FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4382137063> ?p ?o ?g. }

• W4382137063 abstract "Abstract Context Insulin resistance, glucose alterations, arterial hypertension (HTN), and the renin–angiotensin–aldosterone system (RAAS) are related in adult obesity. This crosstalk is still unexplored in childhood. Objective Characterize the relationships of fasting and postload glucose and insulin levels with new American Academy of Pediatrics classification of HTN and RAAS in pediatric obesity. Methods This was a retrospective observational study; 799 pediatric outpatients (11.4 ± 3.1 years) at a tertiary center who were overweight or obese and not yet on diet were included. The main outcome measures were mean and correlations among parameters of a complete clinical and metabolic screening (body mass index, blood pressure, and glucose and insulin levels during an oral glucose tolerance test, and renin and aldosterone levels and their ratio). Results 774 subjects had all the parameters, of whom 87.6% had HTN (5% elevated blood pressure, 29.2% stage I HTN, and 53.4% stage II HTN). Eighty subjects had 1 or more glucose alterations, and more frequently presented HTN. Blood pressure levels were higher in subjects with glucose alterations than in those with normal glucose levels. Fasting and stimulated glucose and insulin levels were directly related to the HTN stages, and insulin sensitivity was lower in HTN than in normal blood pressure. Aldosterone, renin, and aldosterone–renin ratio (ARR) were similar in sexes, whereas aldosterone was higher in prepubertal individuals. Subjects with impaired glucose tolerance (IGT) had higher renin and lower ARR. Renin was positively correlated with postload glucose, and ARR was negatively correlated with the Homeostatic Model Assessment for Insulin Resistance index. Conclusion A close relationship exists among insulin resistance, glucose alterations, HTN, and renin in childhood obesity. Specific categories of risk could provide indicators for strict clinical surveillance." @default.
• W4382137063 created "2023-06-27" @default.
• W4382137063 creator A5016162410 @default.
• W4382137063 creator A5017679162 @default.
• W4382137063 creator A5019524070 @default.
• W4382137063 creator A5022781111 @default.
• W4382137063 creator A5023714834 @default.
• W4382137063 creator A5066097075 @default.
• W4382137063 creator A5067938424 @default.
• W4382137063 creator A5068656783 @default.
• W4382137063 creator A5070977147 @default.
• W4382137063 creator A5073764611 @default.
• W4382137063 creator A5084026847 @default.
• W4382137063 creator A5088205924 @default.
• W4382137063 date "2023-06-26" @default.
• W4382137063 modified "2023-10-18" @default.
• W4382137063 title "Glucose Alterations, Insulin Resistance, Arterial Hypertension, and Renin are Strictly Associated in Pediatric Obesity" @default.
• W4382137063 cites W1695333005 @default.
• W4382137063 cites W1792110071 @default.
• W4382137063 cites W1933995831 @default.
• W4382137063 cites W1973450016 @default.
• W4382137063 cites W1973926831 @default.
• W4382137063 cites W2035821790 @default.
• W4382137063 cites W2039012179 @default.
• W4382137063 cites W2050107488 @default.
• W4382137063 cites W2057110351 @default.
• W4382137063 cites W2061309116 @default.
• W4382137063 cites W2080121039 @default.
• W4382137063 cites W2126327417 @default.
• W4382137063 cites W2152727838 @default.
• W4382137063 cites W2160234571 @default.
• W4382137063 cites W2290633895 @default.
• W4382137063 cites W2306940576 @default.
• W4382137063 cites W2334378791 @default.
• W4382137063 cites W2404914751 @default.
• W4382137063 cites W2499711396 @default.
• W4382137063 cites W2504372097 @default.
• W4382137063 cites W2528389922 @default.
• W4382137063 cites W2556707257 @default.
• W4382137063 cites W2607031541 @default.
• W4382137063 cites W2620406790 @default.
• W4382137063 cites W2625906169 @default.
• W4382137063 cites W2747721206 @default.
• W4382137063 cites W2762689525 @default.
• W4382137063 cites W2884483585 @default.
• W4382137063 cites W2910580108 @default.
• W4382137063 cites W2926160743 @default.
• W4382137063 cites W2946893712 @default.
• W4382137063 cites W2966771579 @default.
• W4382137063 cites W2991197074 @default.
• W4382137063 cites W2994308903 @default.
• W4382137063 cites W2996601650 @default.
• W4382137063 cites W3014094947 @default.
• W4382137063 cites W3023215525 @default.
• W4382137063 cites W3118251891 @default.
• W4382137063 cites W3121063299 @default.
• W4382137063 cites W3184722980 @default.
• W4382137063 cites W3192252346 @default.
• W4382137063 cites W3212156637 @default.
• W4382137063 cites W4210646795 @default.
• W4382137063 cites W4211003896 @default.
• W4382137063 cites W4223459680 @default.
• W4382137063 cites W4226076860 @default.
• W4382137063 cites W4235227254 @default.
• W4382137063 cites W4244971414 @default.
• W4382137063 cites W4283740731 @default.
• W4382137063 cites W4297005681 @default.
• W4382137063 cites W2766319287 @default.
• W4382137063 doi "https://doi.org/10.1210/jendso/bvad088" @default.
• W4382137063 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37424701" @default.
• W4382137063 hasPublicationYear "2023" @default.
• W4382137063 type Work @default.
• W4382137063 citedByCount "0" @default.
• W4382137063 crossrefType "journal-article" @default.
• W4382137063 hasAuthorship W4382137063A5016162410 @default.
• W4382137063 hasAuthorship W4382137063A5017679162 @default.
• W4382137063 hasAuthorship W4382137063A5019524070 @default.
• W4382137063 hasAuthorship W4382137063A5022781111 @default.
• W4382137063 hasAuthorship W4382137063A5023714834 @default.
• W4382137063 hasAuthorship W4382137063A5066097075 @default.
• W4382137063 hasAuthorship W4382137063A5067938424 @default.
• W4382137063 hasAuthorship W4382137063A5068656783 @default.
• W4382137063 hasAuthorship W4382137063A5070977147 @default.
• W4382137063 hasAuthorship W4382137063A5073764611 @default.
• W4382137063 hasAuthorship W4382137063A5084026847 @default.
• W4382137063 hasAuthorship W4382137063A5088205924 @default.
• W4382137063 hasBestOaLocation W43821370631 @default.
• W4382137063 hasConcept C126322002 @default.
• W4382137063 hasConcept C134018914 @default.
• W4382137063 hasConcept C138976137 @default.
• W4382137063 hasConcept C198710026 @default.
• W4382137063 hasConcept C2777391703 @default.
• W4382137063 hasConcept C2778525890 @default.
• W4382137063 hasConcept C2779306644 @default.
• W4382137063 hasConcept C2780221984 @default.
• W4382137063 hasConcept C2780586474 @default.
• W4382137063 hasConcept C2780609358 @default.
• W4382137063 hasConcept C3018667095 @default.
• W4382137063 hasConcept C511355011 @default.
• W4382137063 hasConcept C71924100 @default.

• next