

• next