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• W4382020887 abstract "<ns4:p>A member of the RNA-binding protein family, T-cell intracellular antigen-1 (TIA1) regulates mRNA translation and splicing as well as cellular stress by promoting stress granule formation. Variants of the <ns4:italic>TIA1</ns4:italic> gene have implications in neurogenerative disorders including amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Reproducible research on TIA1 would be enhanced with the availability of high-quality anti-TIA1 antibodies. In this study, we characterized twelve TIA1 commercial antibodies for Western Blot, immunoprecipitation, and immunofluorescence using a standardized experimental protocol based on comparing read-outs in knockout cell lines and isogenic parental controls. We identified many high-performing antibodies and encourage readers to use this report as a guide to select the most appropriate antibody for their specific needs.</ns4:p>" @default.
• W4382020887 created "2023-06-27" @default.
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• W4382020887 date "2023-06-26" @default.
• W4382020887 modified "2023-09-27" @default.
• W4382020887 title "The identification of high-performing antibodies for RNA-binding protein TIA1 for use in Western Blot, immunoprecipitation and immunofluorescence" @default.
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• W4382020887 doi "https://doi.org/10.12688/f1000research.133645.1" @default.
• W4382020887 hasPublicationYear "2023" @default.
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