FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4382450748> ?p ?o ?g. }

• W4382450748 abstract "Objective Atherosclerosis expression varies across not only coronary, cerebrovascular, and peripheral arteries but also within the peripheral vascular tree. The underlying pathomechanisms of distinct atherosclerosis phenotypes in lower extremity peripheral artery disease (PAD) is poorly understood. We investigated the association of cardiovascular risk factors (CVRFs) and atherosclerosis distribution in a targeted approach analyzing symptomatic patients with isolated anatomic phenotypes of PAD. Methods In a cross-sectional analysis of consecutive patients undergoing first-time endovascular recanalization for symptomatic PAD, data of patients with isolated anatomic phenotypes of either proximal (iliac) or distal (infrageniculate) atherosclerosis segregation were extracted. We performed a multivariable logistic regression model with backward elimination to investigate the association of proximal and distal PAD with CVRFs. Results Of the 637 patients (29% females) with endovascular recanalization, 351 (55%) had proximal and 286 (45%) had distal atherosclerosis. Female sex [odds ratio (OR) 0.33, 95% confidence interval (CI) 0.20–0.54, p = 0.01], active smoking (OR 0.16, 95% CI 0.09–0.28, p &lt; 0.001), and former smoking (OR 0.33, 95% CI 0.20–0.57, p &lt; 0.001) were associated with proximal disease. Diabetes mellitus (DM) (OR 3.25, 95% CI 1.93–5.46, p &lt; 0.001), chronic kidney disease (CKD) (OR 1.18, 95% CI 1.08–1.28, p &lt; 0.001), and older age (OR 1.31, 95% CI 1.06–1.61, p = 0.01) were associated with distal disease. Conclusion Female sex, particularly in the context of smoking, is associated with clinically relevant, proximal atherosclerosis expression. Our additional findings that distal atherosclerosis expression is associated with DM, CKD, and older age suggest that PAD has at least two distinct atherosclerotic phenotypes with sex-specific and individual susceptibility to atherogenic risk factors." @default.
• W4382450748 created "2023-06-29" @default.
• W4382450748 creator A5000948299 @default.
• W4382450748 creator A5006978988 @default.
• W4382450748 creator A5010881813 @default.
• W4382450748 creator A5020778273 @default.
• W4382450748 creator A5063726355 @default.
• W4382450748 creator A5073621568 @default.
• W4382450748 creator A5078388306 @default.
• W4382450748 creator A5084489827 @default.
• W4382450748 date "2023-06-27" @default.
• W4382450748 modified "2023-10-18" @default.
• W4382450748 title "Association of sex and cardiovascular risk factors with atherosclerosis distribution pattern in lower extremity peripheral artery disease" @default.
• W4382450748 cites W1607804102 @default.
• W4382450748 cites W1955505634 @default.
• W4382450748 cites W1972116991 @default.
• W4382450748 cites W1972451748 @default.
• W4382450748 cites W2001465635 @default.
• W4382450748 cites W2012905414 @default.
• W4382450748 cites W2019071303 @default.
• W4382450748 cites W2022995515 @default.
• W4382450748 cites W2025748898 @default.
• W4382450748 cites W2037500444 @default.
• W4382450748 cites W2040816046 @default.
• W4382450748 cites W2041744791 @default.
• W4382450748 cites W2044658006 @default.
• W4382450748 cites W2064657550 @default.
• W4382450748 cites W2068886931 @default.
• W4382450748 cites W2073434079 @default.
• W4382450748 cites W2084238683 @default.
• W4382450748 cites W2091489877 @default.
• W4382450748 cites W2102505453 @default.
• W4382450748 cites W2110101054 @default.
• W4382450748 cites W2116829637 @default.
• W4382450748 cites W2129750583 @default.
• W4382450748 cites W2135989027 @default.
• W4382450748 cites W2142164422 @default.
• W4382450748 cites W2143079282 @default.
• W4382450748 cites W2144451747 @default.
• W4382450748 cites W2148374679 @default.
• W4382450748 cites W2152877944 @default.
• W4382450748 cites W2166964425 @default.
• W4382450748 cites W2169428949 @default.
• W4382450748 cites W2275204317 @default.
• W4382450748 cites W2280573257 @default.
• W4382450748 cites W2330129429 @default.
• W4382450748 cites W2338355768 @default.
• W4382450748 cites W2556414715 @default.
• W4382450748 cites W2556838984 @default.
• W4382450748 cites W2606382560 @default.
• W4382450748 cites W2748400555 @default.
• W4382450748 cites W2767660506 @default.
• W4382450748 cites W2783626122 @default.
• W4382450748 cites W2793268332 @default.
• W4382450748 cites W2959924472 @default.
• W4382450748 cites W2975859535 @default.
• W4382450748 cites W3011371150 @default.
• W4382450748 cites W3013428853 @default.
• W4382450748 cites W4229536675 @default.
• W4382450748 cites W4239715795 @default.
• W4382450748 cites W4241151929 @default.
• W4382450748 doi "https://doi.org/10.3389/fcvm.2023.1004003" @default.
• W4382450748 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37441701" @default.
• W4382450748 hasPublicationYear "2023" @default.
• W4382450748 type Work @default.
• W4382450748 citedByCount "0" @default.
• W4382450748 crossrefType "journal-article" @default.
• W4382450748 hasAuthorship W4382450748A5000948299 @default.
• W4382450748 hasAuthorship W4382450748A5006978988 @default.
• W4382450748 hasAuthorship W4382450748A5010881813 @default.
• W4382450748 hasAuthorship W4382450748A5020778273 @default.
• W4382450748 hasAuthorship W4382450748A5063726355 @default.
• W4382450748 hasAuthorship W4382450748A5073621568 @default.
• W4382450748 hasAuthorship W4382450748A5078388306 @default.
• W4382450748 hasAuthorship W4382450748A5084489827 @default.
• W4382450748 hasBestOaLocation W43824507481 @default.
• W4382450748 hasConcept C126322002 @default.
• W4382450748 hasConcept C134018914 @default.
• W4382450748 hasConcept C151730666 @default.
• W4382450748 hasConcept C156957248 @default.
• W4382450748 hasConcept C164705383 @default.
• W4382450748 hasConcept C2777466421 @default.
• W4382450748 hasConcept C2778213512 @default.
• W4382450748 hasConcept C2778653478 @default.
• W4382450748 hasConcept C2779134260 @default.
• W4382450748 hasConcept C2779343474 @default.
• W4382450748 hasConcept C44249647 @default.
• W4382450748 hasConcept C46762472 @default.
• W4382450748 hasConcept C50440223 @default.
• W4382450748 hasConcept C555293320 @default.
• W4382450748 hasConcept C71924100 @default.
• W4382450748 hasConcept C86803240 @default.
• W4382450748 hasConceptScore W4382450748C126322002 @default.
• W4382450748 hasConceptScore W4382450748C134018914 @default.
• W4382450748 hasConceptScore W4382450748C151730666 @default.
• W4382450748 hasConceptScore W4382450748C156957248 @default.
• W4382450748 hasConceptScore W4382450748C164705383 @default.
• W4382450748 hasConceptScore W4382450748C2777466421 @default.
• W4382450748 hasConceptScore W4382450748C2778213512 @default.
• W4382450748 hasConceptScore W4382450748C2778653478 @default.

• next