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• W4381887238 startingPage "156280" @default.
• W4381887238 abstract "To investigate the clinical significance of serum cytokine profiles for differentiating between Kawasaki disease (KD) and its mimickers.Patients with KD, including complete KD, KD shock syndrome (KDSS), and KD with macrophage activation syndrome (KD-MAS), and its mimickers, including multisystem inflammatory syndrome in children, toxic shock syndrome, and Yersinia pseudotuberculosis infection, were enrolled. Serum levels of interleukin (IL)-6, soluble tumor necrosis factor receptor type II (sTNF-RII), IL-10, IL-18, and chemokine (C-X-C motif) ligand 9 (CXCL9) were measured using enzyme-linked immunosorbent assay and compared them with clinical manifestations.Serum IL-6, sTNF-RII, and IL-10 levels were significantly elevated in patients with KDSS. Serum IL-18 levels were substantially elevated in patients with KD-MAS. Patients with KD-MAS and KD mimickers had significantly elevated serum CXCL9 levels compared with those with complete KD. Area under the receiver operating characteristic curve analysis showed that serum IL-6 was the most useful for differentiating KDSS from the others, IL-18 and CXCL9 for KD-MAS from complete KD, and CXCL9 for KD mimickers from complete KD and KD-MAS.Serum cytokine profiles may be useful for differentiating between KD and its mimickers." @default.
• W4381887238 created "2023-06-25" @default.
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• W4381887238 date "2023-09-01" @default.
• W4381887238 modified "2023-10-16" @default.
• W4381887238 title "Clinical significance of serum cytokine profiles for differentiating between Kawasaki disease and its mimickers" @default.
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• W4381887238 doi "https://doi.org/10.1016/j.cyto.2023.156280" @default.
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