FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4381954767> ?p ?o ?g. }

• W4381954767 endingPage "222" @default.
• W4381954767 startingPage "205" @default.
• W4381954767 abstract "The gut microbiome has been found to influence diseases of the gastrointestinal tract as well as diseases in remote sites such as the brain, lung, and eye. As such, gut microbiome manipulation has been explored as a treatment for several diseases including, Clostridium difficile infection, inflammatory bowel disease (IBD), and rheumatic diseases. Microbiome manipulation techniques include dietary changes, pre and probiotics, and fecal microbiota transplantation (FMT). Some dietary changes in IBD, including gluten-free and vegetarian diets, were shown to change the gut microbiome (e.g., genera Bacteroides, Faecalibacterium, Blautia) but had a limited effect on clinical outcomes (e.g., surgical complication, fistula formation, hospitalization). While other diets, such as low fermentable oligosaccharides, disaccharides, monosaccharides, and polyols (FODMAP) diet and high adherence to a Mediterranean diet, were shown to improve IBD and rheumatoid arthritis disease activity (e.g., stool frequency, joint tenderness), as well as change the gut microbiome (e.g., F. pransnitzii spp, Blautia). Pre and probiotic therapies have had more promising results, especially in IBD, with significant improvements in disease activity, intestinal permeability, and endoscopic findings following the intervention. Lastly, while FMT has been most frequently studied as a treatment for C. difficile infection, it has also been applied to immune diseases (e.g., ulcerative colitis, graft vs. host disease (GVHD), immune-mediated dry eye), with the goal of transplanting beneficial bacteria (e.g., Blautia, Faecalibacterium, and Bacteroides) from a healthy donor. Finally, probiotics have also been delivered to locations outside the gut, with Lactobacillus eye drops investigated for vernal keratoconjunctivitis. This chapter discusses how microbiome manipulations (gut and eye) have been used to modulate clinical outcomes of diseases that have relevance to the eye (e.g., autoimmune diseases) and discusses how these strategies may be applied in the future to the treatment of eye diseases in which microbiome abnormalities have been implicated (e.g., uveitis, dry eye, diabetic retinopathy)." @default.
• W4381954767 created "2023-06-26" @default.
• W4381954767 creator A5001072018 @default.
• W4381954767 creator A5081658152 @default.
• W4381954767 creator A5084526186 @default.
• W4381954767 date "2023-01-01" @default.
• W4381954767 modified "2023-09-23" @default.
• W4381954767 title "Microbiome manipulation as a target for eye diseases: lessons from humans" @default.
• W4381954767 cites W1420654867 @default.
• W4381954767 cites W1970464037 @default.
• W4381954767 cites W1978258044 @default.
• W4381954767 cites W1985760911 @default.
• W4381954767 cites W2004506978 @default.
• W4381954767 cites W2021079591 @default.
• W4381954767 cites W2023907260 @default.
• W4381954767 cites W2046683265 @default.
• W4381954767 cites W2047703946 @default.
• W4381954767 cites W2048502267 @default.
• W4381954767 cites W2048830729 @default.
• W4381954767 cites W2050341344 @default.
• W4381954767 cites W2070182507 @default.
• W4381954767 cites W2078754045 @default.
• W4381954767 cites W2079952394 @default.
• W4381954767 cites W2082186846 @default.
• W4381954767 cites W2088192427 @default.
• W4381954767 cites W2096160104 @default.
• W4381954767 cites W2105288471 @default.
• W4381954767 cites W2109569804 @default.
• W4381954767 cites W2113882071 @default.
• W4381954767 cites W2118173539 @default.
• W4381954767 cites W2125421792 @default.
• W4381954767 cites W2125826054 @default.
• W4381954767 cites W2132731835 @default.
• W4381954767 cites W2137795114 @default.
• W4381954767 cites W2145336165 @default.
• W4381954767 cites W2149952321 @default.
• W4381954767 cites W2156145269 @default.
• W4381954767 cites W2167837220 @default.
• W4381954767 cites W2193546234 @default.
• W4381954767 cites W2306621981 @default.
• W4381954767 cites W2324431491 @default.
• W4381954767 cites W2341975873 @default.
• W4381954767 cites W2402322497 @default.
• W4381954767 cites W2479125356 @default.
• W4381954767 cites W2512704070 @default.
• W4381954767 cites W2519959682 @default.
• W4381954767 cites W2521057774 @default.
• W4381954767 cites W2529584280 @default.
• W4381954767 cites W2588997555 @default.
• W4381954767 cites W2609340709 @default.
• W4381954767 cites W2736162768 @default.
• W4381954767 cites W2766078459 @default.
• W4381954767 cites W2769475001 @default.
• W4381954767 cites W2773707700 @default.
• W4381954767 cites W2778416039 @default.
• W4381954767 cites W2806271612 @default.
• W4381954767 cites W2809658684 @default.
• W4381954767 cites W2810558309 @default.
• W4381954767 cites W2882993821 @default.
• W4381954767 cites W2893006361 @default.
• W4381954767 cites W2902116186 @default.
• W4381954767 cites W2930879135 @default.
• W4381954767 cites W2934022621 @default.
• W4381954767 cites W2945625818 @default.
• W4381954767 cites W2946695204 @default.
• W4381954767 cites W2966917554 @default.
• W4381954767 cites W2978624250 @default.
• W4381954767 cites W3009017872 @default.
• W4381954767 cites W3022289262 @default.
• W4381954767 cites W3040547888 @default.
• W4381954767 cites W3112561388 @default.
• W4381954767 cites W3116655350 @default.
• W4381954767 cites W3131579497 @default.
• W4381954767 cites W3133755728 @default.
• W4381954767 cites W3134002069 @default.
• W4381954767 cites W3143113335 @default.
• W4381954767 cites W3177039901 @default.
• W4381954767 cites W3192943612 @default.
• W4381954767 cites W3209734272 @default.
• W4381954767 doi "https://doi.org/10.1016/b978-0-323-98338-9.00012-8" @default.
• W4381954767 hasPublicationYear "2023" @default.
• W4381954767 type Work @default.
• W4381954767 citedByCount "0" @default.
• W4381954767 crossrefType "book-chapter" @default.
• W4381954767 hasAuthorship W4381954767A5001072018 @default.
• W4381954767 hasAuthorship W4381954767A5081658152 @default.
• W4381954767 hasAuthorship W4381954767A5084526186 @default.
• W4381954767 hasConcept C126322002 @default.
• W4381954767 hasConcept C143121216 @default.
• W4381954767 hasConcept C203014093 @default.
• W4381954767 hasConcept C2777165150 @default.
• W4381954767 hasConcept C2778168646 @default.
• W4381954767 hasConcept C2778260677 @default.
• W4381954767 hasConcept C2779134260 @default.
• W4381954767 hasConcept C2780479503 @default.
• W4381954767 hasConcept C523546767 @default.
• W4381954767 hasConcept C539455810 @default.
• W4381954767 hasConcept C54355233 @default.

• next