Matches in SemOpenAlex for { <https://semopenalex.org/work/W4382772083> ?p ?o ?g. }
Showing items 1 to 77 of
77
with 100 items per page.
- W4382772083 endingPage "445" @default.
- W4382772083 startingPage "445" @default.
- W4382772083 abstract "Arsenic is a potentially toxic agent for human health due to its widespread presence in the environment. Arsenic poisoning from drinking contaminated groundwater has become one of Bangladesh's most difficult healthcare problems. However, there is a lack of understanding of the detrimental impact of arsenic toxicity on children of arsenic-exposed parents. This study evaluates the effect of arsenic toxicity on body growth, blood parameters, and organ development of F1 mice. In this study, adult female mice were exposed to sodium arsenite from gestation day 12.5 until parturition, and then the postnatal growth, blood indices, and organ development were assessed. The result showed that from birth to weaning offspring of the sodium arsenite-treated group exhibited significant (p<0.002, p<0.0001, p<0.0001 consecutively) and weaning to sexual maturity of female offspring significantly (p<0.01, p<0.01, p<0.0001 respectively) slower increase in final body weight, total body weight gain, and rate of body weight gain than that of the offspring of the control group. Hematological tests revealed a significant reduction (p<0.03, p<0.02) in RBC and WBC count while significant elevation (p<0.02) in Platelet count, MCV, MCH, and MCHC in offspring of sodium arsenite exposed female mice than the offspring obtained from control female mice. RBS and Triglycerides levels were significantly higher (p<0.05, p<0.0008 respectively), while Alkaline phosphatase level was significantly lower (p<0.02) in the offspring of sodium arsenite-exposed female mice than in the offspring obtained from control female mice. In terms of organ-to-body weight ratio, the female F1 mice from the exposed group demonstrated a significantly lighter (p<0.01) kidney and heart as compared to that of the female F1 mice from the control group. Visual inspection of the organ morphology showed a slightly affected liver, lungs, and testes. Overall, the study suggests that inorganic arsenic exposure of the parent mice exerts harmful effects on the body growth, hematological and biochemical parameters, and organ morphology of the offspring." @default.
- W4382772083 created "2023-07-02" @default.
- W4382772083 creator A5005152794 @default.
- W4382772083 creator A5037588435 @default.
- W4382772083 creator A5043438190 @default.
- W4382772083 creator A5044442415 @default.
- W4382772083 date "2023-01-01" @default.
- W4382772083 modified "2023-09-28" @default.
- W4382772083 title "Inorganic arsenic exposure during pregnancy affects post-natal growth, blood parameters, and organ development of mice offspring" @default.
- W4382772083 doi "https://doi.org/10.5455/jabet.2023.d140" @default.
- W4382772083 hasPublicationYear "2023" @default.
- W4382772083 type Work @default.
- W4382772083 citedByCount "0" @default.
- W4382772083 crossrefType "journal-article" @default.
- W4382772083 hasAuthorship W4382772083A5005152794 @default.
- W4382772083 hasAuthorship W4382772083A5037588435 @default.
- W4382772083 hasAuthorship W4382772083A5043438190 @default.
- W4382772083 hasAuthorship W4382772083A5044442415 @default.
- W4382772083 hasBestOaLocation W43827720831 @default.
- W4382772083 hasConcept C112672928 @default.
- W4382772083 hasConcept C126322002 @default.
- W4382772083 hasConcept C134018914 @default.
- W4382772083 hasConcept C172507514 @default.
- W4382772083 hasConcept C178790620 @default.
- W4382772083 hasConcept C185592680 @default.
- W4382772083 hasConcept C2776305511 @default.
- W4382772083 hasConcept C2776630066 @default.
- W4382772083 hasConcept C2777764464 @default.
- W4382772083 hasConcept C2779234561 @default.
- W4382772083 hasConcept C2779495234 @default.
- W4382772083 hasConcept C2780655333 @default.
- W4382772083 hasConcept C29730261 @default.
- W4382772083 hasConcept C42407357 @default.
- W4382772083 hasConcept C46973012 @default.
- W4382772083 hasConcept C502230775 @default.
- W4382772083 hasConcept C54355233 @default.
- W4382772083 hasConcept C71924100 @default.
- W4382772083 hasConcept C86803240 @default.
- W4382772083 hasConceptScore W4382772083C112672928 @default.
- W4382772083 hasConceptScore W4382772083C126322002 @default.
- W4382772083 hasConceptScore W4382772083C134018914 @default.
- W4382772083 hasConceptScore W4382772083C172507514 @default.
- W4382772083 hasConceptScore W4382772083C178790620 @default.
- W4382772083 hasConceptScore W4382772083C185592680 @default.
- W4382772083 hasConceptScore W4382772083C2776305511 @default.
- W4382772083 hasConceptScore W4382772083C2776630066 @default.
- W4382772083 hasConceptScore W4382772083C2777764464 @default.
- W4382772083 hasConceptScore W4382772083C2779234561 @default.
- W4382772083 hasConceptScore W4382772083C2779495234 @default.
- W4382772083 hasConceptScore W4382772083C2780655333 @default.
- W4382772083 hasConceptScore W4382772083C29730261 @default.
- W4382772083 hasConceptScore W4382772083C42407357 @default.
- W4382772083 hasConceptScore W4382772083C46973012 @default.
- W4382772083 hasConceptScore W4382772083C502230775 @default.
- W4382772083 hasConceptScore W4382772083C54355233 @default.
- W4382772083 hasConceptScore W4382772083C71924100 @default.
- W4382772083 hasConceptScore W4382772083C86803240 @default.
- W4382772083 hasIssue "2" @default.
- W4382772083 hasLocation W43827720831 @default.
- W4382772083 hasOpenAccess W4382772083 @default.
- W4382772083 hasPrimaryLocation W43827720831 @default.
- W4382772083 hasRelatedWork W1985493312 @default.
- W4382772083 hasRelatedWork W2053734013 @default.
- W4382772083 hasRelatedWork W2095514708 @default.
- W4382772083 hasRelatedWork W2139614248 @default.
- W4382772083 hasRelatedWork W2147865078 @default.
- W4382772083 hasRelatedWork W2360765307 @default.
- W4382772083 hasRelatedWork W2811093047 @default.
- W4382772083 hasRelatedWork W3146296968 @default.
- W4382772083 hasRelatedWork W4296312248 @default.
- W4382772083 hasRelatedWork W2481579210 @default.
- W4382772083 hasVolume "6" @default.
- W4382772083 isParatext "false" @default.
- W4382772083 isRetracted "false" @default.
- W4382772083 workType "article" @default.