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- W4382794423 abstract "Trabecular bone score (TBS) is a grey-level textural measurement acquired from dual-energy X-ray absorptiometry lumbar spine images and is a validated index of bone microarchitecture. In 2015, a Working Group of the European Society on Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO) published a review of the TBS literature, concluding that TBS predicts hip and major osteoporotic fracture, at least partly independent of bone mineral density (BMD) and clinical risk factors. It was also concluded that TBS is potentially amenable to change as a result of pharmacological therapy. Further evidence on the utility of TBS has since accumulated in both primary and secondary osteoporosis, and the introduction of FRAX and BMD T-score adjustment for TBS has accelerated adoption. This position paper therefore presents a review of the updated scientific literature and provides expert consensus statements and corresponding operational guidelines for the use of TBS.An Expert Working Group was convened by the ESCEO and a systematic review of the evidence undertaken, with defined search strategies for four key topics with respect to the potential use of TBS: (1) fracture prediction in men and women; (2) initiating and monitoring treatment in postmenopausal osteoporosis; (3) fracture prediction in secondary osteoporosis; and (4) treatment monitoring in secondary osteoporosis. Statements to guide the clinical use of TBS were derived from the review and graded by consensus using the Grades of Recommendation, Assessment, Development and Evaluation (GRADE) approach.A total of 96 articles were reviewed and included data on the use of TBS for fracture prediction in men and women, from over 20 countries. The updated evidence shows that TBS enhances fracture risk prediction in both primary and secondary osteoporosis, and can, when taken with BMD and clinical risk factors, inform treatment initiation and the choice of antiosteoporosis treatment. Evidence also indicates that TBS provides useful adjunctive information in monitoring treatment with long-term denosumab and anabolic agents. All expert consensus statements were voted as strongly recommended.The addition of TBS assessment to FRAX and/or BMD enhances fracture risk prediction in primary and secondary osteoporosis, adding useful information for treatment decision-making and monitoring. The expert consensus statements provided in this paper can be used to guide the integration of TBS in clinical practice for the assessment and management of osteoporosis. An example of an operational approach is provided in the appendix. This position paper presents an up-to-date review of the evidence base, synthesised through expert consensus statements, which informs the implementation of Trabecular Bone Score in clinical practice." @default.
- W4382794423 created "2023-07-02" @default.
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- W4382794423 date "2023-07-01" @default.
- W4382794423 modified "2023-10-15" @default.
- W4382794423 title "Update on the clinical use of trabecular bone score (TBS) in the management of osteoporosis: results of an expert group meeting organized by the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO), and the International Osteoporosis Foundation (IOF) under the auspices of WHO Collaborating Center for Epidemiology of Musculoskeletal Health and Aging" @default.
- W4382794423 cites W1564292649 @default.
- W4382794423 cites W1855745621 @default.
- W4382794423 cites W1864817521 @default.
- W4382794423 cites W1910825678 @default.
- W4382794423 cites W1932974168 @default.
- W4382794423 cites W1939179845 @default.
- W4382794423 cites W1968709197 @default.
- W4382794423 cites W1969650383 @default.
- W4382794423 cites W1970310498 @default.
- W4382794423 cites W1970933583 @default.
- W4382794423 cites W1972567404 @default.
- W4382794423 cites W1980674181 @default.
- W4382794423 cites W1982691273 @default.
- W4382794423 cites W1983211249 @default.
- W4382794423 cites W1985576983 @default.
- W4382794423 cites W1987125795 @default.
- W4382794423 cites W1993345945 @default.
- W4382794423 cites W1993490449 @default.
- W4382794423 cites W1997501144 @default.
- W4382794423 cites W1997823019 @default.
- W4382794423 cites W1997903603 @default.
- W4382794423 cites W2007509998 @default.
- W4382794423 cites W2012406283 @default.
- W4382794423 cites W2022836308 @default.
- W4382794423 cites W2028209514 @default.
- W4382794423 cites W2030593008 @default.
- W4382794423 cites W2034127373 @default.
- W4382794423 cites W2052769264 @default.
- W4382794423 cites W2057964471 @default.
- W4382794423 cites W2077605862 @default.
- W4382794423 cites W2083977140 @default.
- W4382794423 cites W2092654589 @default.
- W4382794423 cites W2096074908 @default.
- W4382794423 cites W2102265912 @default.
- W4382794423 cites W2109260966 @default.
- W4382794423 cites W2110224271 @default.
- W4382794423 cites W2120940916 @default.
- W4382794423 cites W2123817219 @default.
- W4382794423 cites W2128977360 @default.
- W4382794423 cites W2145070208 @default.
- W4382794423 cites W2153579902 @default.
- W4382794423 cites W2161540044 @default.
- W4382794423 cites W2163554085 @default.
- W4382794423 cites W2168637297 @default.
- W4382794423 cites W2170022091 @default.
- W4382794423 cites W2177878526 @default.
- W4382794423 cites W2178491029 @default.
- W4382794423 cites W2306653874 @default.
- W4382794423 cites W2337927483 @default.
- W4382794423 cites W2342793300 @default.
- W4382794423 cites W2343321299 @default.
- W4382794423 cites W2406459505 @default.
- W4382794423 cites W2460787155 @default.
- W4382794423 cites W2482825522 @default.
- W4382794423 cites W2487232386 @default.
- W4382794423 cites W2507761091 @default.
- W4382794423 cites W2518294421 @default.
- W4382794423 cites W2520995084 @default.
- W4382794423 cites W2528722633 @default.
- W4382794423 cites W2529929498 @default.
- W4382794423 cites W2534555159 @default.
- W4382794423 cites W2534811248 @default.
- W4382794423 cites W2563286383 @default.
- W4382794423 cites W2563919593 @default.
- W4382794423 cites W2575315472 @default.
- W4382794423 cites W2589534134 @default.
- W4382794423 cites W2594856800 @default.
- W4382794423 cites W2595277360 @default.
- W4382794423 cites W2599867508 @default.
- W4382794423 cites W2619068688 @default.
- W4382794423 cites W2621710835 @default.
- W4382794423 cites W2621975031 @default.
- W4382794423 cites W2626568597 @default.
- W4382794423 cites W2738621753 @default.
- W4382794423 cites W2752949102 @default.
- W4382794423 cites W2755447733 @default.
- W4382794423 cites W2759500334 @default.