FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4382600488> ?p ?o ?g. }

• W4382600488 endingPage "1192" @default.
• W4382600488 startingPage "1181" @default.
• W4382600488 abstract "For patients with operable locally advanced esophageal carcinoma (LA-EC), we hypothesized that pre-operative induction chemotherapy followed by chemoradiotherapy (IC-CRT) would improve progression-free survival (PFS) and overall survival (OS) when compared to chemoradiotherapy (CRT).This was a single institution retrospective cohort study including patients with LA-EC who received preoperative-intent IC-CRT vs. CRT between 2013-2019. The Kaplan-Meier method was used to estimate OS and PFS. Cox proportional hazards regression was used to assess for variables associated with survival. The impact of treatment group on pathologic response was assessed by chi-square.Ninty-five patients were included for analysis (IC-CRT n=59; CRT n=36) and the median follow-up was 37.7 months (IQR: 16.8-56.1). There was no difference in median PFS or OS for IC-CRT or CRT, 22 months (95% CI: 12-59) vs. 32 months (95% CI: 10-57) (P=0.64) and 39 months (95% CI: 23-not reached) vs. 56.5 months (95% CI: 38-not reached) (P=0.36), respectively. Amongst the subset of patients with adenocarcinoma histology, there was no difference in median PFS or OS, nor was there when analyses were further restricted to those who received ≥3 cycles of induction 5-fluorouracil and platinum, or for those who underwent esophagectomy. Pathologic complete response occurred in 45% vs. 29% (P=0.24) and N-stage regression occurred in 72% vs. 58% (P=0.28) of patients in the IC-CRT and CRT cohorts, respectively. Distant metastasis occurred in 44% of patients in each treatment cohort.For patients with LA-EC, preoperative-intent IC-CRT was not associated with improved PFS or OS when compared with CRT." @default.
• W4382600488 created "2023-06-30" @default.
• W4382600488 creator A5006849637 @default.
• W4382600488 creator A5008456598 @default.
• W4382600488 creator A5012787104 @default.
• W4382600488 creator A5023485046 @default.
• W4382600488 creator A5029913877 @default.
• W4382600488 creator A5032041002 @default.
• W4382600488 creator A5042314992 @default.
• W4382600488 creator A5052643581 @default.
• W4382600488 creator A5053097984 @default.
• W4382600488 creator A5055159334 @default.
• W4382600488 creator A5056682593 @default.
• W4382600488 creator A5069279240 @default.
• W4382600488 creator A5083871900 @default.
• W4382600488 date "2023-06-01" @default.
• W4382600488 modified "2023-09-27" @default.
• W4382600488 title "Pre-operative chemoradiotherapy with or without induction chemotherapy for operable locally-advanced esophageal cancer" @default.
• W4382600488 cites W1922694287 @default.
• W4382600488 cites W2081203109 @default.
• W4382600488 cites W2127996441 @default.
• W4382600488 cites W2129300711 @default.
• W4382600488 cites W2132291148 @default.
• W4382600488 cites W2154444715 @default.
• W4382600488 cites W2333224485 @default.
• W4382600488 cites W2460848290 @default.
• W4382600488 cites W2517058999 @default.
• W4382600488 cites W2733330634 @default.
• W4382600488 cites W2938774982 @default.
• W4382600488 cites W3012051758 @default.
• W4382600488 cites W3148827278 @default.
• W4382600488 cites W3154482193 @default.
• W4382600488 cites W3158489862 @default.
• W4382600488 cites W3164767575 @default.
• W4382600488 cites W4226156918 @default.
• W4382600488 doi "https://doi.org/10.21037/jgo-22-1005" @default.
• W4382600488 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37435226" @default.
• W4382600488 hasPublicationYear "2023" @default.
• W4382600488 type Work @default.
• W4382600488 citedByCount "0" @default.
• W4382600488 crossrefType "journal-article" @default.
• W4382600488 hasAuthorship W4382600488A5006849637 @default.
• W4382600488 hasAuthorship W4382600488A5008456598 @default.
• W4382600488 hasAuthorship W4382600488A5012787104 @default.
• W4382600488 hasAuthorship W4382600488A5023485046 @default.
• W4382600488 hasAuthorship W4382600488A5029913877 @default.
• W4382600488 hasAuthorship W4382600488A5032041002 @default.
• W4382600488 hasAuthorship W4382600488A5042314992 @default.
• W4382600488 hasAuthorship W4382600488A5052643581 @default.
• W4382600488 hasAuthorship W4382600488A5053097984 @default.
• W4382600488 hasAuthorship W4382600488A5055159334 @default.
• W4382600488 hasAuthorship W4382600488A5056682593 @default.
• W4382600488 hasAuthorship W4382600488A5069279240 @default.
• W4382600488 hasAuthorship W4382600488A5083871900 @default.
• W4382600488 hasBestOaLocation W43826004881 @default.
• W4382600488 hasConcept C121608353 @default.
• W4382600488 hasConcept C126322002 @default.
• W4382600488 hasConcept C141071460 @default.
• W4382600488 hasConcept C146357865 @default.
• W4382600488 hasConcept C151730666 @default.
• W4382600488 hasConcept C167135981 @default.
• W4382600488 hasConcept C2776611710 @default.
• W4382600488 hasConcept C2776694085 @default.
• W4382600488 hasConcept C2777297899 @default.
• W4382600488 hasConcept C2778424827 @default.
• W4382600488 hasConcept C2779742542 @default.
• W4382600488 hasConcept C2781182431 @default.
• W4382600488 hasConcept C50382708 @default.
• W4382600488 hasConcept C71924100 @default.
• W4382600488 hasConcept C86803240 @default.
• W4382600488 hasConcept C90924648 @default.
• W4382600488 hasConceptScore W4382600488C121608353 @default.
• W4382600488 hasConceptScore W4382600488C126322002 @default.
• W4382600488 hasConceptScore W4382600488C141071460 @default.
• W4382600488 hasConceptScore W4382600488C146357865 @default.
• W4382600488 hasConceptScore W4382600488C151730666 @default.
• W4382600488 hasConceptScore W4382600488C167135981 @default.
• W4382600488 hasConceptScore W4382600488C2776611710 @default.
• W4382600488 hasConceptScore W4382600488C2776694085 @default.
• W4382600488 hasConceptScore W4382600488C2777297899 @default.
• W4382600488 hasConceptScore W4382600488C2778424827 @default.
• W4382600488 hasConceptScore W4382600488C2779742542 @default.
• W4382600488 hasConceptScore W4382600488C2781182431 @default.
• W4382600488 hasConceptScore W4382600488C50382708 @default.
• W4382600488 hasConceptScore W4382600488C71924100 @default.
• W4382600488 hasConceptScore W4382600488C86803240 @default.
• W4382600488 hasConceptScore W4382600488C90924648 @default.
• W4382600488 hasIssue "3" @default.
• W4382600488 hasLocation W43826004881 @default.
• W4382600488 hasLocation W43826004882 @default.
• W4382600488 hasLocation W43826004883 @default.
• W4382600488 hasOpenAccess W4382600488 @default.
• W4382600488 hasPrimaryLocation W43826004881 @default.
• W4382600488 hasRelatedWork W2024086237 @default.
• W4382600488 hasRelatedWork W2035430876 @default.
• W4382600488 hasRelatedWork W2078913685 @default.
• W4382600488 hasRelatedWork W2079792556 @default.
• W4382600488 hasRelatedWork W2084845148 @default.

• next