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- W4382896475 abstract "Thyroid products are used in the treatment of hypothyroidism, myxedema coma, and suppression of pituitary thyroid stimulating hormone. Normally, the thyroid gland produces the hormones triiodothyronine (T3) and thyroxine (T4). When not enough of these hormones are produced metabolism, growth and development are affected. Levothyroxine, a synthetic form of T4 is the preferred therapeutic agent to treat hypothyroidism. Liothyronine is another thyroid hormone used to treat hypothyroidism. This drug is a synthetic form of triiodothyronine (T3). Thyroid, a dried and powdered form of thyroid gland obtained from animals has been determined by the US Food and Drug Administration (FDA) to not be safe and effective in treating hypothyroidism and the drug product labeling has not been approved by the FDA. Both levothyroxine and liothyronine are available in solid oral dosage forms in addition to parenteral solutions. Some adverse effects reported with use of these thyroid preparations include alopecia (hair loss), excessive sweating, diarrhea, weight loss, insomnia, anxiety, nervousness, and fatigue. Studies have found an increased risk of fracture in the elderly population and increased incidence of bone loss in postmenopausal women on thyroid supplements. Exposure to thyroid drug products, both intentional and accidental, is common but clinical effects are rare." @default.
- W4382896475 created "2023-07-03" @default.
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- W4382896475 date "2023-01-01" @default.
- W4382896475 modified "2023-10-18" @default.
- W4382896475 title "Thyroid preparations" @default.
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- W4382896475 doi "https://doi.org/10.1016/b978-0-12-824315-2.00959-3" @default.
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