FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4382794083> ?p ?o ?g. }

• W4382794083 endingPage "6" @default.
• W4382794083 startingPage "1" @default.
• W4382794083 abstract "The serotonin system plays a critical role in the modulation of impulsive aggression. Although serotonin transporters (SERT) are key in modulating synaptic serotonin levels, few studies have investigated the role of SERT levels in human impulsive aggression. The aim of this study was to investigate whether brain SERT levels are associated with trait impulsive aggression. We included 148 healthy individuals (mean age 29.3 ± 13.0, range 18–80 years, 91 females) who had undergone positron emission positron (PET) examinations with the SERT tracer [11C]DASB and filled in self-report questionnaires of trait aggression, trait impulsivity and state aggression. We evaluated the association between cerebral SERT binding (BPND) and trait impulsive aggression in a latent variable model, with one latent variable (LVSERT) modelled from SERT BPND in frontostriatal and frontolimbic networks implicated in impulsive aggression, and another latent variable (LVIA) modelled from various trait measures of impulsivity and aggression. The LVSERT was not significantly associated with the LVIA (p = 0.8). Post-hoc univariate analyses did not reveal any significant associations between regional SERT levels and trait aggression, trait impulsivity or state aggression, but we found that state aggression at the day of PET scan was significantly lower in LA/LA homozygotes vs S-carriers of the 5-HTTLPR gene (p = 0.008). We conclude that brain SERT binding was not related to variations in trait impulsive aggression or state aggression. Our findings do not support that SERT is involved in mediating the serotonergic effects on aggression and impulsivity, at least not in individuals with non-pathological levels of impulsive aggression." @default.
• W4382794083 created "2023-07-02" @default.
• W4382794083 creator A5015895924 @default.
• W4382794083 creator A5015994033 @default.
• W4382794083 creator A5028671809 @default.
• W4382794083 creator A5029788021 @default.
• W4382794083 creator A5058269398 @default.
• W4382794083 creator A5027524946 @default.
• W4382794083 date "2023-09-01" @default.
• W4382794083 modified "2023-09-26" @default.
• W4382794083 title "The association between brain serotonin transporter binding and impulsivity and aggression in healthy individuals" @default.
• W4382794083 cites W1482357885 @default.
• W4382794083 cites W1510118021 @default.
• W4382794083 cites W1890188363 @default.
• W4382794083 cites W1933006075 @default.
• W4382794083 cites W1965407423 @default.
• W4382794083 cites W1966113261 @default.
• W4382794083 cites W1966464274 @default.
• W4382794083 cites W1981897480 @default.
• W4382794083 cites W1990005524 @default.
• W4382794083 cites W2002501515 @default.
• W4382794083 cites W2003382367 @default.
• W4382794083 cites W2003804842 @default.
• W4382794083 cites W2004644140 @default.
• W4382794083 cites W2005439203 @default.
• W4382794083 cites W2006679756 @default.
• W4382794083 cites W2017307521 @default.
• W4382794083 cites W2026395499 @default.
• W4382794083 cites W2029557523 @default.
• W4382794083 cites W2030773481 @default.
• W4382794083 cites W2033648104 @default.
• W4382794083 cites W2039453659 @default.
• W4382794083 cites W2067940063 @default.
• W4382794083 cites W2070861496 @default.
• W4382794083 cites W2073647577 @default.
• W4382794083 cites W2091953168 @default.
• W4382794083 cites W2102287498 @default.
• W4382794083 cites W2133151959 @default.
• W4382794083 cites W2137018799 @default.
• W4382794083 cites W2140905533 @default.
• W4382794083 cites W2294339574 @default.
• W4382794083 cites W2297942791 @default.
• W4382794083 cites W2300328345 @default.
• W4382794083 cites W2326803772 @default.
• W4382794083 cites W2592037022 @default.
• W4382794083 cites W2743107162 @default.
• W4382794083 cites W2775958664 @default.
• W4382794083 cites W2789366119 @default.
• W4382794083 cites W2886576293 @default.
• W4382794083 cites W2909457962 @default.
• W4382794083 cites W2946838583 @default.
• W4382794083 cites W2977322611 @default.
• W4382794083 cites W3164252487 @default.
• W4382794083 cites W4285032344 @default.
• W4382794083 cites W4292810003 @default.
• W4382794083 cites W4316042180 @default.
• W4382794083 doi "https://doi.org/10.1016/j.jpsychires.2023.06.023" @default.
• W4382794083 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37441926" @default.
• W4382794083 hasPublicationYear "2023" @default.
• W4382794083 type Work @default.
• W4382794083 citedByCount "0" @default.
• W4382794083 crossrefType "journal-article" @default.
• W4382794083 hasAuthorship W4382794083A5015895924 @default.
• W4382794083 hasAuthorship W4382794083A5015994033 @default.
• W4382794083 hasAuthorship W4382794083A5027524946 @default.
• W4382794083 hasAuthorship W4382794083A5028671809 @default.
• W4382794083 hasAuthorship W4382794083A5029788021 @default.
• W4382794083 hasAuthorship W4382794083A5058269398 @default.
• W4382794083 hasBestOaLocation W43827940831 @default.
• W4382794083 hasConcept C106934330 @default.
• W4382794083 hasConcept C118552586 @default.
• W4382794083 hasConcept C126322002 @default.
• W4382794083 hasConcept C138496976 @default.
• W4382794083 hasConcept C15744967 @default.
• W4382794083 hasConcept C170493617 @default.
• W4382794083 hasConcept C199360897 @default.
• W4382794083 hasConcept C2775864247 @default.
• W4382794083 hasConcept C2778897192 @default.
• W4382794083 hasConcept C2779448149 @default.
• W4382794083 hasConcept C2780319597 @default.
• W4382794083 hasConcept C3017944768 @default.
• W4382794083 hasConcept C37000724 @default.
• W4382794083 hasConcept C41008148 @default.
• W4382794083 hasConcept C70410870 @default.
• W4382794083 hasConcept C71924100 @default.
• W4382794083 hasConcept C99454951 @default.
• W4382794083 hasConceptScore W4382794083C106934330 @default.
• W4382794083 hasConceptScore W4382794083C118552586 @default.
• W4382794083 hasConceptScore W4382794083C126322002 @default.
• W4382794083 hasConceptScore W4382794083C138496976 @default.
• W4382794083 hasConceptScore W4382794083C15744967 @default.
• W4382794083 hasConceptScore W4382794083C170493617 @default.
• W4382794083 hasConceptScore W4382794083C199360897 @default.
• W4382794083 hasConceptScore W4382794083C2775864247 @default.
• W4382794083 hasConceptScore W4382794083C2778897192 @default.
• W4382794083 hasConceptScore W4382794083C2779448149 @default.
• W4382794083 hasConceptScore W4382794083C2780319597 @default.
• W4382794083 hasConceptScore W4382794083C3017944768 @default.

• next