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- W4381663191 endingPage "1422" @default.
- W4381663191 startingPage "1422" @default.
- W4381663191 abstract "Haematological (blood) cancers are the cancers of the blood and lymphoid forming tissues which represents approximately 10% of all cancers. It has been reported that approximately 60% of all blood cancers are incurable. Despite substantial improvement in access to detection/diagnosis, chemotherapy and bone marrow transplantation, there is still high recurrence and unpredictable but clearly defined relapses indicating that effective therapies are still lacking. Over the past two decades, medicinal plants and their biologically active compounds are being used as potential remedies and alternative therapies for the treatment of cancer. This is due to their anti-oxidant, anti-inflammatory, anti-mutagenic, anti-angiogenic, anti-cancer activities and negligible side effects. These bioactive compounds have the capacity to reduce proliferation of haematological cancers via various mechanisms such as promoting apoptosis, transcription regulation, inhibition of signalling pathways, downregulating receptors and blocking cell cycle. This review study highlights the mechanistic and beneficial effects of nine bioactive compounds (quercetin, ursolic acid, fisetin, resveratrol, epigallocatechin gallate, curcumin, gambogic acid, butein and celastrol) as potential remedies for chemoprevention of haematological cancers. The study provides useful insights on the effectiveness of the use of bioactive compounds from plants for chemoprevention of haematological cancers." @default.
- W4381663191 created "2023-06-23" @default.
- W4381663191 creator A5036884780 @default.
- W4381663191 creator A5071865860 @default.
- W4381663191 creator A5074145056 @default.
- W4381663191 creator A5085597752 @default.
- W4381663191 date "2023-06-21" @default.
- W4381663191 modified "2023-10-05" @default.
- W4381663191 title "Bioactive Phytoconstituents and Their Therapeutic Potentials in the Treatment of Haematological Cancers: A Review" @default.
- W4381663191 cites W1235280006 @default.
- W4381663191 cites W1518516100 @default.
- W4381663191 cites W1587528990 @default.
- W4381663191 cites W1879303052 @default.
- W4381663191 cites W1898811823 @default.
- W4381663191 cites W1919662197 @default.
- W4381663191 cites W1927915280 @default.
- W4381663191 cites W1964420304 @default.
- W4381663191 cites W1968826816 @default.
- W4381663191 cites W1969747282 @default.
- W4381663191 cites W1969819976 @default.
- W4381663191 cites W1971062590 @default.
- W4381663191 cites W1975928613 @default.
- W4381663191 cites W1977258127 @default.
- W4381663191 cites W1979401674 @default.
- W4381663191 cites W1979658752 @default.
- W4381663191 cites W1981699944 @default.
- W4381663191 cites W1985235736 @default.
- W4381663191 cites W1993334239 @default.
- W4381663191 cites W1994682335 @default.
- W4381663191 cites W1995844463 @default.
- W4381663191 cites W1996712795 @default.
- W4381663191 cites W1996982049 @default.
- W4381663191 cites W2000209753 @default.
- W4381663191 cites W2001839572 @default.
- W4381663191 cites W2003892126 @default.
- W4381663191 cites W2005115307 @default.
- W4381663191 cites W2005205810 @default.
- W4381663191 cites W2008757142 @default.
- W4381663191 cites W2011202048 @default.
- W4381663191 cites W2017821950 @default.
- W4381663191 cites W2018182375 @default.
- W4381663191 cites W2020221926 @default.
- W4381663191 cites W2021927100 @default.
- W4381663191 cites W2023650157 @default.
- W4381663191 cites W2025922671 @default.
- W4381663191 cites W2028661295 @default.
- W4381663191 cites W2030329058 @default.
- W4381663191 cites W2035101957 @default.
- W4381663191 cites W2036380534 @default.
- W4381663191 cites W2040191245 @default.
- W4381663191 cites W2041544048 @default.
- W4381663191 cites W2052828768 @default.
- W4381663191 cites W2054553710 @default.
- W4381663191 cites W2062155176 @default.
- W4381663191 cites W2063299574 @default.
- W4381663191 cites W2066991013 @default.
- W4381663191 cites W2067891488 @default.
- W4381663191 cites W2069664794 @default.
- W4381663191 cites W2076961989 @default.
- W4381663191 cites W2078317560 @default.
- W4381663191 cites W2090454469 @default.
- W4381663191 cites W2090464175 @default.
- W4381663191 cites W2091627272 @default.
- W4381663191 cites W2091704205 @default.
- W4381663191 cites W2093149339 @default.
- W4381663191 cites W2093157946 @default.
- W4381663191 cites W2095142150 @default.
- W4381663191 cites W2102470188 @default.
- W4381663191 cites W2102654658 @default.
- W4381663191 cites W2106651240 @default.
- W4381663191 cites W2117510998 @default.
- W4381663191 cites W2117747115 @default.
- W4381663191 cites W2118331143 @default.
- W4381663191 cites W2119576166 @default.
- W4381663191 cites W2123464171 @default.
- W4381663191 cites W2124789340 @default.
- W4381663191 cites W2125023824 @default.
- W4381663191 cites W2125552828 @default.
- W4381663191 cites W2125961046 @default.
- W4381663191 cites W2129911513 @default.
- W4381663191 cites W2131521607 @default.
- W4381663191 cites W2131550376 @default.
- W4381663191 cites W2134243435 @default.
- W4381663191 cites W2137883403 @default.
- W4381663191 cites W2138342044 @default.
- W4381663191 cites W2140865442 @default.
- W4381663191 cites W2141322180 @default.
- W4381663191 cites W2144728882 @default.
- W4381663191 cites W2151371056 @default.
- W4381663191 cites W2151684406 @default.
- W4381663191 cites W2153478782 @default.
- W4381663191 cites W2160675185 @default.
- W4381663191 cites W2167826964 @default.
- W4381663191 cites W2170420350 @default.
- W4381663191 cites W2182560414 @default.
- W4381663191 cites W2190924685 @default.
- W4381663191 cites W2192386755 @default.
- W4381663191 cites W2199776754 @default.