Matches in SemOpenAlex for { <https://semopenalex.org/work/W4382896655> ?p ?o ?g. }
Showing items 1 to 99 of
99
with 100 items per page.
- W4382896655 endingPage "420" @default.
- W4382896655 startingPage "411" @default.
- W4382896655 abstract "Multi-walled carbon nanotubes (MWCNTs), a kind of nanomaterial, are widely used in battery electrodes and composite materials, but the adverse effects associated with their accumulation in the living body have not been sufficiently investigated. MWCNTs are a fibrous material with molecules similar to asbestos fibers, and there are concerns about its effects on the respiratory system. In this study, we conducted a risk assessment by exposing mice using a previously developed nanomaterial inhalation exposure method. We quantified the exposure in the lungs by a lung burden test, evaluated the deterioration due to pneumonia using respiratory syncytial virus (RSV) infection, and measured inflammatory cytokines in bronchoalveolar lavage fluid (BALF). As a result, in the lung burden test, the amount of MWCNT in the lung increased according to the inhalation dose. In the RSV infection experiment, CCL3, CCL5, and TGF-β, which are indicators of inflammation and lung fibrosis, were elevated in the MWCNT-exposed group. Histological examination revealed cells phagocytosing MWCNT fibers. These phagocytic cells were also seen during the recovery period from RSV infection. The present study found that MWCNT remained in the lungs for about a month or more, suggesting that the fibers may continue to exert immunological effects on the respiratory system. Furthermore, the inhalation exposure method enabled the exposure of nanomaterials to the entire lung lobe, allowing a more detailed evaluation of the effects on the respiratory system." @default.
- W4382896655 created "2023-07-03" @default.
- W4382896655 creator A5002181761 @default.
- W4382896655 creator A5008576503 @default.
- W4382896655 creator A5013485509 @default.
- W4382896655 creator A5025682247 @default.
- W4382896655 creator A5042610324 @default.
- W4382896655 creator A5050514967 @default.
- W4382896655 creator A5056941513 @default.
- W4382896655 creator A5085709435 @default.
- W4382896655 creator A5089394910 @default.
- W4382896655 date "2023-01-01" @default.
- W4382896655 modified "2023-09-26" @default.
- W4382896655 title "Effects of inhalation of multi-walled carbon nanotube (MWCNT) on respiratory syncytial virus (RSV) infection in mice" @default.
- W4382896655 cites W1975059364 @default.
- W4382896655 cites W1981728150 @default.
- W4382896655 cites W1991901434 @default.
- W4382896655 cites W2029445495 @default.
- W4382896655 cites W2039660500 @default.
- W4382896655 cites W2046315474 @default.
- W4382896655 cites W2052447210 @default.
- W4382896655 cites W2102498199 @default.
- W4382896655 cites W2119538646 @default.
- W4382896655 cites W2138003976 @default.
- W4382896655 cites W2147516417 @default.
- W4382896655 cites W2148259790 @default.
- W4382896655 cites W2162551101 @default.
- W4382896655 cites W2463738079 @default.
- W4382896655 cites W2519380019 @default.
- W4382896655 cites W2558274900 @default.
- W4382896655 cites W2612889958 @default.
- W4382896655 cites W2769743733 @default.
- W4382896655 cites W2947649415 @default.
- W4382896655 cites W2976660161 @default.
- W4382896655 cites W3117522827 @default.
- W4382896655 cites W3169709719 @default.
- W4382896655 cites W3215829030 @default.
- W4382896655 cites W4200484612 @default.
- W4382896655 doi "https://doi.org/10.2131/jts.48.411" @default.
- W4382896655 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37394654" @default.
- W4382896655 hasPublicationYear "2023" @default.
- W4382896655 type Work @default.
- W4382896655 citedByCount "0" @default.
- W4382896655 crossrefType "journal-article" @default.
- W4382896655 hasAuthorship W4382896655A5002181761 @default.
- W4382896655 hasAuthorship W4382896655A5008576503 @default.
- W4382896655 hasAuthorship W4382896655A5013485509 @default.
- W4382896655 hasAuthorship W4382896655A5025682247 @default.
- W4382896655 hasAuthorship W4382896655A5042610324 @default.
- W4382896655 hasAuthorship W4382896655A5050514967 @default.
- W4382896655 hasAuthorship W4382896655A5056941513 @default.
- W4382896655 hasAuthorship W4382896655A5085709435 @default.
- W4382896655 hasAuthorship W4382896655A5089394910 @default.
- W4382896655 hasBestOaLocation W43828966551 @default.
- W4382896655 hasConcept C126322002 @default.
- W4382896655 hasConcept C142724271 @default.
- W4382896655 hasConcept C203014093 @default.
- W4382896655 hasConcept C2776954882 @default.
- W4382896655 hasConcept C2777714996 @default.
- W4382896655 hasConcept C2777914695 @default.
- W4382896655 hasConcept C2777961210 @default.
- W4382896655 hasConcept C2779777708 @default.
- W4382896655 hasConcept C2780559512 @default.
- W4382896655 hasConcept C42219234 @default.
- W4382896655 hasConcept C534529494 @default.
- W4382896655 hasConcept C71924100 @default.
- W4382896655 hasConceptScore W4382896655C126322002 @default.
- W4382896655 hasConceptScore W4382896655C142724271 @default.
- W4382896655 hasConceptScore W4382896655C203014093 @default.
- W4382896655 hasConceptScore W4382896655C2776954882 @default.
- W4382896655 hasConceptScore W4382896655C2777714996 @default.
- W4382896655 hasConceptScore W4382896655C2777914695 @default.
- W4382896655 hasConceptScore W4382896655C2777961210 @default.
- W4382896655 hasConceptScore W4382896655C2779777708 @default.
- W4382896655 hasConceptScore W4382896655C2780559512 @default.
- W4382896655 hasConceptScore W4382896655C42219234 @default.
- W4382896655 hasConceptScore W4382896655C534529494 @default.
- W4382896655 hasConceptScore W4382896655C71924100 @default.
- W4382896655 hasIssue "7" @default.
- W4382896655 hasLocation W43828966551 @default.
- W4382896655 hasLocation W43828966552 @default.
- W4382896655 hasOpenAccess W4382896655 @default.
- W4382896655 hasPrimaryLocation W43828966551 @default.
- W4382896655 hasRelatedWork W1965378536 @default.
- W4382896655 hasRelatedWork W2004431782 @default.
- W4382896655 hasRelatedWork W2015314828 @default.
- W4382896655 hasRelatedWork W2023862382 @default.
- W4382896655 hasRelatedWork W2029283892 @default.
- W4382896655 hasRelatedWork W2155008140 @default.
- W4382896655 hasRelatedWork W2384085853 @default.
- W4382896655 hasRelatedWork W4231263229 @default.
- W4382896655 hasRelatedWork W4320489806 @default.
- W4382896655 hasRelatedWork W4382896655 @default.
- W4382896655 hasVolume "48" @default.
- W4382896655 isParatext "false" @default.
- W4382896655 isRetracted "false" @default.
- W4382896655 workType "article" @default.