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• W4382794513 endingPage "136780" @default.
• W4382794513 startingPage "136780" @default.
• W4382794513 abstract "Foodborne illness caused by Staphylococcus aureus (S. aureus) has posed a significant threat to human health. Herein, an integrated multifunctional nanoplatform was developed for fluorescence detection and inactivation of S. aureus based on cascade signal amplification coupled with single strand DNA-template copper nanoparticles (ssDNA-Cu NPs). Benefiting from reasonable design, one-step cascade signal amplification was achieved through strand displacement amplification combined with rolling circle amplification, followed by in-situ generation of copper nanoparticles. S. aureus detection could be performed through naked eye observation and microplate reader measurement of the red fluorescence signal. The multifunctional nanoplatform had satisfactory specificity and sensitivity, achieving 5.2 CFU mL-1 detection limit and successful detection of 7.3 CFU of S. aureus in spiked egg after < 5 h of enrichment. Moreover, ssDNA-Cu NPs could eliminate S. aureus to avoid secondary bacterial contamination without further treatment. Therefore, this multifunctional nanoplatform has potential application in food safety dtection." @default.
• W4382794513 created "2023-07-02" @default.
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• W4382794513 date "2023-12-01" @default.
• W4382794513 modified "2023-10-05" @default.
• W4382794513 title "Integrated multifunctional nanoplatform for fluorescence detection and inactivation of Staphylococcus aureus" @default.
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• W4382794513 doi "https://doi.org/10.1016/j.foodchem.2023.136780" @default.
• W4382794513 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37413833" @default.
• W4382794513 hasPublicationYear "2023" @default.
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