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• W4382930716 abstract "Abstract Backgroud: COVID-19 was recognized a public health issue and SARS-CoV-2 was assumed to infect human ovary and cross the blood–testis barrier. Method: To explore the infection of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in patients’ semen and follicular fluid and its potential clinical outcome. Ten female patients with an average age of 30.7±4.11years and eight male patients with an average age of 32.13±4.45 years diagnosed with COVID-19 and their spouses were negative to COVID-19 were included. Results: None of ten male and 8 female patients with COVID-19 affecting was absence of SARS-CoV-2 RNA in semen and follicular fluid. The sperm parameters, the rates of oocytes maturation, fertilization, cleavage and blastulation between the control and test group was not statistically significant (P>0.05),but the sperm quality, the oocyte maturation and fertilization, the blastulation showed a decline tendency in COVID-19 affected patients. Conclusion: COVID-19 affection may have an uncertian negative influence on the gamete quality and embryo development. Our new knowledge will help to evaluate the impact of COVID-19 on fertility in virus infected patients." @default.
• W4382930716 created "2023-07-04" @default.
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• W4382930716 date "2023-07-03" @default.
• W4382930716 modified "2023-09-26" @default.
• W4382930716 title "Impact of COVID-19 on gamete quality and embryo development in patients with COVID-19 positive undergoing ART" @default.
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• W4382930716 doi "https://doi.org/10.21203/rs.3.rs-3088255/v1" @default.
• W4382930716 hasPublicationYear "2023" @default.
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