FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4382010987> ?p ?o ?g. }

• W4382010987 endingPage "306" @default.
• W4382010987 startingPage "298" @default.
• W4382010987 abstract "This cross-sectional pilot study explored extracellular vesicle (EV)-derived gene expression of markers for bone turnover and pro-inflammatory cytokines in periodontal disease. Whole unstimulated saliva was collected from 52 participants (18 healthy, 13 gingivitis, and 21 stages III/IV periodontitis), from which salivary small extracellular vesicles (sEVs) were enriched using the size-exclusion chromatography method, and characterized by morphology, EV-protein, and size distribution, using transmission electron microscopy (TEM), enzyme-linked immunosorbent assay (ELISA), and Nanoparticle Tracking Analysis (NTA), respectively. Bone turnover markers and pro-inflammatory cytokines in salivary sEVs were evaluated using reverse transcription PCR. Salivary sEVs morphology, mode, size distribution, and particle concentration were comparable between healthy, gingivitis, and periodontitis patients. The CD9+ subpopulation was significantly higher in periodontitis-derived salivary sEVs compared with healthy. The detection of sEVs mRNA for osterix and tumor necrosis factor-alpha was significantly decreased and increased, respectively, in periodontitis compared with healthy controls, with good discriminatory power for periodontitis diagnosis (area under the curve >0.72). This pilot study demonstrated that salivary sEVs mRNAs may serve as a potential noninvasive biomarker source for periodontitis diagnosis. This pilot study investigated the potential of using salivary small extracellular vesicles (sEVs) derived from saliva as a noninvasive biomarker source for periodontal disease diagnosis. Whole unstimulated saliva was collected from healthy individuals, gingivitis, and stages III/IV periodontitis. The results showed that sEVs mRNA for the bone turnover marker osterix and the pro-inflammatory cytokine marker tumor necrosis factor-alpha had good discriminatory power for periodontitis diagnosis. This research highlights the potential of sEVs as a diagnostic tool for periodontal disease." @default.
• W4382010987 created "2023-06-27" @default.
• W4382010987 creator A5023900545 @default.
• W4382010987 creator A5034900987 @default.
• W4382010987 creator A5039634269 @default.
• W4382010987 creator A5043762120 @default.
• W4382010987 creator A5069080804 @default.
• W4382010987 creator A5089194971 @default.
• W4382010987 creator A5090491662 @default.
• W4382010987 date "2023-07-01" @default.
• W4382010987 modified "2023-09-23" @default.
• W4382010987 title "<i>TNF-α and OSX</i> mRNA of Salivary Small Extracellular Vesicles in Periodontitis: A Pilot Study" @default.
• W4382010987 cites W1747197150 @default.
• W4382010987 cites W1995026429 @default.
• W4382010987 cites W2001345959 @default.
• W4382010987 cites W2036932056 @default.
• W4382010987 cites W2043211210 @default.
• W4382010987 cites W2157348113 @default.
• W4382010987 cites W2193576967 @default.
• W4382010987 cites W2259481044 @default.
• W4382010987 cites W2786514708 @default.
• W4382010987 cites W2892294576 @default.
• W4382010987 cites W2900756811 @default.
• W4382010987 cites W2903652787 @default.
• W4382010987 cites W2918313915 @default.
• W4382010987 cites W2922078789 @default.
• W4382010987 cites W2929246859 @default.
• W4382010987 cites W2976290990 @default.
• W4382010987 cites W2981007428 @default.
• W4382010987 cites W3000084388 @default.
• W4382010987 cites W3013264957 @default.
• W4382010987 cites W3013273931 @default.
• W4382010987 cites W3016415602 @default.
• W4382010987 cites W3023972696 @default.
• W4382010987 cites W3044928444 @default.
• W4382010987 cites W3044936974 @default.
• W4382010987 cites W3108367345 @default.
• W4382010987 cites W3133758098 @default.
• W4382010987 cites W3203490587 @default.
• W4382010987 cites W3214253007 @default.
• W4382010987 cites W3217389577 @default.
• W4382010987 cites W4206038195 @default.
• W4382010987 cites W4214933741 @default.
• W4382010987 cites W4220948905 @default.
• W4382010987 cites W4221056746 @default.
• W4382010987 cites W4230233764 @default.
• W4382010987 cites W4250836980 @default.
• W4382010987 cites W4283075359 @default.
• W4382010987 cites W4283212553 @default.
• W4382010987 cites W4283743145 @default.
• W4382010987 cites W4302759939 @default.
• W4382010987 cites W4306149767 @default.
• W4382010987 cites W4307425006 @default.
• W4382010987 cites W4308058744 @default.
• W4382010987 cites W4309835417 @default.
• W4382010987 cites W4318570099 @default.
• W4382010987 doi "https://doi.org/10.1089/ten.tec.2023.0051" @default.
• W4382010987 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37358387" @default.
• W4382010987 hasPublicationYear "2023" @default.
• W4382010987 type Work @default.
• W4382010987 citedByCount "0" @default.
• W4382010987 crossrefType "journal-article" @default.
• W4382010987 hasAuthorship W4382010987A5023900545 @default.
• W4382010987 hasAuthorship W4382010987A5034900987 @default.
• W4382010987 hasAuthorship W4382010987A5039634269 @default.
• W4382010987 hasAuthorship W4382010987A5043762120 @default.
• W4382010987 hasAuthorship W4382010987A5069080804 @default.
• W4382010987 hasAuthorship W4382010987A5089194971 @default.
• W4382010987 hasAuthorship W4382010987A5090491662 @default.
• W4382010987 hasConcept C104317684 @default.
• W4382010987 hasConcept C126322002 @default.
• W4382010987 hasConcept C145059251 @default.
• W4382010987 hasConcept C17991360 @default.
• W4382010987 hasConcept C185592680 @default.
• W4382010987 hasConcept C199343813 @default.
• W4382010987 hasConcept C203014093 @default.
• W4382010987 hasConcept C20518536 @default.
• W4382010987 hasConcept C2778690821 @default.
• W4382010987 hasConcept C2779337755 @default.
• W4382010987 hasConcept C2780385504 @default.
• W4382010987 hasConcept C2780791200 @default.
• W4382010987 hasConcept C2781197716 @default.
• W4382010987 hasConcept C28406088 @default.
• W4382010987 hasConcept C2908689518 @default.
• W4382010987 hasConcept C504460877 @default.
• W4382010987 hasConcept C55493867 @default.
• W4382010987 hasConcept C71924100 @default.
• W4382010987 hasConcept C86803240 @default.
• W4382010987 hasConcept C95444343 @default.
• W4382010987 hasConceptScore W4382010987C104317684 @default.
• W4382010987 hasConceptScore W4382010987C126322002 @default.
• W4382010987 hasConceptScore W4382010987C145059251 @default.
• W4382010987 hasConceptScore W4382010987C17991360 @default.
• W4382010987 hasConceptScore W4382010987C185592680 @default.
• W4382010987 hasConceptScore W4382010987C199343813 @default.
• W4382010987 hasConceptScore W4382010987C203014093 @default.
• W4382010987 hasConceptScore W4382010987C20518536 @default.
• W4382010987 hasConceptScore W4382010987C2778690821 @default.

• next