Matches in SemOpenAlex for { <https://semopenalex.org/work/W4381664374> ?p ?o ?g. }
- W4381664374 endingPage "1297" @default.
- W4381664374 startingPage "1297" @default.
- W4381664374 abstract "Psoriasis is a chronic inflammatory skin disease characterized by the appearance of clearly demarcated erythematous and scaly plaques. It can be divided into various types, including plaque, nail, guttate, inverse, and pustular psoriasis. Plaque psoriasis is the most commonly occurring type, though there is another rare but severe pustular autoinflammatory skin disease called generalized pustular psoriasis (GPP), which manifests with acute episodes of pustulation and systemic symptoms. Though the etiopathogenesis of psoriasis is not yet fully understood, a growing body of literature has demonstrated that both genetic and environmental factors play a role. The discovery of genetic mutations associated with GPP has shed light on our comprehension of the mechanisms of the disease, promoting the development of targeted therapies. This review will summarize genetic determinants as known and provide an update on the current and potential treatments for GPP. The pathogenesis and clinical presentation of the disease are also included for a comprehensive discussion." @default.
- W4381664374 created "2023-06-23" @default.
- W4381664374 creator A5009007964 @default.
- W4381664374 creator A5011123078 @default.
- W4381664374 creator A5011404334 @default.
- W4381664374 creator A5013960155 @default.
- W4381664374 creator A5017009555 @default.
- W4381664374 creator A5071411059 @default.
- W4381664374 creator A5075946037 @default.
- W4381664374 date "2023-06-20" @default.
- W4381664374 modified "2023-09-29" @default.
- W4381664374 title "Genetics of Generalized Pustular Psoriasis: Current Understanding and Implications for Future Therapeutics" @default.
- W4381664374 cites W1573229632 @default.
- W4381664374 cites W1969908901 @default.
- W4381664374 cites W1991098806 @default.
- W4381664374 cites W2000849614 @default.
- W4381664374 cites W2041437482 @default.
- W4381664374 cites W2044350486 @default.
- W4381664374 cites W2045015441 @default.
- W4381664374 cites W2068737062 @default.
- W4381664374 cites W2070481847 @default.
- W4381664374 cites W2074547696 @default.
- W4381664374 cites W2084757225 @default.
- W4381664374 cites W2095667188 @default.
- W4381664374 cites W2112698713 @default.
- W4381664374 cites W2160997906 @default.
- W4381664374 cites W2279719049 @default.
- W4381664374 cites W2336283515 @default.
- W4381664374 cites W2468433846 @default.
- W4381664374 cites W2514982855 @default.
- W4381664374 cites W2530872160 @default.
- W4381664374 cites W2565131287 @default.
- W4381664374 cites W2642432975 @default.
- W4381664374 cites W2729992889 @default.
- W4381664374 cites W2749040829 @default.
- W4381664374 cites W2762592199 @default.
- W4381664374 cites W2763258982 @default.
- W4381664374 cites W2767770641 @default.
- W4381664374 cites W2780312940 @default.
- W4381664374 cites W2802590698 @default.
- W4381664374 cites W2802954973 @default.
- W4381664374 cites W2883167586 @default.
- W4381664374 cites W2890431055 @default.
- W4381664374 cites W2899481952 @default.
- W4381664374 cites W2921399822 @default.
- W4381664374 cites W2953454230 @default.
- W4381664374 cites W2982353387 @default.
- W4381664374 cites W2999718732 @default.
- W4381664374 cites W3004526292 @default.
- W4381664374 cites W3010975180 @default.
- W4381664374 cites W3028355101 @default.
- W4381664374 cites W3040081948 @default.
- W4381664374 cites W3047228509 @default.
- W4381664374 cites W3047598936 @default.
- W4381664374 cites W3064743682 @default.
- W4381664374 cites W3092092411 @default.
- W4381664374 cites W3153722217 @default.
- W4381664374 cites W3157161163 @default.
- W4381664374 cites W3158951132 @default.
- W4381664374 cites W3160096338 @default.
- W4381664374 cites W3162635687 @default.
- W4381664374 cites W3189773998 @default.
- W4381664374 cites W3191528847 @default.
- W4381664374 cites W3203823368 @default.
- W4381664374 cites W3204485189 @default.
- W4381664374 cites W3207173999 @default.
- W4381664374 cites W3216982482 @default.
- W4381664374 cites W4200335722 @default.
- W4381664374 cites W4200421636 @default.
- W4381664374 cites W4200454679 @default.
- W4381664374 cites W4205426047 @default.
- W4381664374 cites W4205532092 @default.
- W4381664374 cites W4206436420 @default.
- W4381664374 cites W4206739528 @default.
- W4381664374 cites W4207039412 @default.
- W4381664374 cites W4214543054 @default.
- W4381664374 cites W4220654787 @default.
- W4381664374 cites W4223594625 @default.
- W4381664374 cites W4225992562 @default.
- W4381664374 cites W4226394802 @default.
- W4381664374 cites W4285122081 @default.
- W4381664374 cites W4287219590 @default.
- W4381664374 cites W4294668113 @default.
- W4381664374 cites W4307228134 @default.
- W4381664374 cites W4312838875 @default.
- W4381664374 cites W4313340259 @default.
- W4381664374 cites W4313362279 @default.
- W4381664374 cites W4317609707 @default.
- W4381664374 cites W4320482110 @default.
- W4381664374 cites W4321116988 @default.
- W4381664374 cites W4322765827 @default.
- W4381664374 cites W4328049137 @default.
- W4381664374 cites W4367553238 @default.
- W4381664374 doi "https://doi.org/10.3390/genes14061297" @default.
- W4381664374 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37372477" @default.
- W4381664374 hasPublicationYear "2023" @default.
- W4381664374 type Work @default.
- W4381664374 citedByCount "0" @default.