FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4382931100> ?p ?o ?g. }

• W4382931100 abstract "Abstract Auditory sensation is based in nanoscale vibration of the sensory tissue of the cochlea, the organ of Corti complex (OCC). Motion within the OCC is now observable due to optical coherence tomography. In the cochlear base, in response to sound stimulation, the region that includes the electro-motile outer hair cells (OHC) was observed to move with larger amplitude than the basilar membrane (BM) and surrounding regions. The intense motion is based in active cell mechanics, and the region was termed the “hotspot” (Cooper et al., 2018, Nature comm). In addition to this quantitative distinction, the hotspot moved qualitatively differently than the BM, in that its motion scaled nonlinearly with stimulus level at all frequencies, evincing sub-BF activity. Sub-BF activity enhances non-BF motion; thus the frequency tuning of the hotspot was reduced relative to the BM. Regions that did not exhibit sub-BF activity are here defined as the OCC “frame”. By this definition the frame includes the BM, the medial and lateral OCC, and most significantly, the reticular lamina (RL). The frame concept groups the majority OCC as a structure that is largely shielded from sub-BF activity. This shielding, and how it is achieved, are key to the active frequency tuning of the cochlea. The observation that the RL does not move actively sub-BF indicates that hair cell stereocilia are not exposed to sub-BF activity. A complex difference analysis reveals the motion of the hotspot relative to the frame." @default.
• W4382931100 created "2023-07-04" @default.
• W4382931100 creator A5008060028 @default.
• W4382931100 creator A5037349567 @default.
• W4382931100 creator A5042595605 @default.
• W4382931100 creator A5054682248 @default.
• W4382931100 creator A5092383956 @default.
• W4382931100 date "2023-06-30" @default.
• W4382931100 modified "2023-10-18" @default.
• W4382931100 title "A frame and a hotspot in cochlear mechanics" @default.
• W4382931100 cites W1968720037 @default.
• W4382931100 cites W1969250228 @default.
• W4382931100 cites W1978648692 @default.
• W4382931100 cites W1981134683 @default.
• W4382931100 cites W2005100218 @default.
• W4382931100 cites W2018729336 @default.
• W4382931100 cites W2030882845 @default.
• W4382931100 cites W2036788442 @default.
• W4382931100 cites W2046921710 @default.
• W4382931100 cites W2046942711 @default.
• W4382931100 cites W2058790681 @default.
• W4382931100 cites W2075437668 @default.
• W4382931100 cites W2079165672 @default.
• W4382931100 cites W2091326036 @default.
• W4382931100 cites W2091367757 @default.
• W4382931100 cites W2095165307 @default.
• W4382931100 cites W2161820166 @default.
• W4382931100 cites W2218301003 @default.
• W4382931100 cites W2411321577 @default.
• W4382931100 cites W2413868262 @default.
• W4382931100 cites W2476266271 @default.
• W4382931100 cites W2536199397 @default.
• W4382931100 cites W2572441277 @default.
• W4382931100 cites W2773892299 @default.
• W4382931100 cites W2805826176 @default.
• W4382931100 cites W2891813614 @default.
• W4382931100 cites W2909193466 @default.
• W4382931100 cites W2940080851 @default.
• W4382931100 cites W3030219885 @default.
• W4382931100 cites W3092825949 @default.
• W4382931100 cites W3153827029 @default.
• W4382931100 cites W3210184154 @default.
• W4382931100 cites W4200599578 @default.
• W4382931100 cites W4213057620 @default.
• W4382931100 cites W4281636701 @default.
• W4382931100 cites W4296448329 @default.
• W4382931100 cites W4306407142 @default.
• W4382931100 cites W4307045972 @default.
• W4382931100 cites W4308296611 @default.
• W4382931100 cites W4309507254 @default.
• W4382931100 cites W4309756930 @default.
• W4382931100 cites W4321615139 @default.
• W4382931100 cites W4367601123 @default.
• W4382931100 doi "https://doi.org/10.1101/2023.06.29.547111" @default.
• W4382931100 hasPublicationYear "2023" @default.
• W4382931100 type Work @default.
• W4382931100 citedByCount "0" @default.
• W4382931100 crossrefType "posted-content" @default.
• W4382931100 hasAuthorship W4382931100A5008060028 @default.
• W4382931100 hasAuthorship W4382931100A5037349567 @default.
• W4382931100 hasAuthorship W4382931100A5042595605 @default.
• W4382931100 hasAuthorship W4382931100A5054682248 @default.
• W4382931100 hasAuthorship W4382931100A5092383956 @default.
• W4382931100 hasBestOaLocation W43829311001 @default.
• W4382931100 hasConcept C105702510 @default.
• W4382931100 hasConcept C121332964 @default.
• W4382931100 hasConcept C146481406 @default.
• W4382931100 hasConcept C15744967 @default.
• W4382931100 hasConcept C2778585322 @default.
• W4382931100 hasConcept C2779918689 @default.
• W4382931100 hasConcept C2780130748 @default.
• W4382931100 hasConcept C2780659331 @default.
• W4382931100 hasConcept C2780807236 @default.
• W4382931100 hasConcept C542102704 @default.
• W4382931100 hasConcept C8058405 @default.
• W4382931100 hasConcept C86803240 @default.
• W4382931100 hasConceptScore W4382931100C105702510 @default.
• W4382931100 hasConceptScore W4382931100C121332964 @default.
• W4382931100 hasConceptScore W4382931100C146481406 @default.
• W4382931100 hasConceptScore W4382931100C15744967 @default.
• W4382931100 hasConceptScore W4382931100C2778585322 @default.
• W4382931100 hasConceptScore W4382931100C2779918689 @default.
• W4382931100 hasConceptScore W4382931100C2780130748 @default.
• W4382931100 hasConceptScore W4382931100C2780659331 @default.
• W4382931100 hasConceptScore W4382931100C2780807236 @default.
• W4382931100 hasConceptScore W4382931100C542102704 @default.
• W4382931100 hasConceptScore W4382931100C8058405 @default.
• W4382931100 hasConceptScore W4382931100C86803240 @default.
• W4382931100 hasLocation W43829311001 @default.
• W4382931100 hasOpenAccess W4382931100 @default.
• W4382931100 hasPrimaryLocation W43829311001 @default.
• W4382931100 hasRelatedWork W1975610963 @default.
• W4382931100 hasRelatedWork W2024249585 @default.
• W4382931100 hasRelatedWork W2025447940 @default.
• W4382931100 hasRelatedWork W2036288638 @default.
• W4382931100 hasRelatedWork W2050575927 @default.
• W4382931100 hasRelatedWork W2091099858 @default.
• W4382931100 hasRelatedWork W2142535900 @default.
• W4382931100 hasRelatedWork W2220106465 @default.
• W4382931100 hasRelatedWork W2322456067 @default.

• next