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• W4381955113 abstract "This work deals with the issue of fluid simulation in type-B aortic dissections to support clinical treatment decision. We present the complete workflow to compute a fast closed-loop CFD model for patient-specific aortic-dissection management. Coupling of 0D and 3D approaches was investigated to assess the hemodynamics in aortic dissection. A novel approach to the definition of the boundary conditions at the fluid limits was proposed, based on a closed-loop 0D model of the full cardiovascular system and 3D static simulations. Patient-specific BCs were obtained using only non-invasive data from 2D PC MRI. An innovative approach based on ROMs was proposed to drastically reduce the computation time. ROMs were computed from 3D dynamic CFD-simulation results to evaluate the pressure at the wall, the WSS and the velocity fields. A good correspondence between the results of the ROMs and the simulations was achieved during the systolic phase. With the final model, 3D simulation results can be obtained in a few seconds for a setting of the 0D model of the full cardiovascular system. The proposed approach makes possible assessment of the outcome of treatment scenarios, such as the intake of beta-blockers to reduce the arterial pressure or hypertension. The results suggest good reliability for the proposed approach and can mimic the therapeutic effect of medical treatment." @default.
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• W4381955113 date "2023-01-01" @default.
• W4381955113 modified "2023-09-25" @default.
• W4381955113 title "Fast closed-loop CFD model for patient-specific aortic-dissection management" @default.
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• W4381955113 doi "https://doi.org/10.1016/b978-0-32-389967-3.00015-9" @default.
• W4381955113 hasPublicationYear "2023" @default.
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