FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4382560818> ?p ?o ?g. }

• W4382560818 endingPage "4339" @default.
• W4382560818 startingPage "4339" @default.
• W4382560818 abstract "The aim of this research was to investigate potential new biomarkers which could be used in the clinical practice of ulcerative colitis (UC). Given the crucial role of intestinal barrier integrity and inflammation in the pathogenesis of UC, the serum profile of proteins linked to intestinal barrier and pro-inflammatory neutrophil products may be useful in diagnosing and monitoring the activity of the disease. We measured serum levels of proguanylin (pro-GN), S100A12, and pentraxin 3 (PTX3) in 31 patients with UC before and after a year of biological treatment, as well as in 20 healthy individuals. Significant differences in the serum profiles of pro-GN (5.27 vs. 11.35, p < 0.001), S100A12 (39.36 vs. 19.74, p < 0.001) and PTX3 (3197.05 vs. 1608.37, p < 0.001) were observed between pre-treatment patients with UC and healthy individuals. Furthermore, in UC patients prior to treatment, the levels of S100A12 (p < 0.0005; r = 0.628) and PTX3 (p < 0.05; r = 0.371) were correlated with disease activity as measured by the Mayo scale. Following a year of biological treatment with adalimumab, the concentration of pro-GN significantly increased (5.27 vs. 6.68, p < 0.005) in the blood of UC patients, while the level of PTX-3 decreased (3197.05 vs. 1946.4, p < 0.0001). Our study demonstrates the usefulness of pro-GN, S100A12, and PTX3 measurements in diagnosing and monitoring the activity of UC." @default.
• W4382560818 created "2023-06-30" @default.
• W4382560818 creator A5019943456 @default.
• W4382560818 creator A5034896892 @default.
• W4382560818 creator A5041670607 @default.
• W4382560818 creator A5061931057 @default.
• W4382560818 creator A5090285280 @default.
• W4382560818 creator A5092359789 @default.
• W4382560818 date "2023-06-28" @default.
• W4382560818 modified "2023-10-05" @default.
• W4382560818 title "Circulating Profiles of Serum Proguanylin, S100A12 Protein and Pentraxin 3 as Diagnostic Markers of Ulcerative Colitis" @default.
• W4382560818 cites W1678264379 @default.
• W4382560818 cites W1906225032 @default.
• W4382560818 cites W1938587120 @default.
• W4382560818 cites W1968062436 @default.
• W4382560818 cites W1974217486 @default.
• W4382560818 cites W1985071935 @default.
• W4382560818 cites W2016219300 @default.
• W4382560818 cites W2030502069 @default.
• W4382560818 cites W2046721013 @default.
• W4382560818 cites W2050093406 @default.
• W4382560818 cites W2072880806 @default.
• W4382560818 cites W2082732215 @default.
• W4382560818 cites W2109334664 @default.
• W4382560818 cites W2116117589 @default.
• W4382560818 cites W2152676422 @default.
• W4382560818 cites W2161888715 @default.
• W4382560818 cites W2168401684 @default.
• W4382560818 cites W2258570989 @default.
• W4382560818 cites W2344106843 @default.
• W4382560818 cites W2564504700 @default.
• W4382560818 cites W2582591980 @default.
• W4382560818 cites W2599036809 @default.
• W4382560818 cites W2775212432 @default.
• W4382560818 cites W2913284233 @default.
• W4382560818 cites W2926015082 @default.
• W4382560818 cites W2938319506 @default.
• W4382560818 cites W3017785560 @default.
• W4382560818 cites W3020407014 @default.
• W4382560818 cites W3034732603 @default.
• W4382560818 cites W3059160719 @default.
• W4382560818 cites W3083820091 @default.
• W4382560818 cites W4297201396 @default.
• W4382560818 doi "https://doi.org/10.3390/jcm12134339" @default.
• W4382560818 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37445374" @default.
• W4382560818 hasPublicationYear "2023" @default.
• W4382560818 type Work @default.
• W4382560818 citedByCount "1" @default.
• W4382560818 countsByYear W43825608182023 @default.
• W4382560818 crossrefType "journal-article" @default.
• W4382560818 hasAuthorship W4382560818A5019943456 @default.
• W4382560818 hasAuthorship W4382560818A5034896892 @default.
• W4382560818 hasAuthorship W4382560818A5041670607 @default.
• W4382560818 hasAuthorship W4382560818A5061931057 @default.
• W4382560818 hasAuthorship W4382560818A5090285280 @default.
• W4382560818 hasAuthorship W4382560818A5092359789 @default.
• W4382560818 hasBestOaLocation W43825608181 @default.
• W4382560818 hasConcept C126322002 @default.
• W4382560818 hasConcept C127901578 @default.
• W4382560818 hasConcept C185592680 @default.
• W4382560818 hasConcept C203014093 @default.
• W4382560818 hasConcept C2776914184 @default.
• W4382560818 hasConcept C2779134260 @default.
• W4382560818 hasConcept C2780132546 @default.
• W4382560818 hasConcept C2780479503 @default.
• W4382560818 hasConcept C2780942790 @default.
• W4382560818 hasConcept C2781195455 @default.
• W4382560818 hasConcept C2781197716 @default.
• W4382560818 hasConcept C55493867 @default.
• W4382560818 hasConcept C71924100 @default.
• W4382560818 hasConcept C90924648 @default.
• W4382560818 hasConceptScore W4382560818C126322002 @default.
• W4382560818 hasConceptScore W4382560818C127901578 @default.
• W4382560818 hasConceptScore W4382560818C185592680 @default.
• W4382560818 hasConceptScore W4382560818C203014093 @default.
• W4382560818 hasConceptScore W4382560818C2776914184 @default.
• W4382560818 hasConceptScore W4382560818C2779134260 @default.
• W4382560818 hasConceptScore W4382560818C2780132546 @default.
• W4382560818 hasConceptScore W4382560818C2780479503 @default.
• W4382560818 hasConceptScore W4382560818C2780942790 @default.
• W4382560818 hasConceptScore W4382560818C2781195455 @default.
• W4382560818 hasConceptScore W4382560818C2781197716 @default.
• W4382560818 hasConceptScore W4382560818C55493867 @default.
• W4382560818 hasConceptScore W4382560818C71924100 @default.
• W4382560818 hasConceptScore W4382560818C90924648 @default.
• W4382560818 hasFunder F4320310064 @default.
• W4382560818 hasIssue "13" @default.
• W4382560818 hasLocation W43825608181 @default.
• W4382560818 hasLocation W43825608182 @default.
• W4382560818 hasLocation W43825608183 @default.
• W4382560818 hasOpenAccess W4382560818 @default.
• W4382560818 hasPrimaryLocation W43825608181 @default.
• W4382560818 hasRelatedWork W1972654344 @default.
• W4382560818 hasRelatedWork W1977849899 @default.
• W4382560818 hasRelatedWork W2044755807 @default.
• W4382560818 hasRelatedWork W2096191357 @default.
• W4382560818 hasRelatedWork W2186316345 @default.
• W4382560818 hasRelatedWork W2301625460 @default.

• next