FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4382657312> ?p ?o ?g. }

• W4382657312 abstract "Abstract Reactive steps are rapid responses after balance challenges. People with Parkinson's Disease demonstrate impaired reactive stepping, increasing fall risk. Although PwPD can improve steps through practice, the neural mechanisms contributing to improved reactive stepping in people with PD are poorly understood. This study investigated white-matter correlates of responsiveness to reactive step training in people with PD. Participants completed an eighteen-week multiple-baseline study consisting of two baseline assessments (B1 and B2) before training, a two-week, six-session training protocol, and two post-training assessments (immediate; P1) and two months after training (P2). Each assessment consisted of 3 backward reactive step trials. Outcomes included the anterior-posterior margin of stability, step length, and step latency. Tract-Based Spatial Statistics were performed to correlate white-matter microstructural integrity (fractional anisotropy and radial diffusivity) with retained improvements in reactive stepping at the two-month follow-up (P2–B2). Complete datasets were available from 22 participants. Greater retention of step length was associated with increased fractional anisotropy (better white-matter integrity) within the left anterior corona radiata (r = 0.54, p < 0.01), left posterior thalamic radiation (r = 0.54, p < 0.01), and right (r = 0.43, p = 0.04) and left (r = 0.0.40, p = 0.06) superior longitudinal fasciculi. Greater retention of step latency improvements was associated with lower radial diffusivity (greater white-matter integrity) within the left posterior (r = 0.60, p < 0.01) and anterior corona radiata (r = 0.61, p < 0.01). These findings highlight the importance of white-matter microstructural integrity in motor learning and retention processes in PD and may inform the development of targeted interventions to improve balance in people with PD." @default.
• W4382657312 created "2023-07-01" @default.
• W4382657312 creator A5010691893 @default.
• W4382657312 creator A5035778963 @default.
• W4382657312 creator A5064570269 @default.
• W4382657312 creator A5064864594 @default.
• W4382657312 date "2023-06-30" @default.
• W4382657312 modified "2023-09-26" @default.
• W4382657312 title "Associating White Matter Microstructural Integrity and Improvements in Reactive Stepping in People with Parkinson’s Disease" @default.
• W4382657312 cites W1964353232 @default.
• W4382657312 cites W1968770448 @default.
• W4382657312 cites W1977301501 @default.
• W4382657312 cites W1978657121 @default.
• W4382657312 cites W1982440006 @default.
• W4382657312 cites W1994438169 @default.
• W4382657312 cites W1996326513 @default.
• W4382657312 cites W2001757193 @default.
• W4382657312 cites W2003143331 @default.
• W4382657312 cites W2004492385 @default.
• W4382657312 cites W2006096283 @default.
• W4382657312 cites W2013410065 @default.
• W4382657312 cites W2021577902 @default.
• W4382657312 cites W2032284120 @default.
• W4382657312 cites W2046557060 @default.
• W4382657312 cites W2046634204 @default.
• W4382657312 cites W2049124973 @default.
• W4382657312 cites W2050451408 @default.
• W4382657312 cites W2061708164 @default.
• W4382657312 cites W2065291416 @default.
• W4382657312 cites W2071881327 @default.
• W4382657312 cites W2075788455 @default.
• W4382657312 cites W2088012901 @default.
• W4382657312 cites W2089989390 @default.
• W4382657312 cites W2099183578 @default.
• W4382657312 cites W2100508427 @default.
• W4382657312 cites W2102078998 @default.
• W4382657312 cites W2102384969 @default.
• W4382657312 cites W2106026803 @default.
• W4382657312 cites W2118015362 @default.
• W4382657312 cites W2118874222 @default.
• W4382657312 cites W2124094176 @default.
• W4382657312 cites W2139158372 @default.
• W4382657312 cites W2144073363 @default.
• W4382657312 cites W2145890464 @default.
• W4382657312 cites W2150667092 @default.
• W4382657312 cites W2151590528 @default.
• W4382657312 cites W2155486217 @default.
• W4382657312 cites W2156814615 @default.
• W4382657312 cites W2169618014 @default.
• W4382657312 cites W2207006693 @default.
• W4382657312 cites W2415536126 @default.
• W4382657312 cites W2588753636 @default.
• W4382657312 cites W2592611510 @default.
• W4382657312 cites W2765167702 @default.
• W4382657312 cites W2789774183 @default.
• W4382657312 cites W2811255424 @default.
• W4382657312 cites W2898210199 @default.
• W4382657312 cites W3035496018 @default.
• W4382657312 cites W3097521228 @default.
• W4382657312 cites W3098643515 @default.
• W4382657312 cites W3178646581 @default.
• W4382657312 cites W4241279990 @default.
• W4382657312 cites W4284971727 @default.
• W4382657312 cites W4296794109 @default.
• W4382657312 cites W4378952112 @default.
• W4382657312 cites W64770137 @default.
• W4382657312 doi "https://doi.org/10.21203/rs.3.rs-3117246/v1" @default.
• W4382657312 hasPublicationYear "2023" @default.
• W4382657312 type Work @default.
• W4382657312 citedByCount "0" @default.
• W4382657312 crossrefType "posted-content" @default.
• W4382657312 hasAuthorship W4382657312A5010691893 @default.
• W4382657312 hasAuthorship W4382657312A5035778963 @default.
• W4382657312 hasAuthorship W4382657312A5064570269 @default.
• W4382657312 hasAuthorship W4382657312A5064864594 @default.
• W4382657312 hasBestOaLocation W43826573121 @default.
• W4382657312 hasConcept C126322002 @default.
• W4382657312 hasConcept C126838900 @default.
• W4382657312 hasConcept C143409427 @default.
• W4382657312 hasConcept C149550507 @default.
• W4382657312 hasConcept C15744967 @default.
• W4382657312 hasConcept C164705383 @default.
• W4382657312 hasConcept C2778506634 @default.
• W4382657312 hasConcept C2778928357 @default.
• W4382657312 hasConcept C2780536345 @default.
• W4382657312 hasConcept C2781192897 @default.
• W4382657312 hasConcept C2989005 @default.
• W4382657312 hasConcept C71315377 @default.
• W4382657312 hasConcept C71924100 @default.
• W4382657312 hasConcept C89916169 @default.
• W4382657312 hasConcept C99508421 @default.
• W4382657312 hasConceptScore W4382657312C126322002 @default.
• W4382657312 hasConceptScore W4382657312C126838900 @default.
• W4382657312 hasConceptScore W4382657312C143409427 @default.
• W4382657312 hasConceptScore W4382657312C149550507 @default.
• W4382657312 hasConceptScore W4382657312C15744967 @default.
• W4382657312 hasConceptScore W4382657312C164705383 @default.
• W4382657312 hasConceptScore W4382657312C2778506634 @default.
• W4382657312 hasConceptScore W4382657312C2778928357 @default.
• W4382657312 hasConceptScore W4382657312C2780536345 @default.

• next