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- W4382651879 abstract "Neoplasms are one of the most concerned public health problems worldwide. Digestive system neoplasms, with a high morbidity and mortality, is one of the most common malignant tumors in human being. It is found that exosomes act as an intercellular communication media to carry the metabolic and genetic information of parental cells to target cells. Likely, exosomes participate in lipid metabolism and regulates multiple processes in digestive system neoplasms, including the information transmission among cancer cells, the formation of neoplastic microenvironment, and the neoplastic biological behaviors like metastasis, invasion, and the chemotherapy resistance. In this review, we firstly introduce the main mechanisms whereas exosomes act as intercellular lipometabolic communication mediator in digestive system neoplasms. Thereafter we introduce the relationship between exosomes lipid metabolism and various type of digestive system neoplasms, including gastric cancer, hepatocellular carcinoma, pancreatic cancer, and colorectal cancer. Eventually, we summarized and prospected the development and implication of exosomes in digestive system neoplasms. The further research of exosomes as intercellular lipid metabolism mediator will contribute to accurate and efficient diagnosis and treatment of digestive system neoplasms." @default.
- W4382651879 created "2023-07-01" @default.
- W4382651879 creator A5004283796 @default.
- W4382651879 creator A5024225590 @default.
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- W4382651879 creator A5041963498 @default.
- W4382651879 creator A5076161122 @default.
- W4382651879 creator A5083559851 @default.
- W4382651879 date "2023-10-01" @default.
- W4382651879 modified "2023-10-12" @default.
- W4382651879 title "Exosomes: Another intercellular lipometabolic communication mediators in digestive system neoplasms?" @default.
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