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- W4382051520 abstract "Immune checkpoint inhibitors have revolutionized the management of many advanced cancers by producing robust remissions. They mostly target two immune regulatory pathways: cytotoxic T lymphocyte antigen-4 and programmed death-1 or its ligand. However, a flip side is the immune-related adverse events (irAEs) commonly affecting the gastrointestinal (GI) tract that can cause treatment interruptions or discontinuation. This practical review discusses the clinical and histopathologic findings of irAEs encountered in the luminal GI tract, along with histopathologic differentials that can mimic varied inflammatory, infectious, or other medication-associated etiologies and the importance of clinico-pathologic correlation for an accurate diagnosis." @default.
- W4382051520 created "2023-06-27" @default.
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- W4382051520 date "2023-06-01" @default.
- W4382051520 modified "2023-09-24" @default.
- W4382051520 title "Histopathologic Manifestations of Immune Checkpoint Inhibitor Therapy-Associated Gastrointestinal Tract Injury" @default.
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- W4382051520 doi "https://doi.org/10.1016/j.path.2023.05.007" @default.
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