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- W4382631966 abstract "Mirikizumab (Omvoh®), a humanized IgG4 anti-human IL-23p19 monoclonal antibody, is being developed by Eli Lilly and Company Ltd for the treatment of ulcerative colitis and Crohn's disease. Mirikizumab was approved in March 2023 in Japan for use as induction and maintenance therapy in patients with moderate to severe ulcerative colitis who have an inadequate response to conventional therapy or therapies and is the first IL-23p19 inhibitor to be approved for this indication. Mirikizumab was granted a positive opinion in the EU in March 2023 for the treatment of adult patients with moderately to severely active UC who have had an inadequate response with, lost response to, or were intolerant to either conventional therapy or a biologic treatment. This article summarizes the milestones in the development of mirikizumab leading to this first approval for use in ulcerative colitis." @default.
- W4382631966 created "2023-07-01" @default.
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- W4382631966 date "2023-06-30" @default.
- W4382631966 modified "2023-10-14" @default.
- W4382631966 title "Mirikizumab: First Approval" @default.
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- W4382631966 doi "https://doi.org/10.1007/s40265-023-01909-1" @default.
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