Matches in SemOpenAlex for { <https://semopenalex.org/work/W4381892016> ?p ?o ?g. }
Showing items 1 to 67 of
67
with 100 items per page.
- W4381892016 abstract "Abstract Background: Dosimetry-based personalized therapy was shown to have clinical benefits e.g. in liver selective internal radiation therapy (SIRT). Yet, there is no consensus about its introduction into clinical practice, mainly as Monte Carlo simulations (gold standard for dosimetry) involve massive computation time. We addressed the problem of computation time and tested a patch-based approach for Monte Carlo simulations for internal dosimetry to improve parallelization. We introduce a physics-inspired cropping layout for patch-based MC dosimetry, and compare it to cropping layouts of the literature as well as dosimetry using organ-S-values, and dose kernels, taking whole-body Monte Carlo simulations as ground truth. This was evaluated in five patients receiving Yttrium-90 liver SIRT. Results: The patch-based Monte Carlo approach yielded the closest results to the ground truth, making it a valid alternative to the conventional approach. Our physics-inspired cropping layout and mosaicking scheme yielded a voxel-wise error of ≈ 3% compared to whole-body Monte Carlo in soft tissue, while requiring only ≈ 10% of the time. Conclusions: This work demonstrates the feasibility and accuracy of physics-inspired cropping layouts for patch-based Monte Carlo simulations." @default.
- W4381892016 created "2023-06-25" @default.
- W4381892016 creator A5010198696 @default.
- W4381892016 creator A5011729018 @default.
- W4381892016 creator A5014516945 @default.
- W4381892016 creator A5046896448 @default.
- W4381892016 creator A5067941796 @default.
- W4381892016 creator A5077969822 @default.
- W4381892016 creator A5092254255 @default.
- W4381892016 date "2023-06-23" @default.
- W4381892016 modified "2023-09-25" @default.
- W4381892016 title "DosePatch: Physics-Inspired cropping layout for Patch-based Monte Carlo simulations to provide fast and accurate internal dosimetry" @default.
- W4381892016 doi "https://doi.org/10.21203/rs.3.rs-3044724/v1" @default.
- W4381892016 hasPublicationYear "2023" @default.
- W4381892016 type Work @default.
- W4381892016 citedByCount "0" @default.
- W4381892016 crossrefType "posted-content" @default.
- W4381892016 hasAuthorship W4381892016A5010198696 @default.
- W4381892016 hasAuthorship W4381892016A5011729018 @default.
- W4381892016 hasAuthorship W4381892016A5014516945 @default.
- W4381892016 hasAuthorship W4381892016A5046896448 @default.
- W4381892016 hasAuthorship W4381892016A5067941796 @default.
- W4381892016 hasAuthorship W4381892016A5077969822 @default.
- W4381892016 hasAuthorship W4381892016A5092254255 @default.
- W4381892016 hasBestOaLocation W43818920161 @default.
- W4381892016 hasConcept C105795698 @default.
- W4381892016 hasConcept C11413529 @default.
- W4381892016 hasConcept C121332964 @default.
- W4381892016 hasConcept C154945302 @default.
- W4381892016 hasConcept C19499675 @default.
- W4381892016 hasConcept C19527891 @default.
- W4381892016 hasConcept C2989005 @default.
- W4381892016 hasConcept C33923547 @default.
- W4381892016 hasConcept C41008148 @default.
- W4381892016 hasConcept C45374587 @default.
- W4381892016 hasConcept C54170458 @default.
- W4381892016 hasConcept C71924100 @default.
- W4381892016 hasConcept C75088862 @default.
- W4381892016 hasConceptScore W4381892016C105795698 @default.
- W4381892016 hasConceptScore W4381892016C11413529 @default.
- W4381892016 hasConceptScore W4381892016C121332964 @default.
- W4381892016 hasConceptScore W4381892016C154945302 @default.
- W4381892016 hasConceptScore W4381892016C19499675 @default.
- W4381892016 hasConceptScore W4381892016C19527891 @default.
- W4381892016 hasConceptScore W4381892016C2989005 @default.
- W4381892016 hasConceptScore W4381892016C33923547 @default.
- W4381892016 hasConceptScore W4381892016C41008148 @default.
- W4381892016 hasConceptScore W4381892016C45374587 @default.
- W4381892016 hasConceptScore W4381892016C54170458 @default.
- W4381892016 hasConceptScore W4381892016C71924100 @default.
- W4381892016 hasConceptScore W4381892016C75088862 @default.
- W4381892016 hasLocation W43818920161 @default.
- W4381892016 hasOpenAccess W4381892016 @default.
- W4381892016 hasPrimaryLocation W43818920161 @default.
- W4381892016 hasRelatedWork W1789506614 @default.
- W4381892016 hasRelatedWork W1976011493 @default.
- W4381892016 hasRelatedWork W2045815051 @default.
- W4381892016 hasRelatedWork W2056268766 @default.
- W4381892016 hasRelatedWork W2059998698 @default.
- W4381892016 hasRelatedWork W2068687282 @default.
- W4381892016 hasRelatedWork W2107060987 @default.
- W4381892016 hasRelatedWork W2609018911 @default.
- W4381892016 hasRelatedWork W3047694216 @default.
- W4381892016 hasRelatedWork W3193455909 @default.
- W4381892016 isParatext "false" @default.
- W4381892016 isRetracted "false" @default.
- W4381892016 workType "article" @default.