Matches in SemOpenAlex for { <https://semopenalex.org/work/W4381679435> ?p ?o ?g. }
Showing items 1 to 49 of
49
with 100 items per page.
- W4381679435 abstract "Alzheimer’s disease (AD) is a typical neurodegenerative disease. [Formula: see text]-amyloid (A[Formula: see text] plaque is the most prominent pathological biomarker associated with the progression of AD. Conventional A[Formula: see text] probes, including commercial probe ThT, usually suffer from tedious washing procedures. Herein, novel AIE-active A[Formula: see text] probes with excellent water solubility, named DE-V1-PYC3 and DE-V1-PYOH, were developed for the detection and image of A[Formula: see text] without tedious washing procedures. Compared with commercial probe ThT, the AIE-active A[Formula: see text] probes exhibited better sensitivity and affinity to A[Formula: see text] aggregates. Moreover, for ThT, the washing procedures are essential to obtain high signal-to-noise ratio (SNR) images of A[Formula: see text] plaques in AD brain tissue slices. DE-V1-PYC3 and DE-V1-PYOH can label A[Formula: see text] plaques in AD brain tissue slices with high SNR even without tedious washing procedures." @default.
- W4381679435 created "2023-06-23" @default.
- W4381679435 creator A5031038071 @default.
- W4381679435 creator A5031653853 @default.
- W4381679435 creator A5045309022 @default.
- W4381679435 creator A5047968661 @default.
- W4381679435 creator A5071274204 @default.
- W4381679435 date "2023-06-10" @default.
- W4381679435 modified "2023-10-13" @default.
- W4381679435 title "Development of water-soluble AIE-based wash-free Aβ probes superior to commercial ThT" @default.
- W4381679435 doi "https://doi.org/10.1142/s1793545823300094" @default.
- W4381679435 hasPublicationYear "2023" @default.
- W4381679435 type Work @default.
- W4381679435 citedByCount "0" @default.
- W4381679435 crossrefType "journal-article" @default.
- W4381679435 hasAuthorship W4381679435A5031038071 @default.
- W4381679435 hasAuthorship W4381679435A5031653853 @default.
- W4381679435 hasAuthorship W4381679435A5045309022 @default.
- W4381679435 hasAuthorship W4381679435A5047968661 @default.
- W4381679435 hasAuthorship W4381679435A5071274204 @default.
- W4381679435 hasBestOaLocation W43816794351 @default.
- W4381679435 hasConcept C136229726 @default.
- W4381679435 hasConcept C185592680 @default.
- W4381679435 hasConcept C2986936838 @default.
- W4381679435 hasConcept C41008148 @default.
- W4381679435 hasConcept C71924100 @default.
- W4381679435 hasConceptScore W4381679435C136229726 @default.
- W4381679435 hasConceptScore W4381679435C185592680 @default.
- W4381679435 hasConceptScore W4381679435C2986936838 @default.
- W4381679435 hasConceptScore W4381679435C41008148 @default.
- W4381679435 hasConceptScore W4381679435C71924100 @default.
- W4381679435 hasFunder F4320321001 @default.
- W4381679435 hasFunder F4320335777 @default.
- W4381679435 hasLocation W43816794351 @default.
- W4381679435 hasOpenAccess W4381679435 @default.
- W4381679435 hasPrimaryLocation W43816794351 @default.
- W4381679435 hasRelatedWork W1497548366 @default.
- W4381679435 hasRelatedWork W1510964613 @default.
- W4381679435 hasRelatedWork W2003823156 @default.
- W4381679435 hasRelatedWork W2293392226 @default.
- W4381679435 hasRelatedWork W2523137079 @default.
- W4381679435 hasRelatedWork W2748952813 @default.
- W4381679435 hasRelatedWork W2899084033 @default.
- W4381679435 hasRelatedWork W2946018793 @default.
- W4381679435 hasRelatedWork W3166566511 @default.
- W4381679435 hasRelatedWork W4206524032 @default.
- W4381679435 isParatext "false" @default.
- W4381679435 isRetracted "false" @default.
- W4381679435 workType "article" @default.