FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4382011176> ?p ?o ?g. }

• W4382011176 endingPage "959" @default.
• W4382011176 startingPage "953" @default.
• W4382011176 abstract "Summary We explored the relevance of genomic microarrays (GM) in the refinement of prognosis in newly diagnosed low‐risk chronic lymphocytic leukaemia (CLL) patients as defined by isolated del(13q) or no lesions by a standard 4 probe fluorescence in situ hybridization (FISH) analysis. Compared to FISH, additional lesions were detected by GM in 27 of the 119 patients (22.7%). The concordance rate between FISH and GM was 87.4%. Discordant results between cytogenetic banding analysis (CBA) and GM were observed in 45/119 cases (37.8%) and were mainly due to the intrinsic characteristics of each technique. The presence of additional lesions by GM was associated with age > 65 years ( p = 0.047), advanced Binet stage ( p = 0.001), CLL‐IPI score ( p < 0.001), a complex karyotype ( p = 0.004) and a worse time‐to‐first treatment in multivariate analysis ( p = 0.009). Additional lesions by GM were also significantly associated with a worse time‐to‐first treatment in the subset of patients with wild‐type TP53 and mutated IGHV ( p = 0.025). In CLL patients with low‐risk features, the presence of additional lesions identified by GM helps to identify a subset of patients with a worse outcome that could be proposed for a risk‐adapted follow‐up and for early treatment including targeted agents within clinical trials." @default.
• W4382011176 created "2023-06-27" @default.
• W4382011176 creator A5009431453 @default.
• W4382011176 creator A5014776132 @default.
• W4382011176 creator A5017357493 @default.
• W4382011176 creator A5023512121 @default.
• W4382011176 creator A5024308788 @default.
• W4382011176 creator A5025297266 @default.
• W4382011176 creator A5034415866 @default.
• W4382011176 creator A5047961182 @default.
• W4382011176 creator A5050297033 @default.
• W4382011176 creator A5062047451 @default.
• W4382011176 creator A5064634047 @default.
• W4382011176 creator A5067326495 @default.
• W4382011176 creator A5069068528 @default.
• W4382011176 creator A5086706420 @default.
• W4382011176 date "2023-06-26" @default.
• W4382011176 modified "2023-10-14" @default.
• W4382011176 title "Additional lesions identified by genomic microarrays are associated with an inferior outcome in low‐risk chronic lymphocytic leukaemia patients" @default.
• W4382011176 cites W1968246063 @default.
• W4382011176 cites W2055898543 @default.
• W4382011176 cites W2091168608 @default.
• W4382011176 cites W2124193149 @default.
• W4382011176 cites W2139291723 @default.
• W4382011176 cites W2166657289 @default.
• W4382011176 cites W2290905118 @default.
• W4382011176 cites W2317888977 @default.
• W4382011176 cites W2518822109 @default.
• W4382011176 cites W2607604861 @default.
• W4382011176 cites W2747399191 @default.
• W4382011176 cites W2754916611 @default.
• W4382011176 cites W2790385276 @default.
• W4382011176 cites W2896048754 @default.
• W4382011176 cites W2907155822 @default.
• W4382011176 cites W3002788758 @default.
• W4382011176 cites W3014127006 @default.
• W4382011176 cites W3015305377 @default.
• W4382011176 cites W3116204576 @default.
• W4382011176 cites W3134161841 @default.
• W4382011176 cites W3155803123 @default.
• W4382011176 cites W3183349190 @default.
• W4382011176 cites W3203683811 @default.
• W4382011176 cites W3204168645 @default.
• W4382011176 cites W3214546710 @default.
• W4382011176 cites W4235474157 @default.
• W4382011176 cites W4281385697 @default.
• W4382011176 cites W4312140342 @default.
• W4382011176 cites W62561355 @default.
• W4382011176 doi "https://doi.org/10.1111/bjh.18946" @default.
• W4382011176 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37357817" @default.
• W4382011176 hasPublicationYear "2023" @default.
• W4382011176 type Work @default.
• W4382011176 citedByCount "1" @default.
• W4382011176 countsByYear W43820111762023 @default.
• W4382011176 crossrefType "journal-article" @default.
• W4382011176 hasAuthorship W4382011176A5009431453 @default.
• W4382011176 hasAuthorship W4382011176A5014776132 @default.
• W4382011176 hasAuthorship W4382011176A5017357493 @default.
• W4382011176 hasAuthorship W4382011176A5023512121 @default.
• W4382011176 hasAuthorship W4382011176A5024308788 @default.
• W4382011176 hasAuthorship W4382011176A5025297266 @default.
• W4382011176 hasAuthorship W4382011176A5034415866 @default.
• W4382011176 hasAuthorship W4382011176A5047961182 @default.
• W4382011176 hasAuthorship W4382011176A5050297033 @default.
• W4382011176 hasAuthorship W4382011176A5062047451 @default.
• W4382011176 hasAuthorship W4382011176A5064634047 @default.
• W4382011176 hasAuthorship W4382011176A5067326495 @default.
• W4382011176 hasAuthorship W4382011176A5069068528 @default.
• W4382011176 hasAuthorship W4382011176A5086706420 @default.
• W4382011176 hasBestOaLocation W43820111761 @default.
• W4382011176 hasConcept C104317684 @default.
• W4382011176 hasConcept C126322002 @default.
• W4382011176 hasConcept C142724271 @default.
• W4382011176 hasConcept C143998085 @default.
• W4382011176 hasConcept C146357865 @default.
• W4382011176 hasConcept C151730666 @default.
• W4382011176 hasConcept C160798450 @default.
• W4382011176 hasConcept C2777542201 @default.
• W4382011176 hasConcept C2777609679 @default.
• W4382011176 hasConcept C2777938653 @default.
• W4382011176 hasConcept C2778461978 @default.
• W4382011176 hasConcept C30481170 @default.
• W4382011176 hasConcept C38180746 @default.
• W4382011176 hasConcept C54355233 @default.
• W4382011176 hasConcept C63363279 @default.
• W4382011176 hasConcept C71924100 @default.
• W4382011176 hasConcept C86803240 @default.
• W4382011176 hasConcept C90924648 @default.
• W4382011176 hasConceptScore W4382011176C104317684 @default.
• W4382011176 hasConceptScore W4382011176C126322002 @default.
• W4382011176 hasConceptScore W4382011176C142724271 @default.
• W4382011176 hasConceptScore W4382011176C143998085 @default.
• W4382011176 hasConceptScore W4382011176C146357865 @default.
• W4382011176 hasConceptScore W4382011176C151730666 @default.
• W4382011176 hasConceptScore W4382011176C160798450 @default.
• W4382011176 hasConceptScore W4382011176C2777542201 @default.
• W4382011176 hasConceptScore W4382011176C2777609679 @default.
• W4382011176 hasConceptScore W4382011176C2777938653 @default.

• next