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• W4382393882 abstract "A rapid and simple method was developed for sildenafil citrate (SILC) drug (the active component of Viagra) determination by electrochemical analysis using a screen-printed glassy carbon electrode (SPGCE). Initial investigations were undertaken using cyclic voltammetry (CV) to characterize the redox behavior at the SPCE. The respective current response has been evaluated with respect to the drug composition, pH of the supporting electrolyte, potential and scan rate. In addition, square wave voltammetry (SWV) was carried out to ascertain whether trace amount of samples could be detected. From these studies it was shown that the electrode exhibited linear response in the concentration range from 1.0×10-6 to 1.4×10-5 molL-1 with good reproducibility. The limit of detection was found to be 5.5×10-8 molL-1. An interference study was also carried in presence of high concentration of ascorbic acid (AA) and uric acid (UA) to estimate the high selectivity of the electrode. The method was successfully applied for the determination of SILC in spiked human urine and pharmaceutical samples with good agreement between the added and recovery values." @default.
• W4382393882 created "2023-06-29" @default.
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• W4382393882 date "2012-12-01" @default.
• W4382393882 modified "2023-10-17" @default.
• W4382393882 title "A Novel Electrochemical Sensor for Determination of Sildenafil Citrate (Viagra) in Pure Form and in Biological and Pharmaceutical Formulations" @default.
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• W4382393882 doi "https://doi.org/10.1016/s1452-3981(23)16605-3" @default.
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