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- W4382051896 endingPage "117160" @default.
- W4382051896 startingPage "117160" @default.
- W4382051896 abstract "Nucleic acids can be used as building blocks for highly regular and complex structures at the nanoscale due to their inherent self-assembly and programmability resulting from intra- and inter-molecular interactions. Three-way junctions (TWJs) structure is recognized as the smallest type of junction in nucleic acids. To form TWJ nanostructures, three DNA or RNA strands with complementary segments at each end are hybridized and form a Y-shaped structure. TWJ skeletons, having three independent arms, provide multifunctional sites for beneficial amplification, recognition, and signaling purposes in specific biomolecular nanoarchitecture. In this study, we represent the superiority aspects on the achievements of the biosensors with the cooperation of DNA/RNA TWJ nanoskeletons for monitoring different targets. Moreover, some discussions are declared to achieve a perspective for developing promising TWJ-based aptasensors in the future. This in-depth study can open a constructive way for commercializing and miniaturizing TWJ-tuned aptasensors as user-friendly lab-on-chip sensing devices." @default.
- W4382051896 created "2023-06-27" @default.
- W4382051896 creator A5000664644 @default.
- W4382051896 creator A5033097429 @default.
- W4382051896 creator A5038190626 @default.
- W4382051896 creator A5070602888 @default.
- W4382051896 creator A5072487912 @default.
- W4382051896 creator A5044972732 @default.
- W4382051896 date "2023-08-01" @default.
- W4382051896 modified "2023-10-02" @default.
- W4382051896 title "Three-way junction skeleton biosensors based on aptamers, DNAzymes, and DNA hybridization probes" @default.
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