FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4382931034> ?p ?o ?g. }

• W4382931034 abstract "Via complex salivary mixture, mosquitos can intervene immune response and be helpful to transmit several viruses causing deadly human diseases. Some C-type lectins (CTLs) of mosquito have been reported to be pattern recognition receptor to either resist or promote pathogen invading. Here, we investigated the expression profile and agglutination function of an Aedes albopictus CTL (Aalb_CTL2) carrying a single carbohydrate-recognition domain (CRD) and WND/KPD motifs. The results showed that Aalb_CTL2 was found to be specifically expressed in mosquito saliva gland and its expression was not induced by blood-feeding. The recombinant Aalb_CTL2 (rAalb_CTL2) could agglutinate mouse erythrocytes in the presence of calcium and the agglutinating activity could be inhibited by EDTA. rAalb_CTL2 also displayed the sugar binding ability to D-mannose, D-galactose, D-glucose, and maltose. Furthermore, it was demonstrated that rAalb_CTL2 could bind and agglutinate Gram positive bacteria Staphylococcus aureus and Bacillus subtilis, Gram negative bacteria Escherichia coli and Pseudomonas aeruginosa, as well as fungus Candida albicans in vitro in a calcium dependent manner. However, rAalb_CTL2 could not promote type 2 dengue virus (DENV-2) replication in THP-1 and BHK-21 cell lines. These findings uncover that Aalb_CTL2 might be involved in the innate immunity of mosquito to resist microorganism multiplication in sugar and blood meals to help mosquito survive in the varied natural environment." @default.
• W4382931034 created "2023-07-04" @default.
• W4382931034 creator A5040141007 @default.
• W4382931034 creator A5041312960 @default.
• W4382931034 creator A5047935898 @default.
• W4382931034 creator A5060731367 @default.
• W4382931034 creator A5066679306 @default.
• W4382931034 creator A5074461919 @default.
• W4382931034 date "2023-07-01" @default.
• W4382931034 modified "2023-10-14" @default.
• W4382931034 title "A C-type lectin in saliva of <i>Aedes albopictus</i> (Diptera: <i>Culicidae</i>) bind and agglutinate microorganisms with broad spectrum" @default.
• W4382931034 cites W1601252917 @default.
• W4382931034 cites W1976073075 @default.
• W4382931034 cites W1980071769 @default.
• W4382931034 cites W1984039687 @default.
• W4382931034 cites W1988940244 @default.
• W4382931034 cites W1998324728 @default.
• W4382931034 cites W2000589080 @default.
• W4382931034 cites W2002019043 @default.
• W4382931034 cites W2008716207 @default.
• W4382931034 cites W2010980655 @default.
• W4382931034 cites W2025098845 @default.
• W4382931034 cites W2026312907 @default.
• W4382931034 cites W2028071989 @default.
• W4382931034 cites W2035575648 @default.
• W4382931034 cites W2053470258 @default.
• W4382931034 cites W2055324984 @default.
• W4382931034 cites W2059257007 @default.
• W4382931034 cites W2060611796 @default.
• W4382931034 cites W2070993952 @default.
• W4382931034 cites W2074955153 @default.
• W4382931034 cites W2086391508 @default.
• W4382931034 cites W2098920876 @default.
• W4382931034 cites W2105613281 @default.
• W4382931034 cites W2125912444 @default.
• W4382931034 cites W2132901948 @default.
• W4382931034 cites W2142689912 @default.
• W4382931034 cites W2147257155 @default.
• W4382931034 cites W2176592904 @default.
• W4382931034 cites W2771087056 @default.
• W4382931034 cites W2789362784 @default.
• W4382931034 cites W2792332391 @default.
• W4382931034 cites W2793372731 @default.
• W4382931034 cites W2819565180 @default.
• W4382931034 cites W2920868010 @default.
• W4382931034 cites W3034086699 @default.
• W4382931034 cites W3037974412 @default.
• W4382931034 cites W3087977202 @default.
• W4382931034 cites W3126728396 @default.
• W4382931034 cites W3162924517 @default.
• W4382931034 cites W3176185445 @default.
• W4382931034 cites W4206353602 @default.
• W4382931034 doi "https://doi.org/10.1093/jisesa/iead043" @default.
• W4382931034 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37399114" @default.
• W4382931034 hasPublicationYear "2023" @default.
• W4382931034 type Work @default.
• W4382931034 citedByCount "0" @default.
• W4382931034 crossrefType "journal-article" @default.
• W4382931034 hasAuthorship W4382931034A5040141007 @default.
• W4382931034 hasAuthorship W4382931034A5041312960 @default.
• W4382931034 hasAuthorship W4382931034A5047935898 @default.
• W4382931034 hasAuthorship W4382931034A5060731367 @default.
• W4382931034 hasAuthorship W4382931034A5066679306 @default.
• W4382931034 hasAuthorship W4382931034A5074461919 @default.
• W4382931034 hasBestOaLocation W43829310341 @default.
• W4382931034 hasConcept C106257327 @default.
• W4382931034 hasConcept C136449434 @default.
• W4382931034 hasConcept C143508840 @default.
• W4382931034 hasConcept C153911025 @default.
• W4382931034 hasConcept C159047783 @default.
• W4382931034 hasConcept C159654299 @default.
• W4382931034 hasConcept C173758957 @default.
• W4382931034 hasConcept C203014093 @default.
• W4382931034 hasConcept C2776853612 @default.
• W4382931034 hasConcept C2777775583 @default.
• W4382931034 hasConcept C2779635636 @default.
• W4382931034 hasConcept C2780758401 @default.
• W4382931034 hasConcept C504460877 @default.
• W4382931034 hasConcept C533803919 @default.
• W4382931034 hasConcept C55493867 @default.
• W4382931034 hasConcept C59822182 @default.
• W4382931034 hasConcept C86803240 @default.
• W4382931034 hasConcept C8891405 @default.
• W4382931034 hasConcept C89423630 @default.
• W4382931034 hasConceptScore W4382931034C106257327 @default.
• W4382931034 hasConceptScore W4382931034C136449434 @default.
• W4382931034 hasConceptScore W4382931034C143508840 @default.
• W4382931034 hasConceptScore W4382931034C153911025 @default.
• W4382931034 hasConceptScore W4382931034C159047783 @default.
• W4382931034 hasConceptScore W4382931034C159654299 @default.
• W4382931034 hasConceptScore W4382931034C173758957 @default.
• W4382931034 hasConceptScore W4382931034C203014093 @default.
• W4382931034 hasConceptScore W4382931034C2776853612 @default.
• W4382931034 hasConceptScore W4382931034C2777775583 @default.
• W4382931034 hasConceptScore W4382931034C2779635636 @default.
• W4382931034 hasConceptScore W4382931034C2780758401 @default.
• W4382931034 hasConceptScore W4382931034C504460877 @default.
• W4382931034 hasConceptScore W4382931034C533803919 @default.
• W4382931034 hasConceptScore W4382931034C55493867 @default.
• W4382931034 hasConceptScore W4382931034C59822182 @default.

• next