Matches in SemOpenAlex for { <https://semopenalex.org/work/W4382894171> ?p ?o ?g. }
Showing items 1 to 84 of
84
with 100 items per page.
- W4382894171 endingPage "775" @default.
- W4382894171 startingPage "762" @default.
- W4382894171 abstract "Background: Previous studies have found a potential role for statins in liver cancer prevention. Objective: This study aimed to explore the effect of different types of statins on the incidence of liver cancer. Methods: Relevant articles were systematically retrieved from PubMed, EBSCO, Web of Science, and Cochrane Library databases from inception until July 2022 to explore the relationship between lipophilic statins or hydrophilic statins exposure and the incidence of liver cancer. The main outcome was the incidence of liver cancer. Results: Eleven articles were included in this meta-analysis. The pooled results showed a reduced incidence of liver cancer in patients exposed to lipophilic statins (OR=0.54, p & 0.001) and hydrophilic statins (OR=0.56, p & 0.001) compared with the non-exposed cohort. Subgroup analysis showed that both exposures to lipophilic (Eastern countries: OR=0.51, p & 0.001; Western countries: OR=0.59, p & 0.001) and hydrophilic (Eastern countries: OR=0.51, p & 0.001; Western countries: OR=0.66, p=0.019) statins reduced the incidence of liver cancer in Eastern and Western countries, and the reduction was most significant in Eastern countries. Moreover, atorvastatin (OR=0.55, p & 0.001), simvastatin (OR=0.59, p & 0.001), lovastatin (OR=0.51, p & 0.001), pitavastatin (OR=0.36, p=0.008) and rosuvastatin (OR=0.60, p=0.027) could effectively reduce the incidence of liver cancer, unlike fluvastatin, cerivastatin and pravastatin. Conclusion: Both lipophilic and hydrophilic statins contribute to the prevention of liver cancer. Moreover, the efficacy was influenced by the region and the specific type of statins used." @default.
- W4382894171 created "2023-07-03" @default.
- W4382894171 creator A5000007063 @default.
- W4382894171 creator A5011040894 @default.
- W4382894171 creator A5031829937 @default.
- W4382894171 creator A5048956463 @default.
- W4382894171 creator A5062671459 @default.
- W4382894171 creator A5088615179 @default.
- W4382894171 date "2024-02-01" @default.
- W4382894171 modified "2023-10-12" @default.
- W4382894171 title "Association between Statins Types with Incidence of Liver Cancer: An Updated Meta-analysis" @default.
- W4382894171 doi "https://doi.org/10.2174/0929867330666230701000400" @default.
- W4382894171 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37393552" @default.
- W4382894171 hasPublicationYear "2024" @default.
- W4382894171 type Work @default.
- W4382894171 citedByCount "0" @default.
- W4382894171 countsByYear W43828941712023 @default.
- W4382894171 crossrefType "journal-article" @default.
- W4382894171 hasAuthorship W4382894171A5000007063 @default.
- W4382894171 hasAuthorship W4382894171A5011040894 @default.
- W4382894171 hasAuthorship W4382894171A5031829937 @default.
- W4382894171 hasAuthorship W4382894171A5048956463 @default.
- W4382894171 hasAuthorship W4382894171A5062671459 @default.
- W4382894171 hasAuthorship W4382894171A5088615179 @default.
- W4382894171 hasBestOaLocation W43828941711 @default.
- W4382894171 hasConcept C120665830 @default.
- W4382894171 hasConcept C121332964 @default.
- W4382894171 hasConcept C121608353 @default.
- W4382894171 hasConcept C126322002 @default.
- W4382894171 hasConcept C2776231280 @default.
- W4382894171 hasConcept C2776329913 @default.
- W4382894171 hasConcept C2776692505 @default.
- W4382894171 hasConcept C2776839432 @default.
- W4382894171 hasConcept C2777482532 @default.
- W4382894171 hasConcept C2778163477 @default.
- W4382894171 hasConcept C2778417548 @default.
- W4382894171 hasConcept C2779519902 @default.
- W4382894171 hasConcept C2780499067 @default.
- W4382894171 hasConcept C2780940807 @default.
- W4382894171 hasConcept C2992704333 @default.
- W4382894171 hasConcept C61511704 @default.
- W4382894171 hasConcept C71924100 @default.
- W4382894171 hasConcept C90924648 @default.
- W4382894171 hasConcept C98274493 @default.
- W4382894171 hasConceptScore W4382894171C120665830 @default.
- W4382894171 hasConceptScore W4382894171C121332964 @default.
- W4382894171 hasConceptScore W4382894171C121608353 @default.
- W4382894171 hasConceptScore W4382894171C126322002 @default.
- W4382894171 hasConceptScore W4382894171C2776231280 @default.
- W4382894171 hasConceptScore W4382894171C2776329913 @default.
- W4382894171 hasConceptScore W4382894171C2776692505 @default.
- W4382894171 hasConceptScore W4382894171C2776839432 @default.
- W4382894171 hasConceptScore W4382894171C2777482532 @default.
- W4382894171 hasConceptScore W4382894171C2778163477 @default.
- W4382894171 hasConceptScore W4382894171C2778417548 @default.
- W4382894171 hasConceptScore W4382894171C2779519902 @default.
- W4382894171 hasConceptScore W4382894171C2780499067 @default.
- W4382894171 hasConceptScore W4382894171C2780940807 @default.
- W4382894171 hasConceptScore W4382894171C2992704333 @default.
- W4382894171 hasConceptScore W4382894171C61511704 @default.
- W4382894171 hasConceptScore W4382894171C71924100 @default.
- W4382894171 hasConceptScore W4382894171C90924648 @default.
- W4382894171 hasConceptScore W4382894171C98274493 @default.
- W4382894171 hasIssue "6" @default.
- W4382894171 hasLocation W43828941711 @default.
- W4382894171 hasLocation W43828941712 @default.
- W4382894171 hasOpenAccess W4382894171 @default.
- W4382894171 hasPrimaryLocation W43828941711 @default.
- W4382894171 hasRelatedWork W1841146742 @default.
- W4382894171 hasRelatedWork W1983512991 @default.
- W4382894171 hasRelatedWork W2048086967 @default.
- W4382894171 hasRelatedWork W2127232229 @default.
- W4382894171 hasRelatedWork W2323501455 @default.
- W4382894171 hasRelatedWork W2367156482 @default.
- W4382894171 hasRelatedWork W2372513369 @default.
- W4382894171 hasRelatedWork W2415531687 @default.
- W4382894171 hasRelatedWork W2997726045 @default.
- W4382894171 hasRelatedWork W4291819813 @default.
- W4382894171 hasVolume "31" @default.
- W4382894171 isParatext "false" @default.
- W4382894171 isRetracted "false" @default.
- W4382894171 workType "article" @default.