FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4381715511> ?p ?o ?g. }

• W4381715511 endingPage "150" @default.
• W4381715511 startingPage "144" @default.
• W4381715511 abstract "Purpose To investigate the toxicity of repeated simultaneous intrastromal and intracameral injections of voriconazole in corneal endothelial cells in a rabbit model.Methods Thirty-six eyes of 18 New Zealand white rabbits (six eyes per group) were divided into 6 groups according to the concentration of voriconazole (Group A, 0%; Group B, 0.05%; Group C, 0.1%; Group D, 0.25%; Group E, 0.5%; Group F, 1%). A combination of intrastromal and intracameral voriconazole injections were administrated to the eyes of each group three times on days 0, 3, and 7. Corneal clouding grades and central corneal thickness (CCT) were examined on days 0, 3, 7, 10, and 14. The endothelial cell counts (ECC) were measured on days 0 and 14. Scanning electron microscopy (SEM) and transmission electron microscopy (TEM) were performed on day 14.Results Group F (1%) showed more severe corneal clouding than the other groups (Groups A–E) from day 7 (p < 0.05, respectively). There were no significant differences in CCT and ECC among the six groups at any time point (p > 0.05, respectively). SEM revealed blurring of the cell border and loss of microvilli at concentrations ≥0.25% (Groups D–F). TEM revealed microstructural changes in endothelial cells at concentrations ≥0.1% (Groups C–F), and multiple vacuoles were observed at a concentration of 1% voriconazole (Group F).Conclusions Repeated simultaneous intrastromal and intracameral voriconazole injections at a concentration of 0.1% or higher induced microstructural endothelial damage in rabbit corneal endothelial cells." @default.
• W4381715511 created "2023-06-24" @default.
• W4381715511 creator A5014712462 @default.
• W4381715511 creator A5016070679 @default.
• W4381715511 creator A5057445570 @default.
• W4381715511 creator A5066443718 @default.
• W4381715511 date "2023-06-23" @default.
• W4381715511 modified "2023-10-16" @default.
• W4381715511 title "Toxicity of simultaneous intrastromal and intracameral injection of voriconazole on corneal endothelium in a rabbit model" @default.
• W4381715511 cites W1975650927 @default.
• W4381715511 cites W1985104966 @default.
• W4381715511 cites W2001434845 @default.
• W4381715511 cites W2010870969 @default.
• W4381715511 cites W2013000822 @default.
• W4381715511 cites W2022030316 @default.
• W4381715511 cites W2062103118 @default.
• W4381715511 cites W2062329228 @default.
• W4381715511 cites W2062661267 @default.
• W4381715511 cites W2073377576 @default.
• W4381715511 cites W2076379908 @default.
• W4381715511 cites W2090702657 @default.
• W4381715511 cites W2098256719 @default.
• W4381715511 cites W2103513863 @default.
• W4381715511 cites W2111283351 @default.
• W4381715511 cites W2123709249 @default.
• W4381715511 cites W2135215253 @default.
• W4381715511 cites W2135934834 @default.
• W4381715511 cites W2139076184 @default.
• W4381715511 cites W2140002018 @default.
• W4381715511 cites W2147141118 @default.
• W4381715511 cites W2151110605 @default.
• W4381715511 cites W2152698132 @default.
• W4381715511 cites W2158343182 @default.
• W4381715511 cites W2160420092 @default.
• W4381715511 cites W2163099413 @default.
• W4381715511 cites W2297075820 @default.
• W4381715511 cites W2314681583 @default.
• W4381715511 cites W2322864170 @default.
• W4381715511 cites W2333885542 @default.
• W4381715511 cites W2338045707 @default.
• W4381715511 cites W2407547081 @default.
• W4381715511 cites W2605518749 @default.
• W4381715511 cites W2751025287 @default.
• W4381715511 cites W2753318407 @default.
• W4381715511 cites W2767031614 @default.
• W4381715511 cites W2910390683 @default.
• W4381715511 cites W2994706875 @default.
• W4381715511 cites W3008623778 @default.
• W4381715511 cites W3094023869 @default.
• W4381715511 cites W3186797827 @default.
• W4381715511 cites W3190973385 @default.
• W4381715511 cites W3208072175 @default.
• W4381715511 cites W4200075298 @default.
• W4381715511 cites W4237275920 @default.
• W4381715511 cites W767486014 @default.
• W4381715511 doi "https://doi.org/10.1080/15569527.2023.2226714" @default.
• W4381715511 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37350680" @default.
• W4381715511 hasPublicationYear "2023" @default.
• W4381715511 type Work @default.
• W4381715511 citedByCount "0" @default.
• W4381715511 crossrefType "journal-article" @default.
• W4381715511 hasAuthorship W4381715511A5014712462 @default.
• W4381715511 hasAuthorship W4381715511A5016070679 @default.
• W4381715511 hasAuthorship W4381715511A5057445570 @default.
• W4381715511 hasAuthorship W4381715511A5066443718 @default.
• W4381715511 hasConcept C118487528 @default.
• W4381715511 hasConcept C126322002 @default.
• W4381715511 hasConcept C151730666 @default.
• W4381715511 hasConcept C16005928 @default.
• W4381715511 hasConcept C16685009 @default.
• W4381715511 hasConcept C185592680 @default.
• W4381715511 hasConcept C2775901793 @default.
• W4381715511 hasConcept C2776882836 @default.
• W4381715511 hasConcept C2779548794 @default.
• W4381715511 hasConcept C2780690907 @default.
• W4381715511 hasConcept C2780886939 @default.
• W4381715511 hasConcept C29730261 @default.
• W4381715511 hasConcept C71924100 @default.
• W4381715511 hasConcept C86803240 @default.
• W4381715511 hasConceptScore W4381715511C118487528 @default.
• W4381715511 hasConceptScore W4381715511C126322002 @default.
• W4381715511 hasConceptScore W4381715511C151730666 @default.
• W4381715511 hasConceptScore W4381715511C16005928 @default.
• W4381715511 hasConceptScore W4381715511C16685009 @default.
• W4381715511 hasConceptScore W4381715511C185592680 @default.
• W4381715511 hasConceptScore W4381715511C2775901793 @default.
• W4381715511 hasConceptScore W4381715511C2776882836 @default.
• W4381715511 hasConceptScore W4381715511C2779548794 @default.
• W4381715511 hasConceptScore W4381715511C2780690907 @default.
• W4381715511 hasConceptScore W4381715511C2780886939 @default.
• W4381715511 hasConceptScore W4381715511C29730261 @default.
• W4381715511 hasConceptScore W4381715511C71924100 @default.
• W4381715511 hasConceptScore W4381715511C86803240 @default.
• W4381715511 hasIssue "3" @default.
• W4381715511 hasLocation W43817155111 @default.
• W4381715511 hasLocation W43817155112 @default.
• W4381715511 hasOpenAccess W4381715511 @default.
• W4381715511 hasPrimaryLocation W43817155111 @default.

• next