Matches in SemOpenAlex for { <https://semopenalex.org/work/W4382046861> ?p ?o ?g. }
Showing items 1 to 81 of
81
with 100 items per page.
- W4382046861 endingPage "727" @default.
- W4382046861 startingPage "720" @default.
- W4382046861 abstract "The win ratio was introduced into cardiovascular trials as a potentially better way of analyzing composite endpoints to account for the hierarchy of clinical significance of their components and to facilitate the inclusion of recurrent events. The basic concept of the win ratio is to define a hierarchy of clinical importance within the components of the composite outcome, form all possible pairs by comparing every subject in the treatment group with every subject in the control group, and then evaluate each pair for the occurrence of the components of the composite outcome in descending order of importance, starting at the most important and progressing down the hierarchy if the outcome does not result in a win in either pair until pairs are tied for the outcome after exhaustion of all components. Although the win ratio offers a novel method of depiction of outcomes in clinical trials, its advantages may be counterbalanced by several fallacies (such as ignoring ties and weighting each hierarchal component equally) and challenges in appropriate clinical interpretation (establishing clinical meaningfulness of the observed effect size). From this perspective, we discuss these and other fallacies and provide a suggested framework to overcome such limitations to enhance utility of this statistical method across the clinical trial enterprise." @default.
- W4382046861 created "2023-06-27" @default.
- W4382046861 creator A5051573897 @default.
- W4382046861 creator A5054679219 @default.
- W4382046861 creator A5058227921 @default.
- W4382046861 date "2023-06-01" @default.
- W4382046861 modified "2023-10-14" @default.
- W4382046861 title "Fallacies of Using the Win Ratio in Cardiovascular Trials" @default.
- W4382046861 cites W1870916828 @default.
- W4382046861 cites W2033980725 @default.
- W4382046861 cites W2105084079 @default.
- W4382046861 cites W2155440618 @default.
- W4382046861 cites W2888036721 @default.
- W4382046861 cites W2985596823 @default.
- W4382046861 cites W3027995531 @default.
- W4382046861 cites W3084342028 @default.
- W4382046861 cites W3152822781 @default.
- W4382046861 cites W3193653141 @default.
- W4382046861 cites W4292298343 @default.
- W4382046861 cites W4294958467 @default.
- W4382046861 cites W4323076139 @default.
- W4382046861 cites W4377148661 @default.
- W4382046861 cites W4377193384 @default.
- W4382046861 doi "https://doi.org/10.1016/j.jacbts.2023.05.004" @default.
- W4382046861 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37426527" @default.
- W4382046861 hasPublicationYear "2023" @default.
- W4382046861 type Work @default.
- W4382046861 citedByCount "0" @default.
- W4382046861 crossrefType "journal-article" @default.
- W4382046861 hasAuthorship W4382046861A5051573897 @default.
- W4382046861 hasAuthorship W4382046861A5054679219 @default.
- W4382046861 hasAuthorship W4382046861A5058227921 @default.
- W4382046861 hasBestOaLocation W43820468611 @default.
- W4382046861 hasConcept C126322002 @default.
- W4382046861 hasConcept C126838900 @default.
- W4382046861 hasConcept C144237770 @default.
- W4382046861 hasConcept C148220186 @default.
- W4382046861 hasConcept C15744967 @default.
- W4382046861 hasConcept C17744445 @default.
- W4382046861 hasConcept C183115368 @default.
- W4382046861 hasConcept C199539241 @default.
- W4382046861 hasConcept C31170391 @default.
- W4382046861 hasConcept C33923547 @default.
- W4382046861 hasConcept C41008148 @default.
- W4382046861 hasConcept C535046627 @default.
- W4382046861 hasConcept C71924100 @default.
- W4382046861 hasConceptScore W4382046861C126322002 @default.
- W4382046861 hasConceptScore W4382046861C126838900 @default.
- W4382046861 hasConceptScore W4382046861C144237770 @default.
- W4382046861 hasConceptScore W4382046861C148220186 @default.
- W4382046861 hasConceptScore W4382046861C15744967 @default.
- W4382046861 hasConceptScore W4382046861C17744445 @default.
- W4382046861 hasConceptScore W4382046861C183115368 @default.
- W4382046861 hasConceptScore W4382046861C199539241 @default.
- W4382046861 hasConceptScore W4382046861C31170391 @default.
- W4382046861 hasConceptScore W4382046861C33923547 @default.
- W4382046861 hasConceptScore W4382046861C41008148 @default.
- W4382046861 hasConceptScore W4382046861C535046627 @default.
- W4382046861 hasConceptScore W4382046861C71924100 @default.
- W4382046861 hasIssue "6" @default.
- W4382046861 hasLocation W43820468611 @default.
- W4382046861 hasLocation W43820468612 @default.
- W4382046861 hasLocation W43820468613 @default.
- W4382046861 hasOpenAccess W4382046861 @default.
- W4382046861 hasPrimaryLocation W43820468611 @default.
- W4382046861 hasRelatedWork W1994239590 @default.
- W4382046861 hasRelatedWork W2010492928 @default.
- W4382046861 hasRelatedWork W2046028226 @default.
- W4382046861 hasRelatedWork W2519422835 @default.
- W4382046861 hasRelatedWork W263354834 @default.
- W4382046861 hasRelatedWork W2748952813 @default.
- W4382046861 hasRelatedWork W2889237311 @default.
- W4382046861 hasRelatedWork W2899084033 @default.
- W4382046861 hasRelatedWork W2463097286 @default.
- W4382046861 hasRelatedWork W2466345496 @default.
- W4382046861 hasVolume "8" @default.
- W4382046861 isParatext "false" @default.
- W4382046861 isRetracted "false" @default.
- W4382046861 workType "article" @default.