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- W4382930907 abstract "Abstract Dissecting genetic components in crop plants associated with heat stress (HS) sensing and adaptation will facilitate the design of modern crop varieties with improved thermotolerance. However, the molecular mechanisms underlying the ON/OFF switch controlling HS responses (HSRs) in wheat (Triticum aestivum) remain largely unknown. In this study, we focused on the molecular action of TaHsfA1, a class A heat shock transcription factor, in sensing dynamically changing HS signals and regulating HSRs. We show that the TaHsfA1 protein is modified by small ubiquitin–related modifier (SUMO) and that this modification is essential for the full transcriptional activation activity of TaHsfA1 in triggering downstream gene expression. During sustained heat exposure, the SUMOylation of TaHsfA1 is suppressed, which partially reduces TaHsfA1 protein activity, thereby reducing the intensity of downstream HSRs. In addition, we demonstrate that TaHsfA1 interacts with the histone acetyltransferase TaHAG1 in a thermosensitive manner. Together, our findings emphasize the importance of TaHsfA1 in thermotolerance in wheat. In addition, they define a highly dynamic SUMOylation-dependent “ON/OFF” molecular switch that senses temperature signals and contributes to thermotolerance in crops." @default.
- W4382930907 created "2023-07-04" @default.
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- W4382930907 date "2023-07-03" @default.
- W4382930907 modified "2023-10-17" @default.
- W4382930907 title "Thermosensitive SUMOylation of TaHsfA1 defines a dynamic ON/OFF molecular switch for the heat stress response in wheat" @default.
- W4382930907 cites W1941634103 @default.
- W4382930907 cites W1964604281 @default.
- W4382930907 cites W1971656831 @default.
- W4382930907 cites W1977910682 @default.
- W4382930907 cites W1983232279 @default.
- W4382930907 cites W1988848780 @default.
- W4382930907 cites W1995800711 @default.
- W4382930907 cites W1998053175 @default.
- W4382930907 cites W1998409099 @default.
- W4382930907 cites W1999132225 @default.
- W4382930907 cites W2003199010 @default.
- W4382930907 cites W2027681868 @default.
- W4382930907 cites W2034728759 @default.
- W4382930907 cites W2036051630 @default.
- W4382930907 cites W2052821301 @default.
- W4382930907 cites W2059524588 @default.
- W4382930907 cites W2084795601 @default.
- W4382930907 cites W2093260830 @default.
- W4382930907 cites W2097828379 @default.
- W4382930907 cites W2100090579 @default.
- W4382930907 cites W2114587202 @default.
- W4382930907 cites W2117500376 @default.
- W4382930907 cites W2118476033 @default.
- W4382930907 cites W2122638323 @default.
- W4382930907 cites W2125422443 @default.
- W4382930907 cites W2133825089 @default.
- W4382930907 cites W2134030532 @default.
- W4382930907 cites W2137068170 @default.
- W4382930907 cites W2137920653 @default.
- W4382930907 cites W2141616193 @default.
- W4382930907 cites W2143658931 @default.
- W4382930907 cites W2144175569 @default.
- W4382930907 cites W2145327656 @default.
- W4382930907 cites W2148302985 @default.
- W4382930907 cites W2152622809 @default.
- W4382930907 cites W2164190556 @default.
- W4382930907 cites W2165016943 @default.
- W4382930907 cites W2169456326 @default.
- W4382930907 cites W2170681743 @default.
- W4382930907 cites W2179438025 @default.
- W4382930907 cites W2220195221 @default.
- W4382930907 cites W2241265010 @default.
- W4382930907 cites W2521298391 @default.
- W4382930907 cites W2565989833 @default.
- W4382930907 cites W2739174192 @default.
- W4382930907 cites W2747319455 @default.
- W4382930907 cites W2776449119 @default.
- W4382930907 cites W2794718451 @default.
- W4382930907 cites W2799524357 @default.
- W4382930907 cites W2883163517 @default.
- W4382930907 cites W2883876921 @default.
- W4382930907 cites W2886748374 @default.
- W4382930907 cites W2886785109 @default.
- W4382930907 cites W2900162847 @default.
- W4382930907 cites W2907177719 @default.
- W4382930907 cites W2914160403 @default.
- W4382930907 cites W2940732487 @default.
- W4382930907 cites W2946749387 @default.
- W4382930907 cites W2965221299 @default.
- W4382930907 cites W2968699971 @default.
- W4382930907 cites W2971643529 @default.
- W4382930907 cites W3012604830 @default.
- W4382930907 cites W3016560093 @default.
- W4382930907 cites W3025489472 @default.
- W4382930907 cites W3089071526 @default.
- W4382930907 cites W3108775845 @default.
- W4382930907 cites W3123474156 @default.
- W4382930907 cites W3124407151 @default.
- W4382930907 cites W3125254537 @default.
- W4382930907 cites W3156458251 @default.
- W4382930907 cites W3199730086 @default.
- W4382930907 cites W3212334707 @default.
- W4382930907 cites W3216499640 @default.
- W4382930907 cites W4283691254 @default.
- W4382930907 cites W4296935148 @default.