Matches in SemOpenAlex for { <https://semopenalex.org/work/W4382632069> ?p ?o ?g. }
- W4382632069 abstract "Abstract The auditory cortex exerts a powerful, yet heterogeneous, effect on subcortical targets. Auditory corticofugal projections emanate from layers 5 and 6 and have complementary physiological properties. While several studies suggested that layer 5 corticofugal projections branch widely, others suggested that multiple independent projections exist. Less is known about layer 6; no studies have examined whether the various layer 6 corticofugal projections are independent. Therefore, we examined branching patterns of layers 5 and 6 auditory corticofugal neurons, using the corticocollicular system as an index, using traditional and novel approaches. We confirmed that dual retrograde injections into the mouse inferior colliculus and auditory thalamus co-labeled subpopulations of layers 5 and 6 auditory cortex neurons. We then used an intersectional approach to relabel layer 5 or 6 corticocollicular somata and found that both layers sent extensive branches to multiple subcortical structures. Using a novel approach to separately label layers 5 and 6 axons in individual mice, we found that layers 5 and 6 terminal distributions partially spatially overlapped and that giant terminals were only found in layer 5-derived axons. Overall, the high degree of branching and complementarity in layers 5 and 6 axonal distributions suggest that corticofugal projections should be considered as 2 widespread systems, rather than collections of individual projections." @default.
- W4382632069 created "2023-07-01" @default.
- W4382632069 creator A5014550871 @default.
- W4382632069 creator A5060781519 @default.
- W4382632069 creator A5063994814 @default.
- W4382632069 date "2023-06-29" @default.
- W4382632069 modified "2023-10-04" @default.
- W4382632069 title "Highly branched and complementary distributions of layer 5 and layer 6 auditory corticofugal axons in mouse" @default.
- W4382632069 cites W1633868817 @default.
- W4382632069 cites W1966692467 @default.
- W4382632069 cites W1971853010 @default.
- W4382632069 cites W1983254145 @default.
- W4382632069 cites W1983609681 @default.
- W4382632069 cites W1986287415 @default.
- W4382632069 cites W1988751134 @default.
- W4382632069 cites W1990859989 @default.
- W4382632069 cites W1993608927 @default.
- W4382632069 cites W1998791043 @default.
- W4382632069 cites W2000318517 @default.
- W4382632069 cites W2007541448 @default.
- W4382632069 cites W2007573724 @default.
- W4382632069 cites W2010613947 @default.
- W4382632069 cites W2011102093 @default.
- W4382632069 cites W2013422844 @default.
- W4382632069 cites W2016914301 @default.
- W4382632069 cites W2033999814 @default.
- W4382632069 cites W2037257325 @default.
- W4382632069 cites W2039252954 @default.
- W4382632069 cites W2041354598 @default.
- W4382632069 cites W2048827750 @default.
- W4382632069 cites W2051580272 @default.
- W4382632069 cites W2051781198 @default.
- W4382632069 cites W2069155994 @default.
- W4382632069 cites W2078770644 @default.
- W4382632069 cites W2080262020 @default.
- W4382632069 cites W2091111430 @default.
- W4382632069 cites W2092698625 @default.
- W4382632069 cites W2122131883 @default.
- W4382632069 cites W2125364686 @default.
- W4382632069 cites W2137801136 @default.
- W4382632069 cites W2141001421 @default.
- W4382632069 cites W2143066470 @default.
- W4382632069 cites W2144498728 @default.
- W4382632069 cites W2146639650 @default.
- W4382632069 cites W2147020027 @default.
- W4382632069 cites W2147335856 @default.
- W4382632069 cites W2151842870 @default.
- W4382632069 cites W2171526174 @default.
- W4382632069 cites W2263192676 @default.
- W4382632069 cites W2345340388 @default.
- W4382632069 cites W2358911592 @default.
- W4382632069 cites W2397734837 @default.
- W4382632069 cites W2522648513 @default.
- W4382632069 cites W2527794060 @default.
- W4382632069 cites W2546098128 @default.
- W4382632069 cites W2581460269 @default.
- W4382632069 cites W2625138568 @default.
- W4382632069 cites W2726651083 @default.
- W4382632069 cites W2789981464 @default.
- W4382632069 cites W2804230025 @default.
- W4382632069 cites W2809620273 @default.
- W4382632069 cites W2891485264 @default.
- W4382632069 cites W2901018059 @default.
- W4382632069 cites W2903257354 @default.
- W4382632069 cites W2952442589 @default.
- W4382632069 cites W3035497017 @default.
- W4382632069 cites W3044070454 @default.
- W4382632069 cites W3095081349 @default.
- W4382632069 cites W3121195200 @default.
- W4382632069 cites W3164950569 @default.
- W4382632069 cites W3166154691 @default.
- W4382632069 cites W3184611392 @default.
- W4382632069 cites W3194028368 @default.
- W4382632069 cites W3204721145 @default.
- W4382632069 cites W4226147925 @default.
- W4382632069 cites W4285719527 @default.
- W4382632069 cites W4307707398 @default.
- W4382632069 doi "https://doi.org/10.1093/cercor/bhad227" @default.
- W4382632069 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37386697" @default.
- W4382632069 hasPublicationYear "2023" @default.
- W4382632069 type Work @default.
- W4382632069 citedByCount "0" @default.
- W4382632069 crossrefType "journal-article" @default.
- W4382632069 hasAuthorship W4382632069A5014550871 @default.
- W4382632069 hasAuthorship W4382632069A5060781519 @default.
- W4382632069 hasAuthorship W4382632069A5063994814 @default.
- W4382632069 hasBestOaLocation W43826320691 @default.
- W4382632069 hasConcept C105702510 @default.
- W4382632069 hasConcept C169760540 @default.
- W4382632069 hasConcept C178790620 @default.
- W4382632069 hasConcept C185592680 @default.
- W4382632069 hasConcept C206175624 @default.
- W4382632069 hasConcept C2775980177 @default.
- W4382632069 hasConcept C2779227376 @default.
- W4382632069 hasConcept C2779246727 @default.
- W4382632069 hasConcept C2780297895 @default.
- W4382632069 hasConcept C2780723820 @default.
- W4382632069 hasConcept C2781416072 @default.
- W4382632069 hasConcept C2909708642 @default.
- W4382632069 hasConcept C86803240 @default.