Matches in SemOpenAlex for { <https://semopenalex.org/work/W4381988569> ?p ?o ?g. }
- W4381988569 endingPage "120234" @default.
- W4381988569 startingPage "120234" @default.
- W4381988569 abstract "The relationship between brain development and mechanical properties of brain tissue is important, but remains incompletely understood, in part due to the challenges in measuring these properties longitudinally over time. In addition, white matter, which is composed of aligned, myelinated, axonal fibers, may be mechanically anisotropic. Here we use data from magnetic resonance elastography (MRE) and diffusion tensor imaging (DTI) to estimate anisotropic mechanical properties in six female Yucatan minipigs at ages from 3 to 6 months. Fiber direction was estimated from the principal axis of the diffusion tensor in each voxel. Harmonic shear waves in the brain were excited by three different configurations of a jaw actuator and measured using a motion-sensitive MR imaging sequence. Anisotropic mechanical properties are estimated from displacement field and fiber direction data with a finite element- based, transversely-isotropic nonlinear inversion (TI-NLI) algorithm. TI-NLI finds spatially resolved TI material properties that minimize the error between measured and simulated displacement fields. Maps of anisotropic mechanical properties in the minipig brain were generated for each animal at all four ages. These maps show that white matter is more dissipative and anisotropic than gray matter, and reveal significant effects of brain development on brain stiffness and structural anisotropy. Changes in brain mechanical properties may be a fundamental biophysical signature of brain development." @default.
- W4381988569 created "2023-06-26" @default.
- W4381988569 creator A5022605229 @default.
- W4381988569 creator A5045394358 @default.
- W4381988569 creator A5062615331 @default.
- W4381988569 creator A5071474976 @default.
- W4381988569 creator A5080780024 @default.
- W4381988569 creator A5089799978 @default.
- W4381988569 date "2023-08-01" @default.
- W4381988569 modified "2023-10-15" @default.
- W4381988569 title "Mechanical stiffness and anisotropy measured by MRE during brain development in the minipig" @default.
- W4381988569 cites W1502435370 @default.
- W4381988569 cites W1512815393 @default.
- W4381988569 cites W1911907250 @default.
- W4381988569 cites W1963849487 @default.
- W4381988569 cites W1969583173 @default.
- W4381988569 cites W1970458214 @default.
- W4381988569 cites W1983588579 @default.
- W4381988569 cites W1988914162 @default.
- W4381988569 cites W2006096283 @default.
- W4381988569 cites W2008655880 @default.
- W4381988569 cites W2011155173 @default.
- W4381988569 cites W2017305439 @default.
- W4381988569 cites W2023412716 @default.
- W4381988569 cites W2025108982 @default.
- W4381988569 cites W2035928670 @default.
- W4381988569 cites W2036291324 @default.
- W4381988569 cites W2044559106 @default.
- W4381988569 cites W2052667073 @default.
- W4381988569 cites W2058734447 @default.
- W4381988569 cites W2074888367 @default.
- W4381988569 cites W2078950765 @default.
- W4381988569 cites W2083627232 @default.
- W4381988569 cites W2094423440 @default.
- W4381988569 cites W2095571280 @default.
- W4381988569 cites W2098489263 @default.
- W4381988569 cites W2112080359 @default.
- W4381988569 cites W2127890285 @default.
- W4381988569 cites W2136986949 @default.
- W4381988569 cites W2137924066 @default.
- W4381988569 cites W2139158372 @default.
- W4381988569 cites W2148571366 @default.
- W4381988569 cites W2157697096 @default.
- W4381988569 cites W2158738279 @default.
- W4381988569 cites W2161266571 @default.
- W4381988569 cites W2163636279 @default.
- W4381988569 cites W2172506796 @default.
- W4381988569 cites W2273083794 @default.
- W4381988569 cites W2288154064 @default.
- W4381988569 cites W2308001001 @default.
- W4381988569 cites W2334975795 @default.
- W4381988569 cites W2497468584 @default.
- W4381988569 cites W2519792225 @default.
- W4381988569 cites W2576420345 @default.
- W4381988569 cites W2589978863 @default.
- W4381988569 cites W2594705050 @default.
- W4381988569 cites W2747866083 @default.
- W4381988569 cites W2773894448 @default.
- W4381988569 cites W2774313104 @default.
- W4381988569 cites W2776496322 @default.
- W4381988569 cites W2788272865 @default.
- W4381988569 cites W2791517291 @default.
- W4381988569 cites W2793438451 @default.
- W4381988569 cites W2805667317 @default.
- W4381988569 cites W2895789855 @default.
- W4381988569 cites W2924246080 @default.
- W4381988569 cites W2969799474 @default.
- W4381988569 cites W2995936192 @default.
- W4381988569 cites W3002149960 @default.
- W4381988569 cites W3004069560 @default.
- W4381988569 cites W3024351050 @default.
- W4381988569 cites W3034161552 @default.
- W4381988569 cites W3116500811 @default.
- W4381988569 cites W3127045369 @default.
- W4381988569 cites W3133242395 @default.
- W4381988569 cites W3133902745 @default.
- W4381988569 cites W3139502049 @default.
- W4381988569 cites W3144765540 @default.
- W4381988569 cites W4200176193 @default.
- W4381988569 cites W4221132458 @default.
- W4381988569 cites W4281672318 @default.
- W4381988569 doi "https://doi.org/10.1016/j.neuroimage.2023.120234" @default.
- W4381988569 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37369255" @default.
- W4381988569 hasPublicationYear "2023" @default.
- W4381988569 type Work @default.
- W4381988569 citedByCount "1" @default.
- W4381988569 countsByYear W43819885692023 @default.
- W4381988569 crossrefType "journal-article" @default.
- W4381988569 hasAuthorship W4381988569A5022605229 @default.
- W4381988569 hasAuthorship W4381988569A5045394358 @default.
- W4381988569 hasAuthorship W4381988569A5062615331 @default.
- W4381988569 hasAuthorship W4381988569A5071474976 @default.
- W4381988569 hasAuthorship W4381988569A5080780024 @default.
- W4381988569 hasAuthorship W4381988569A5089799978 @default.
- W4381988569 hasBestOaLocation W43819885691 @default.
- W4381988569 hasConcept C101842124 @default.
- W4381988569 hasConcept C107551265 @default.
- W4381988569 hasConcept C120665830 @default.