FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4382137637> ?p ?o ?g. }

• W4382137637 endingPage "1648" @default.
• W4382137637 startingPage "1648" @default.
• W4382137637 abstract "Bifidobacterium longum is considered a microorganism with probiotic potential, which has been extensively studied, but these probiotic effects are strain dependent. This work aims to characterize the probiotic potential, based on the biochemical and genomic functionality, of B. longum LBUX23, isolated from neonates' feces. B. longum LBUX23 contains one circular genome of 2,287,838 bp with a G+C content of 60.05%, no plasmids, no CRISPR-Cas operon, possesses 56 tRNAs, 9 rRNAs, 1 tmRNA and 1776 coding sequences (CDSs). It has chromosomally encoded resistance genes to ampicillin and dicloxacillin, non-hemolytic activity, and moderate inhibition of Escherichia coli ATCC 25922 and to some emergent pathogen's clinical strains. B. longum LBUX23 was able to utilize lactose, sucrose, fructooligosaccharides (FOS), and lactulose. The maximum peak of bacterial growth was observed in sucrose and FOS at 6 h; in lactose and lactulose, it was shown at 8 h. B. longum LBUX23 can survive in gastrointestinal conditions (pH 4 to 7). A decrease in survival (96.5 and 93.8%) was observed at pH 3 and 3.5 during 120 min. argC, argH, and dapA genes could be involved in this tolerance. B. longum LBUX23 can also survive under primary and secondary glyco- or tauro-conjugated bile salts, and a mixture of bile salts due to the high extracellular bile salt hydrolase (BSH) activity (67.3 %), in taurocholic acid followed by taurodeoxycholic acid (48.5%), glycocholic acid (47.1%), oxgall (44.3%), and glycodeoxycholic acid (29.7%) probably due to the presence of the cbh and gnlE genes which form an operon (start: 119573 and end: 123812). Low BSH activity was determined intracellularly (<7%), particularly in glycocholic acid; no intracellular activity was shown. B. longum LBUX23 showed antioxidant effects in DPPH radical, mainly in intact cells (27.4%). In the case of hydroxyl radical scavenging capacity, cell debris showed the highest reduction (72.5%). In the cell-free extract, superoxide anion radical scavenging capacity was higher (90.5%). The genome of B. longum LBUX23 contains PNPOx, AhpC, Bcp, trxA, and trxB genes, which could be involved in this activity. Regarding adherence, it showed adherence up to 5% to Caco-2 cells. B. longum LBUX23 showed in vitro potential probiotic properties, mainly in BSH activity and antioxidant capacity, which indicates that it could be a good candidate for antioxidant or anti-cholesterol tests using in vivo models." @default.
• W4382137637 created "2023-06-27" @default.
• W4382137637 creator A5017486419 @default.
• W4382137637 creator A5018004295 @default.
• W4382137637 creator A5023850181 @default.
• W4382137637 creator A5026686919 @default.
• W4382137637 creator A5033830444 @default.
• W4382137637 creator A5051629962 @default.
• W4382137637 creator A5054290998 @default.
• W4382137637 creator A5056903629 @default.
• W4382137637 creator A5058014351 @default.
• W4382137637 creator A5063736959 @default.
• W4382137637 creator A5068678265 @default.
• W4382137637 creator A5092272103 @default.
• W4382137637 date "2023-06-24" @default.
• W4382137637 modified "2023-09-26" @default.
• W4382137637 title "Bifidobacterium longum LBUX23 Isolated from Feces of a Newborn; Potential Probiotic Properties and Genomic Characterization" @default.
• W4382137637 cites W165450341 @default.
• W4382137637 cites W1967450037 @default.
• W4382137637 cites W1970709775 @default.
• W4382137637 cites W1970857466 @default.
• W4382137637 cites W1974707233 @default.
• W4382137637 cites W1975671156 @default.
• W4382137637 cites W1991761975 @default.
• W4382137637 cites W1995056069 @default.
• W4382137637 cites W1998273216 @default.
• W4382137637 cites W2007006020 @default.
• W4382137637 cites W2015701509 @default.
• W4382137637 cites W2018390057 @default.
• W4382137637 cites W2018628066 @default.
• W4382137637 cites W2021896492 @default.
• W4382137637 cites W2029656557 @default.
• W4382137637 cites W2053287407 @default.
• W4382137637 cites W2055394486 @default.
• W4382137637 cites W2058447080 @default.
• W4382137637 cites W2072531137 @default.
• W4382137637 cites W2091273379 @default.
• W4382137637 cites W2096595394 @default.
• W4382137637 cites W2115487822 @default.
• W4382137637 cites W2132645356 @default.
• W4382137637 cites W2138171436 @default.
• W4382137637 cites W2142343447 @default.
• W4382137637 cites W2161587852 @default.
• W4382137637 cites W2164091046 @default.
• W4382137637 cites W2168640091 @default.
• W4382137637 cites W2200956820 @default.
• W4382137637 cites W2202001428 @default.
• W4382137637 cites W2416665208 @default.
• W4382137637 cites W2477632416 @default.
• W4382137637 cites W2521771323 @default.
• W4382137637 cites W2564755845 @default.
• W4382137637 cites W2610412885 @default.
• W4382137637 cites W2612206059 @default.
• W4382137637 cites W2613418115 @default.
• W4382137637 cites W2622475329 @default.
• W4382137637 cites W2627092521 @default.
• W4382137637 cites W2756417782 @default.
• W4382137637 cites W2782428046 @default.
• W4382137637 cites W2783183417 @default.
• W4382137637 cites W2799380720 @default.
• W4382137637 cites W2889309427 @default.
• W4382137637 cites W2900868342 @default.
• W4382137637 cites W2950237919 @default.
• W4382137637 cites W2989782331 @default.
• W4382137637 cites W2990826162 @default.
• W4382137637 cites W2992496759 @default.
• W4382137637 cites W3009449643 @default.
• W4382137637 cites W3025066265 @default.
• W4382137637 cites W3110377174 @default.
• W4382137637 cites W3127050546 @default.
• W4382137637 cites W3134750363 @default.
• W4382137637 cites W3137412740 @default.
• W4382137637 cites W3139493838 @default.
• W4382137637 cites W3158585279 @default.
• W4382137637 cites W3184597896 @default.
• W4382137637 cites W3184647012 @default.
• W4382137637 cites W3196941645 @default.
• W4382137637 cites W3201427358 @default.
• W4382137637 cites W3208076072 @default.
• W4382137637 cites W4200002208 @default.
• W4382137637 cites W4205822282 @default.
• W4382137637 cites W4213129183 @default.
• W4382137637 cites W4246769188 @default.
• W4382137637 cites W4253056992 @default.
• W4382137637 cites W4283079345 @default.
• W4382137637 cites W4296462642 @default.
• W4382137637 cites W4300427440 @default.
• W4382137637 cites W4307266387 @default.
• W4382137637 cites W4319826842 @default.
• W4382137637 doi "https://doi.org/10.3390/microorganisms11071648" @default.
• W4382137637 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37512821" @default.
• W4382137637 hasPublicationYear "2023" @default.
• W4382137637 type Work @default.
• W4382137637 citedByCount "0" @default.
• W4382137637 crossrefType "journal-article" @default.
• W4382137637 hasAuthorship W4382137637A5017486419 @default.
• W4382137637 hasAuthorship W4382137637A5018004295 @default.
• W4382137637 hasAuthorship W4382137637A5023850181 @default.

• next