Matches in SemOpenAlex for { <https://semopenalex.org/work/W4382361831> ?p ?o ?g. }
- W4382361831 abstract "Mesenchymal stem cell (MSC) therapies have been brought forward as a promising treatment modality for cutaneous wound healing. However, current approaches for stem cell delivery have many drawbacks, such as lack of targetability and cell loss, leading to poor efficacy of stem cell therapy. To overcome these problems, in the present study, an in situ cell electrospinning system is developed as an attractive approach for stem cell delivery. MSCs have a high cell viability of over 90% even with a high applied voltage of 15 kV post-cell electrospinning process. In addition, cell electrospinning does not show any negative effect on the surface marker expression and differentiation capacity of MSCs. In vivo studies demonstrate that in situ cell electrospinning treatment can promote cutaneous wound healing through direct deposition of bioactive fish gelatin fibers and MSCs onto wound sites, leading to a synergic therapeutic effect. The approach enhances extracellular matrix remodeling by increasing collagen deposition, promotes angiogenesis by increasing the expression of vascular endothelial growth factor (VEGF) and forming small blood vessels, and dramatically reduces the expression of interleukin-6 (IL-6) during wound healing. The use of in situ cell electrospinning system potentially provides a rapid, no touch, personalized treatment for cutaneous wound healing." @default.
- W4382361831 created "2023-06-29" @default.
- W4382361831 creator A5017578703 @default.
- W4382361831 creator A5019254820 @default.
- W4382361831 creator A5038291786 @default.
- W4382361831 creator A5043138062 @default.
- W4382361831 creator A5043839950 @default.
- W4382361831 creator A5051832489 @default.
- W4382361831 creator A5058423562 @default.
- W4382361831 creator A5059084134 @default.
- W4382361831 creator A5061140388 @default.
- W4382361831 creator A5068042852 @default.
- W4382361831 creator A5071660578 @default.
- W4382361831 creator A5085294805 @default.
- W4382361831 date "2023-07-09" @default.
- W4382361831 modified "2023-10-17" @default.
- W4382361831 title "In Situ Precision Cell Electrospinning as an Efficient Stem Cell Delivery Approach for Cutaneous Wound Healing" @default.
- W4382361831 cites W1608366086 @default.
- W4382361831 cites W1856884032 @default.
- W4382361831 cites W1987408673 @default.
- W4382361831 cites W1987544689 @default.
- W4382361831 cites W1998458266 @default.
- W4382361831 cites W2001179745 @default.
- W4382361831 cites W2006284739 @default.
- W4382361831 cites W2011859440 @default.
- W4382361831 cites W2029185806 @default.
- W4382361831 cites W2037618281 @default.
- W4382361831 cites W2067642526 @default.
- W4382361831 cites W2073136208 @default.
- W4382361831 cites W2097111636 @default.
- W4382361831 cites W2114805281 @default.
- W4382361831 cites W2153405392 @default.
- W4382361831 cites W2154729178 @default.
- W4382361831 cites W2167064041 @default.
- W4382361831 cites W2295058411 @default.
- W4382361831 cites W2566399670 @default.
- W4382361831 cites W2609526676 @default.
- W4382361831 cites W2761405265 @default.
- W4382361831 cites W2778936307 @default.
- W4382361831 cites W2792066971 @default.
- W4382361831 cites W2896646970 @default.
- W4382361831 cites W2906229978 @default.
- W4382361831 cites W2938764052 @default.
- W4382361831 cites W2943945769 @default.
- W4382361831 cites W2961955185 @default.
- W4382361831 cites W2963401751 @default.
- W4382361831 cites W2992980782 @default.
- W4382361831 cites W3004561447 @default.
- W4382361831 cites W3006743395 @default.
- W4382361831 cites W3047104964 @default.
- W4382361831 cites W3048040924 @default.
- W4382361831 cites W3049398895 @default.
- W4382361831 cites W3095894593 @default.
- W4382361831 cites W3182042652 @default.
- W4382361831 cites W3201300892 @default.
- W4382361831 cites W4211119500 @default.
- W4382361831 cites W4214523546 @default.
- W4382361831 cites W4247376412 @default.
- W4382361831 doi "https://doi.org/10.1002/adhm.202300970" @default.
- W4382361831 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37379527" @default.
- W4382361831 hasPublicationYear "2023" @default.
- W4382361831 type Work @default.
- W4382361831 citedByCount "0" @default.
- W4382361831 crossrefType "journal-article" @default.
- W4382361831 hasAuthorship W4382361831A5017578703 @default.
- W4382361831 hasAuthorship W4382361831A5019254820 @default.
- W4382361831 hasAuthorship W4382361831A5038291786 @default.
- W4382361831 hasAuthorship W4382361831A5043138062 @default.
- W4382361831 hasAuthorship W4382361831A5043839950 @default.
- W4382361831 hasAuthorship W4382361831A5051832489 @default.
- W4382361831 hasAuthorship W4382361831A5058423562 @default.
- W4382361831 hasAuthorship W4382361831A5059084134 @default.
- W4382361831 hasAuthorship W4382361831A5061140388 @default.
- W4382361831 hasAuthorship W4382361831A5068042852 @default.
- W4382361831 hasAuthorship W4382361831A5071660578 @default.
- W4382361831 hasAuthorship W4382361831A5085294805 @default.
- W4382361831 hasConcept C136229726 @default.
- W4382361831 hasConcept C137738243 @default.
- W4382361831 hasConcept C144796933 @default.
- W4382361831 hasConcept C1491633281 @default.
- W4382361831 hasConcept C159985019 @default.
- W4382361831 hasConcept C185592680 @default.
- W4382361831 hasConcept C189165786 @default.
- W4382361831 hasConcept C192562407 @default.
- W4382361831 hasConcept C198826908 @default.
- W4382361831 hasConcept C203014093 @default.
- W4382361831 hasConcept C2778823387 @default.
- W4382361831 hasConcept C2780269544 @default.
- W4382361831 hasConcept C2780394083 @default.
- W4382361831 hasConcept C28328180 @default.
- W4382361831 hasConcept C502942594 @default.
- W4382361831 hasConcept C521977710 @default.
- W4382361831 hasConcept C55493867 @default.
- W4382361831 hasConcept C71924100 @default.
- W4382361831 hasConcept C86803240 @default.
- W4382361831 hasConcept C95444343 @default.
- W4382361831 hasConceptScore W4382361831C136229726 @default.
- W4382361831 hasConceptScore W4382361831C137738243 @default.
- W4382361831 hasConceptScore W4382361831C144796933 @default.
- W4382361831 hasConceptScore W4382361831C1491633281 @default.